| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.178258 |
| MTSS1 | metastasis suppressor 1 | 0.0645708 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0588648 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0501922 |
| PODXL | podocalyxin-like | 0.0469535 |
| TGM2 | transglutaminase 2 | 0.0457626 |
| RAI14 | retinoic acid induced 14 | 0.0430469 |
| LAMC2 | laminin, gamma 2 | 0.0418978 |
| HLA-E | major histocompatibility complex, class I, E | 0.0407853 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0382112 |
| B2M | beta-2-microglobulin | 0.0371222 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0363005 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0348739 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0344225 |
| IGF2 | insulin-like growth factor 2 | 0.0343548 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.032973 |
| INTS6 | integrator complex subunit 6 | 0.0327244 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0313367 |
| NCOR2 | nuclear receptor corepressor 2 | 0.030445 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0302193 |
| MT1E | metallothionein 1E | 0.0302019 |
| LAMB3 | laminin, beta 3 | 0.0300732 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0299624 |
| EGFR | epidermal growth factor receptor | 0.0297475 |
| DOK5 | docking protein 5 | 0.0291577 |
| MSN | moesin | 0.0288843 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0278617 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0278112 |
| RPS8 | ribosomal protein S8 | 0.0277503 |
| SLC35F3 | solute carrier family 35, member F3 | 0.027628 |
| PLEC | plectin | 0.027492 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0271885 |
| HMGA2 | high mobility group AT-hook 2 | 0.0269315 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0264365 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0258551 |
| FTL | ferritin, light polypeptide | 0.0256709 |
| CD9 | CD9 molecule | 0.0254712 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0254285 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0253929 |
| PCDH1 | protocadherin 1 | 0.025208 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0241628 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0239628 |
| IFI44L | interferon-induced protein 44-like | 0.0234948 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0231604 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0229188 |
| RPL37A | ribosomal protein L37a | 0.0224886 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0224759 |
| SQSTM1 | sequestosome 1 | 0.022354 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0222142 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0219715 |
| TRIM56 | tripartite motif containing 56 | 0.02169 |
| ITGB8 | integrin, beta 8 | 0.0216171 |
| NAV2 | neuron navigator 2 | 0.0215899 |
| PRSS23 | protease, serine, 23 | 0.0212851 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.021263 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0212589 |
| VEGFA | vascular endothelial growth factor A | 0.0209363 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0208367 |
| CORO2A | coronin, actin binding protein, 2A | 0.0206679 |
| RPS27 | ribosomal protein S27 | 0.0206294 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0202133 |
| SULF2 | sulfatase 2 | 0.0201332 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0200852 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0200707 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0200551 |
| RNF213 | ring finger protein 213 | 0.019916 |
| EFHD2 | EF-hand domain family, member D2 | 0.019667 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0195805 |
| ECE1 | endothelin converting enzyme 1 | 0.0191906 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0189746 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0188828 |
| TPM4 | tropomyosin 4 | 0.0187388 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0186589 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0185159 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0183141 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | 0.0182088 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.0178924 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0176868 |
| ABHD17C | abhydrolase domain containing 17C | 0.0175986 |
| CEP250 | centrosomal protein 250kDa | 0.0172784 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0172558 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0172148 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.017205 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0171588 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.0170735 |
| ATP9A | ATPase, class II, type 9A | 0.0167936 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0167571 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0164739 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0164449 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.016359 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0163111 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0162689 |
| KIAA1671 | KIAA1671 | 0.0161957 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0161609 |
| RPL37 | ribosomal protein L37 | 0.016092 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0160871 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.0160495 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.015974 |
| TBC1D22A | TBC1 domain family, member 22A | 0.015926 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.015828 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MYOF | myoferlin | -0.098891 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.097501 |
| FLNB | filamin B, beta | -0.0961842 |
| FOXO1 | forkhead box O1 | -0.0957546 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0934035 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0881861 |
| PRELID2 | PRELI domain containing 2 | -0.0753563 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0731621 |
| RBM39 | RNA binding motif protein 39 | -0.0710705 |
| RPS21 | ribosomal protein S21 | -0.0703598 |
| SULF1 | sulfatase 1 | -0.0688964 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0687486 |
| CD44 | CD44 molecule (Indian blood group) | -0.0675578 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0668075 |
| TMSB10 | thymosin beta 10 | -0.0651773 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0631934 |
| ITGA6 | integrin, alpha 6 | -0.062979 |
| ANKRD33B | ankyrin repeat domain 33B | -0.061488 |
| ASPH | aspartate beta-hydroxylase | -0.0614836 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.059083 |
| ENO1 | enolase 1, (alpha) | -0.0572236 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0534474 |
| NRG1 | neuregulin 1 | -0.0530289 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0513842 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0505481 |
| LMO7 | LIM domain 7 | -0.050534 |
| VCL | vinculin | -0.0505236 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0497721 |
| EMP1 | epithelial membrane protein 1 | -0.0487704 |
| NEK7 | NIMA-related kinase 7 | -0.0485867 |
| SMAD3 | SMAD family member 3 | -0.0469292 |
| KRT17 | keratin 17, type I | -0.045844 |
| GNAS | GNAS complex locus | -0.0457194 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0451737 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0435732 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0434157 |
| FOXP1 | forkhead box P1 | -0.0429257 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0425494 |
| AHNAK | AHNAK nucleoprotein | -0.0413377 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0408611 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0408427 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.040765 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0395563 |
| CANX | calnexin | -0.0394189 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0391191 |
| TMSB4X | thymosin beta 4, X-linked | -0.0382258 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0381991 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0379126 |
| AOPEP | aminopeptidase O (putative) | -0.0371675 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0369203 |
| ANLN | anillin, actin binding protein | -0.0361932 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0361917 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0361905 |
| EZR | ezrin | -0.0361131 |
| ANXA1 | annexin A1 | -0.0358317 |
| PGK1 | phosphoglycerate kinase 1 | -0.0356555 |
| OGA | O-GlcNAcase | -0.0355506 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0355218 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0353774 |
| H1-0 | H1.0 linker histone | -0.03533 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0353012 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0348997 |
| LDHA | lactate dehydrogenase A | -0.0345884 |
| ANXA2 | annexin A2 | -0.0343181 |
| LMNA | lamin A/C | -0.0342027 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0341845 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0341459 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0341281 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0337876 |
| DOCK5 | dedicator of cytokinesis 5 | -0.033787 |
| RIN2 | Ras and Rab interactor 2 | -0.0337697 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0334638 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0332387 |
| CUL4B | cullin 4B | -0.0331623 |
| FLNA | filamin A, alpha | -0.0331223 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0329748 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0329718 |
| TXNRD1 | thioredoxin reductase 1 | -0.0329098 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0326771 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0325322 |
| YBX3 | Y box binding protein 3 | -0.0323282 |
| MYO10 | myosin X | -0.0322979 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0319444 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0315442 |
| PLAT | plasminogen activator, tissue | -0.0315164 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.031054 |
| OSMR | oncostatin M receptor | -0.0303118 |
| ACTN4 | actinin, alpha 4 | -0.0302205 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0301245 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0298873 |
| DIAPH3 | diaphanous-related formin 3 | -0.0297488 |
| CENPF | centromere protein F, 350/400kDa | -0.0296007 |
| FNIP1 | folliculin interacting protein 1 | -0.0295611 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0295047 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0294226 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.028997 |
| EHF | ets homologous factor | -0.0286809 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0276451 |
| QKI | QKI, KH domain containing, RNA binding | -0.0275997 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0273574 |
