| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-C | major histocompatibility complex, class I, C | 0.0568442 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0443005 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0280607 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0266946 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.026109 |
| MT2A | metallothionein 2A | 0.024621 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0242459 |
| NDRG1 | N-myc downstream regulated 1 | 0.0234757 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0186314 |
| EGFR | epidermal growth factor receptor | 0.0160188 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0149211 |
| MSN | moesin | 0.0131131 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0130712 |
| LUZP1 | leucine zipper protein 1 | 0.0129082 |
| RBM26 | RNA binding motif protein 26 | 0.0127154 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0121332 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0120598 |
| TPM3 | tropomyosin 3 | 0.0119435 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0118128 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0108384 |
| EEFSEC | eukaryotic elongation factor, selenocysteine-tRNA-specific | 0.0108301 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.010786 |
| CMIP | c-Maf inducing protein | 0.0103748 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0103659 |
| ERBIN | erbb2 interacting protein | 0.0102039 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.010121 |
| FLNA | filamin A, alpha | 0.0100428 |
| ANGPTL4 | angiopoietin-like 4 | 0.00982702 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.00973189 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00969671 |
| BCL2L1 | BCL2-like 1 | 0.00963851 |
| PODXL | podocalyxin-like | 0.00957557 |
| MGLL | monoglyceride lipase | 0.00957038 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.00952821 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0094945 |
| RASA3 | RAS p21 protein activator 3 | 0.00946905 |
| FLOT1 | flotillin 1 | 0.00923149 |
| MCL1 | myeloid cell leukemia 1 | 0.00918446 |
| DOCK5 | dedicator of cytokinesis 5 | 0.00908731 |
| ANKRD36 | ankyrin repeat domain 36 | 0.00899393 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.00898578 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00880507 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.00878868 |
| AXL | AXL receptor tyrosine kinase | 0.00877471 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.00863719 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.00850315 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.00835226 |
| RASA2 | RAS p21 protein activator 2 | 0.00834145 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.00818289 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0081523 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.00799925 |
| VEGFA | vascular endothelial growth factor A | 0.00798711 |
| CEP250 | centrosomal protein 250kDa | 0.00798458 |
| PLCG1 | phospholipase C, gamma 1 | 0.00788659 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.00775455 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.00771739 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.00768286 |
| PLXNA1 | plexin A1 | 0.00764079 |
| SYNJ2 | synaptojanin 2 | 0.00761109 |
| SATB2 | SATB homeobox 2 | 0.00758149 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.00751193 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00741828 |
| RAD51B | RAD51 paralog B | 0.00739093 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.00737807 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.00732428 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.00731798 |
| MLPH | melanophilin | 0.00728208 |
| ZNF652 | zinc finger protein 652 | 0.00723171 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.00720879 |
| TNIK | TRAF2 and NCK interacting kinase | 0.00715944 |
| CUL4A | cullin 4A | 0.00712392 |
| RELL1 | RELT-like 1 | 0.00706777 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.00703102 |
| BLCAP | bladder cancer associated protein | 0.00700985 |
| ATG10 | autophagy related 10 | 0.00696932 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.00691723 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00679298 |
| RTN4 | reticulon 4 | 0.00678175 |
| SZT2 | seizure threshold 2 homolog (mouse) | 0.0067747 |
| RIPOR1 | RHO family interacting cell polarization regulator 1 | 0.00673399 |
| FOXP1 | forkhead box P1 | 0.00669715 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0066915 |
| TSPAN14 | tetraspanin 14 | 0.00668379 |
| KRIT1 | KRIT1, ankyrin repeat containing | 0.00667944 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.00667052 |
| PVR | poliovirus receptor | 0.00663688 |
| MEAK7 | MTOR associated protein, eak-7 homolog | 0.00662806 |
| PROS1 | protein S (alpha) | 0.00661722 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00659307 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.00653329 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.00650965 |
| SP3 | Sp3 transcription factor | 0.00643945 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.00643651 |
| EFNA5 | ephrin-A5 | 0.00643067 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0064279 |
| TMEM14C | transmembrane protein 14C | 0.00638609 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.00632102 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 | 0.00629377 |
| TARDBP | TAR DNA binding protein | 0.00628358 |
| CAPRIN2 | caprin family member 2 | 0.00627493 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.257285 |
| HLA-B | major histocompatibility complex, class I, B | -0.161321 |
| FTL | ferritin, light polypeptide | -0.158624 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.135727 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.107758 |
| EXT1 | exostosin glycosyltransferase 1 | -0.101259 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0999512 |
| PTMA | prothymosin, alpha | -0.0671146 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0670186 |
| TMSB10 | thymosin beta 10 | -0.0648865 |
| AHNAK | AHNAK nucleoprotein | -0.0635236 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.059473 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0575269 |
| B2M | beta-2-microglobulin | -0.0496276 |
| PGK1 | phosphoglycerate kinase 1 | -0.0458574 |
| TXNRD1 | thioredoxin reductase 1 | -0.0447701 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0431634 |
| LDHA | lactate dehydrogenase A | -0.042748 |
| PKM | pyruvate kinase, muscle | -0.0419867 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0413697 |
| S100A10 | S100 calcium binding protein A10 | -0.0411176 |
| RPS6 | ribosomal protein S6 | -0.0403537 |
| RBM39 | RNA binding motif protein 39 | -0.0403302 |
| CANX | calnexin | -0.0401576 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0394133 |
| GNAS | GNAS complex locus | -0.0391568 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0380197 |
| RPLP2 | ribosomal protein, large, P2 | -0.0369462 |
| DEK | DEK proto-oncogene | -0.0367387 |
| GOLGA4 | golgin A4 | -0.0365747 |
| JUN | jun proto-oncogene | -0.0360852 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0355386 |
| RAD21 | RAD21 homolog (S. pombe) | -0.034181 |
| CALR | calreticulin | -0.0337714 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0329278 |
| UBC | ubiquitin C | -0.0328525 |
| FUS | FUS RNA binding protein | -0.0328041 |
| MT1X | metallothionein 1X | -0.0327024 |
| RND3 | Rho family GTPase 3 | -0.0323952 |
| TMSB4X | thymosin beta 4, X-linked | -0.0318663 |
| PLCB4 | phospholipase C, beta 4 | -0.031749 |
| ENO1 | enolase 1, (alpha) | -0.03174 |
| MAP4 | microtubule-associated protein 4 | -0.0312142 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0309551 |
| HLA-A | major histocompatibility complex, class I, A | -0.030853 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.030418 |
| ADM | adrenomedullin | -0.0302668 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0301377 |
| KRT7 | keratin 7, type II | -0.0299824 |
| SQSTM1 | sequestosome 1 | -0.0290739 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0287123 |
| RPL23 | ribosomal protein L23 | -0.0280506 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0279843 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0279535 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0278998 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0275193 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0274236 |
| HMGB1 | high mobility group box 1 | -0.0273853 |
| QKI | QKI, KH domain containing, RNA binding | -0.0273003 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0272871 |
| ANXA1 | annexin A1 | -0.0272536 |
| KRT8 | keratin 8, type II | -0.0270976 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0265934 |
| RLF | rearranged L-myc fusion | -0.0264155 |
| HMGB2 | high mobility group box 2 | -0.026175 |
| RPL12 | ribosomal protein L12 | -0.0261658 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0261486 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0261405 |
| RPLP1 | ribosomal protein, large, P1 | -0.0260995 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0251505 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.024816 |
| PTK2 | protein tyrosine kinase 2 | -0.0246981 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0245393 |
| TPD52 | tumor protein D52 | -0.0242936 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0238589 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0237843 |
| LMNA | lamin A/C | -0.0237287 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0237243 |
| RYBP | RING1 and YY1 binding protein | -0.0237151 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0236036 |
| VIM | vimentin | -0.0234566 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0234408 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0232331 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0232063 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0231012 |
| CTSD | cathepsin D | -0.0230634 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0229126 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0228461 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0227378 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.022684 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0226753 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0226376 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0224685 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0224153 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.022379 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0222698 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0222473 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0220836 |
| MAP1B | microtubule-associated protein 1B | -0.0219923 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0214385 |
