| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0726096 |
| ACTG1 | actin gamma 1 | 0.0602074 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0585308 |
| EGR1 | early growth response 1 | 0.0434021 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0419309 |
| FLNA | filamin A, alpha | 0.0415012 |
| LDHA | lactate dehydrogenase A | 0.0413674 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0409366 |
| POTEF | POTE ankyrin domain family, member F | 0.0384204 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0369997 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0368104 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0341647 |
| SET | SET nuclear proto-oncogene | 0.0331997 |
| MSN | moesin | 0.0325761 |
| SMAD3 | SMAD family member 3 | 0.0323087 |
| MCL1 | myeloid cell leukemia 1 | 0.0314096 |
| INTS6 | integrator complex subunit 6 | 0.0303658 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0299918 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0290067 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0288825 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0285372 |
| STC1 | stanniocalcin 1 | 0.028145 |
| HMGA1 | high mobility group AT-hook 1 | 0.0279266 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0268767 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0262038 |
| RNF213 | ring finger protein 213 | 0.0259431 |
| NAV1 | neuron navigator 1 | 0.0258961 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0258193 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0253969 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0249216 |
| ENO1 | enolase 1, (alpha) | 0.024291 |
| RPS4X | ribosomal protein S4, X-linked | 0.0231449 |
| NDRG1 | N-myc downstream regulated 1 | 0.0228352 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0228152 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0218951 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0215189 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0209114 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0205951 |
| ITGA6 | integrin, alpha 6 | 0.0201631 |
| PFN1 | profilin 1 | 0.0200082 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0199893 |
| RPL9 | ribosomal protein L9 | 0.0198121 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0197996 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0197605 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.019357 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0192733 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0187935 |
| TLN1 | talin 1 | 0.0185081 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0179945 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0177035 |
| UTRN | utrophin | 0.0175929 |
| RPL21 | ribosomal protein L21 | 0.0174523 |
| RAD51B | RAD51 paralog B | 0.0172264 |
| SORCS2 | sortilin-related VPS10 domain containing receptor 2 | 0.0170854 |
| GOLGB1 | golgin B1 | 0.0168095 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0164984 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0164158 |
| ASPH | aspartate beta-hydroxylase | 0.0163859 |
| CENPF | centromere protein F, 350/400kDa | 0.0163679 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0161057 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0159584 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | 0.0159218 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0158428 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0157636 |
| SAMD3 | sterile alpha motif domain containing 3 | 0.0157305 |
| GLIS3 | GLIS family zinc finger 3 | 0.0157135 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.015664 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0151867 |
| SQSTM1 | sequestosome 1 | 0.0150837 |
| FLNB | filamin B, beta | 0.014995 |
| WWOX | WW domain containing oxidoreductase | 0.0149687 |
| CEP112 | centrosomal protein 112kDa | 0.0149164 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0148992 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0148889 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0148329 |
| KLF12 | Kruppel-like factor 12 | 0.014751 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0147262 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0146954 |
| PCBP2 | poly(rC) binding protein 2 | 0.0146317 |
| TAPBP | TAP binding protein (tapasin) | 0.0146264 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0143886 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0143372 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0142952 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0142474 |
| CD44 | CD44 molecule (Indian blood group) | 0.0142425 |
| ATXN1 | ataxin 1 | 0.0140088 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0139997 |
| MKI67 | marker of proliferation Ki-67 | 0.013826 |
| KIAA1328 | KIAA1328 | 0.0136236 |
| PRELID2 | PRELI domain containing 2 | 0.0135387 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0134763 |
| LOXL2 | lysyl oxidase-like 2 | 0.0134587 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.0134293 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0133748 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.013308 |
| RASAL2 | RAS protein activator like 2 | 0.0132383 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0131292 |
| FN1 | fibronectin 1 | 0.0130757 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0129606 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0128819 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.282548 |
| DTNA | dystrobrevin, alpha | -0.23966 |
| EXT1 | exostosin glycosyltransferase 1 | -0.148343 |
| LSAMP | limbic system-associated membrane protein | -0.138418 |
| RUNX1 | runt-related transcription factor 1 | -0.0960017 |
| MYO10 | myosin X | -0.0950964 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0909243 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0909176 |
| MMP12 | matrix metallopeptidase 12 | -0.0861395 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0852201 |
| RPS6 | ribosomal protein S6 | -0.0807659 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0767299 |
| EFNA5 | ephrin-A5 | -0.0745389 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0735154 |
| PTK2 | protein tyrosine kinase 2 | -0.0653666 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0640203 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0625851 |
| SPAG9 | sperm associated antigen 9 | -0.0598204 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0581432 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.051695 |
| GPC6 | glypican 6 | -0.0514975 |
| CDK17 | cyclin-dependent kinase 17 | -0.0514449 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0509274 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0498301 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0477293 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0475425 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0473394 |
| NTM | neurotrimin | -0.0469233 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0468653 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0455431 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0448464 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0446384 |
| ATP13A3 | ATPase type 13A3 | -0.044111 |
| HAS2 | hyaluronan synthase 2 | -0.0434827 |
| ANXA2 | annexin A2 | -0.0427827 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0426768 |
| WDR45B | WD repeat domain 45B | -0.0414752 |
| RPL23 | ribosomal protein L23 | -0.0414072 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.041147 |
| RPLP1 | ribosomal protein, large, P1 | -0.0409297 |
| SBF2 | SET binding factor 2 | -0.0399779 |
| YBX3 | Y box binding protein 3 | -0.0395145 |
| RBM39 | RNA binding motif protein 39 | -0.0393516 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0391201 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0388417 |
| GOLGA4 | golgin A4 | -0.0387993 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0377485 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0374035 |
| MAP4 | microtubule-associated protein 4 | -0.0373036 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0368356 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0362335 |
| WDR43 | WD repeat domain 43 | -0.0361347 |
| APP | amyloid beta (A4) precursor protein | -0.0360905 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0358478 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0355394 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0353297 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0351827 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.035091 |
| PGK1 | phosphoglycerate kinase 1 | -0.0349208 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0348281 |
| RLF | rearranged L-myc fusion | -0.0347747 |
| NUP58 | nucleoporin 58 | -0.0345473 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0344866 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0344154 |
| FTL | ferritin, light polypeptide | -0.0341952 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0340107 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0336228 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0334576 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0333729 |
| VCL | vinculin | -0.0332795 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0332198 |
| JMJD1C | jumonji domain containing 1C | -0.0330738 |
| MSR1 | macrophage scavenger receptor 1 | -0.0329606 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0327877 |
| CDH13 | cadherin 13 | -0.0322528 |
| RASA2 | RAS p21 protein activator 2 | -0.0321896 |
| PARD3 | par-3 family cell polarity regulator | -0.0321598 |
| RPS27A | ribosomal protein S27a | -0.0320822 |
| PTMA | prothymosin, alpha | -0.031996 |
| CFAP251 | cilia and flagella associated protein 251 | -0.031975 |
| MALT1 | MALT1 paracaspase | -0.031942 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0315361 |
| TMSB10 | thymosin beta 10 | -0.0314963 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0314022 |
| RPLP2 | ribosomal protein, large, P2 | -0.0313989 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0313966 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0303912 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0302809 |
| RAB6A | RAB6A, member RAS oncogene family | -0.029991 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0296546 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0294454 |
| NF1 | neurofibromin 1 | -0.0294143 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0292525 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0292409 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0288227 |
| RPS24 | ribosomal protein S24 | -0.0287612 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0287388 |
| RPS13 | ribosomal protein S13 | -0.0286114 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0285186 |
| RND3 | Rho family GTPase 3 | -0.0283529 |
