| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0605079 |
| ACTG1 | actin gamma 1 | 0.0601638 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0480216 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0286236 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0259887 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0256047 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0250597 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0250336 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.023371 |
| GOLGA4 | golgin A4 | 0.02155 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0206738 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0205396 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0201531 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0189856 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0185982 |
| RACK1 | receptor for activated C kinase 1 | 0.0181539 |
| HLA-C | major histocompatibility complex, class I, C | 0.0176487 |
| TXNRD1 | thioredoxin reductase 1 | 0.0173142 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0168495 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0164931 |
| GDF15 | growth differentiation factor 15 | 0.0161187 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0161184 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.016063 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0155245 |
| CYP2S1 | cytochrome P450, family 2, subfamily S, polypeptide 1 | 0.0154615 |
| CLINT1 | clathrin interactor 1 | 0.0152473 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0152185 |
| TRIM31 | tripartite motif containing 31 | 0.015007 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0147585 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0147054 |
| ARRDC3 | arrestin domain containing 3 | 0.0146558 |
| ABHD2 | abhydrolase domain containing 2 | 0.0143148 |
| BRD2 | bromodomain containing 2 | 0.0140779 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0135947 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0133747 |
| RNF145 | ring finger protein 145 | 0.0133227 |
| POTEF | POTE ankyrin domain family, member F | 0.0131683 |
| NDRG1 | N-myc downstream regulated 1 | 0.0130798 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0130681 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0130598 |
| LRRC1 | leucine rich repeat containing 1 | 0.0130302 |
| TMEM165 | transmembrane protein 165 | 0.0129318 |
| FOXO1 | forkhead box O1 | 0.0129256 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.0129242 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0128662 |
| TMF1 | TATA element modulatory factor 1 | 0.0127873 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0127735 |
| FERMT1 | fermitin family member 1 | 0.0126814 |
| RPS3 | ribosomal protein S3 | 0.0126424 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0125848 |
| MLEC | malectin | 0.0124747 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.0124422 |
| PTEN | phosphatase and tensin homolog | 0.0122725 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0122262 |
| PCM1 | pericentriolar material 1 | 0.0120372 |
| CXADR | coxsackie virus and adenovirus receptor | 0.01179 |
| CSNK1G3 | casein kinase 1, gamma 3 | 0.0116748 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0116286 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0115434 |
| CBX3 | chromobox homolog 3 | 0.0114015 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0113651 |
| RBM26 | RNA binding motif protein 26 | 0.0112647 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0112442 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0112345 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0109413 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0109393 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0109389 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0108648 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.010862 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0107988 |
| PCBP2 | poly(rC) binding protein 2 | 0.0107641 |
| CLTC | clathrin, heavy chain (Hc) | 0.0106533 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.0106458 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0106285 |
| PDZD8 | PDZ domain containing 8 | 0.0104056 |
| UBE3A | ubiquitin protein ligase E3A | 0.0103801 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0103199 |
| ITGB4 | integrin, beta 4 | 0.0102531 |
| XPO1 | exportin 1 | 0.0102511 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0102361 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0101859 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0100652 |
| SLK | STE20-like kinase | 0.0100591 |
| CENPF | centromere protein F, 350/400kDa | 0.0100556 |
| MKI67 | marker of proliferation Ki-67 | 0.0100262 |
| CCNC | cyclin C | 0.00999457 |
| EEA1 | early endosome antigen 1 | 0.00996167 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.00993426 |
| TNS4 | tensin 4 | 0.00991809 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.00989532 |
| RTN4 | reticulon 4 | 0.00989367 |
| MINK1 | misshapen-like kinase 1 | 0.00976369 |
| FAT1 | FAT atypical cadherin 1 | 0.00974095 |
| ERBIN | erbb2 interacting protein | 0.00957073 |
| NKTR | natural killer cell triggering receptor | 0.00949891 |
| RFX7 | regulatory factor X, 7 | 0.0094657 |
| DSCAM | Down syndrome cell adhesion molecule | 0.00945543 |
| DEK | DEK proto-oncogene | 0.00941346 |
| CD47 | CD47 molecule | 0.00939103 |
| TMEM87A | transmembrane protein 87A | 0.00935728 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.112329 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.101052 |
| MYO1E | myosin IE | -0.093957 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0918359 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0916444 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0868813 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0771016 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0676725 |
| INTS6 | integrator complex subunit 6 | -0.0671263 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0652515 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0636224 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0609138 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0603325 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0587992 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0548799 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0506303 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0503404 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0497441 |
| KRT8 | keratin 8, type II | -0.04974 |
| FRMD5 | FERM domain containing 5 | -0.0495226 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0492719 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.049207 |
| VCL | vinculin | -0.0481769 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0477166 |
| CUX1 | cut-like homeobox 1 | -0.0475992 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0467635 |
| ANXA2 | annexin A2 | -0.0461862 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0445065 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0441095 |
| SP100 | SP100 nuclear antigen | -0.0429368 |
| MSI2 | musashi RNA-binding protein 2 | -0.0419095 |
| SPINK13 | serine peptidase inhibitor, Kazal type 13 (putative) | -0.0409925 |
| SERINC5 | serine incorporator 5 | -0.0402354 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0401138 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0400395 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0395902 |
| RPS24 | ribosomal protein S24 | -0.0391492 |
| RPS12 | ribosomal protein S12 | -0.0384675 |
| TMSB10 | thymosin beta 10 | -0.0382488 |
| ACTN4 | actinin, alpha 4 | -0.0378159 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0371422 |
| FBXO11 | F-box protein 11 | -0.0370787 |
| PTMA | prothymosin, alpha | -0.0362842 |
| RPL4 | ribosomal protein L4 | -0.0362556 |
| MYO5B | myosin VB | -0.0361344 |
| CTBP2 | C-terminal binding protein 2 | -0.036052 |
| PDLIM5 | PDZ and LIM domain 5 | -0.035857 |
| RPL34 | ribosomal protein L34 | -0.035399 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0340931 |
| IFRD1 | interferon-related developmental regulator 1 | -0.033869 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0337796 |
| RPS6 | ribosomal protein S6 | -0.0336115 |
| DENND1A | DENN/MADD domain containing 1A | -0.0335904 |
| PKM | pyruvate kinase, muscle | -0.0332491 |
| FUS | FUS RNA binding protein | -0.0332491 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0332303 |
| LRRC23 | leucine rich repeat containing 23 | -0.0331533 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0322831 |
| MCU | mitochondrial calcium uniporter | -0.0315957 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.031268 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0304917 |
| RAD51B | RAD51 paralog B | -0.0303615 |
| RIMKLB | ribosomal modification protein rimK-like family member B | -0.030116 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0298567 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0294362 |
| EXOC4 | exocyst complex component 4 | -0.0294025 |
| OXSR1 | oxidative stress responsive 1 | -0.0294023 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.0282722 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0282689 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.028161 |
| AOPEP | aminopeptidase O (putative) | -0.0280432 |
| UBAP2 | ubiquitin associated protein 2 | -0.0279257 |
| RPS23 | ribosomal protein S23 | -0.0278574 |
| PALLD | palladin, cytoskeletal associated protein | -0.0275679 |
| CANX | calnexin | -0.0275449 |
| NABP1 | nucleic acid binding protein 1 | -0.0274564 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0274521 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0274442 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0273709 |
| FHIT | fragile histidine triad | -0.0270767 |
| RPL26 | ribosomal protein L26 | -0.0269462 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.026854 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.026838 |
| RPS25 | ribosomal protein S25 | -0.0268283 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0266661 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0265821 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0265229 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0264742 |
| RPLP2 | ribosomal protein, large, P2 | -0.0263362 |
| RPS17 | ribosomal protein S17 | -0.0263039 |
| AHNAK | AHNAK nucleoprotein | -0.0261811 |
| RPL23 | ribosomal protein L23 | -0.0259473 |
| CLIC5 | chloride intracellular channel 5 | -0.0259134 |
| PATJ | PATJ crumbs cell polarity complex component | -0.025433 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0249328 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0248824 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0245876 |
| RPLP1 | ribosomal protein, large, P1 | -0.0243222 |
| SPON1 | spondin 1, extracellular matrix protein | -0.0241715 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0240874 |
