| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Elagolix sodium_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TP63 | tumor protein p63 | 0.0502301 |
| CAPRIN2 | caprin family member 2 | 0.0426024 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0394267 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0370625 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0354024 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0342883 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0336295 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0315826 |
| HLA-B | major histocompatibility complex, class I, B | 0.0311724 |
| CADM2 | cell adhesion molecule 2 | 0.0298891 |
| ANGPTL4 | angiopoietin-like 4 | 0.0296128 |
| RPS12 | ribosomal protein S12 | 0.0284538 |
| PLSCR1 | phospholipid scramblase 1 | 0.0267949 |
| PRELID2 | PRELI domain containing 2 | 0.0264045 |
| MT1E | metallothionein 1E | 0.0259095 |
| RPS3 | ribosomal protein S3 | 0.0247845 |
| HLA-C | major histocompatibility complex, class I, C | 0.0232254 |
| RACK1 | receptor for activated C kinase 1 | 0.0215904 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0214696 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.02102 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0208206 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0199108 |
| RPS8 | ribosomal protein S8 | 0.0194725 |
| RIGI | RNA sensor RIG-I | 0.0185992 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0183839 |
| TRIM56 | tripartite motif containing 56 | 0.0183545 |
| PDE10A | phosphodiesterase 10A | 0.0181027 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0175628 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0172737 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0170954 |
| RPL37A | ribosomal protein L37a | 0.0164549 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0164311 |
| B2M | beta-2-microglobulin | 0.0162856 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0162325 |
| FERMT1 | fermitin family member 1 | 0.0160587 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | 0.0158154 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0152765 |
| DNER | delta/notch-like EGF repeat containing | 0.0150209 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0147211 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0145571 |
| DST | dystonin | 0.0144372 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0143031 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0142141 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0142116 |
| SLK | STE20-like kinase | 0.0140312 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0137883 |
| RPS17 | ribosomal protein S17 | 0.0132985 |
| BARX2 | BARX homeobox 2 | 0.0129876 |
| RPS27 | ribosomal protein S27 | 0.012982 |
| SP100 | SP100 nuclear antigen | 0.0129694 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0127246 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0126087 |
| MEF2A | myocyte enhancer factor 2A | 0.0125784 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0125678 |
| PYGL | phosphorylase, glycogen, liver | 0.0123234 |
| RPL36 | ribosomal protein L36 | 0.0122898 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0122041 |
| OSMR | oncostatin M receptor | 0.0120037 |
| TGM2 | transglutaminase 2 | 0.0119912 |
| RPL12 | ribosomal protein L12 | 0.011912 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0118437 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0117796 |
| RPL31 | ribosomal protein L31 | 0.0115836 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0113266 |
| STX1A | syntaxin 1A (brain) | 0.0112184 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.010916 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0107801 |
| PRKCE | protein kinase C, epsilon | 0.0107624 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0106638 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0104796 |
| BEGAIN | brain-enriched guanylate kinase-associated | 0.0104565 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | 0.0103875 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.010296 |
| HLA-E | major histocompatibility complex, class I, E | 0.0101174 |
| RPL37 | ribosomal protein L37 | 0.0101087 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00987069 |
| RNF213 | ring finger protein 213 | 0.00982547 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00951009 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00937787 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.00931198 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.00924856 |
| CEP290 | centrosomal protein 290kDa | 0.00916061 |
| TMEM63A | transmembrane protein 63A | 0.00915611 |
| ZNF395 | zinc finger protein 395 | 0.00909215 |
| RPL30 | ribosomal protein L30 | 0.00903689 |
| TNS3 | tensin 3 | 0.00902152 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | 0.00899324 |
| SVIL | supervillin | 0.00893301 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00889484 |
| TDRD7 | tudor domain containing 7 | 0.008733 |
| RTTN | rotatin | 0.0086958 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.00866844 |
| PCDH1 | protocadherin 1 | 0.00863745 |
| GYS1 | glycogen synthase 1 (muscle) | 0.00855126 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.00846147 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.00819763 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00818859 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.00814939 |
| NAV1 | neuron navigator 1 | 0.0081079 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.00810275 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.308508 |
| VIM | vimentin | -0.169862 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.141979 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.139851 |
| PTMA | prothymosin, alpha | -0.13117 |
| TXNRD1 | thioredoxin reductase 1 | -0.0924436 |
| TMSB10 | thymosin beta 10 | -0.0828197 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0776564 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0681188 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0679919 |
| CANX | calnexin | -0.0649669 |
| TMSB4X | thymosin beta 4, X-linked | -0.0627564 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0614787 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0607368 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0573946 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0565852 |
| POTEF | POTE ankyrin domain family, member F | -0.0563176 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.053987 |
| APP | amyloid beta (A4) precursor protein | -0.050843 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0492958 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0486513 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0469451 |
| RAI1 | retinoic acid induced 1 | -0.0468188 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0464082 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0460334 |
| LDHA | lactate dehydrogenase A | -0.0450023 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0449597 |
| TOP1 | topoisomerase (DNA) I | -0.044938 |
| SPAG9 | sperm associated antigen 9 | -0.0426492 |
| AHNAK | AHNAK nucleoprotein | -0.0419833 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0416708 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0396156 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0374781 |
| JMJD1C | jumonji domain containing 1C | -0.0372898 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0369949 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0367668 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0367496 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0363488 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0346987 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0337479 |
| TMEM123 | transmembrane protein 123 | -0.0333464 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0325778 |
| PGK1 | phosphoglycerate kinase 1 | -0.0324938 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0316034 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0305724 |
| EREG | epiregulin | -0.030485 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0300371 |
| WASF2 | WAS protein family, member 2 | -0.0299882 |
| USP34 | ubiquitin specific peptidase 34 | -0.0299791 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0297585 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0297584 |
| GOLGA4 | golgin A4 | -0.0295494 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0293387 |
| FMNL2 | formin-like 2 | -0.0293051 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0291926 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0282715 |
| EZR | ezrin | -0.0282296 |
| RLF | rearranged L-myc fusion | -0.0281549 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0280413 |
| GLG1 | golgi glycoprotein 1 | -0.0277398 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0275247 |
| ANXA1 | annexin A1 | -0.0274674 |
| SRGN | serglycin | -0.0273586 |
| MYOF | myoferlin | -0.0273377 |
| OGA | O-GlcNAcase | -0.0271493 |
| RBM39 | RNA binding motif protein 39 | -0.0271202 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0268258 |
| TAOK1 | TAO kinase 1 | -0.0266139 |
| RAB7A | RAB7A, member RAS oncogene family | -0.026403 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0263757 |
| FNDC3B | fibronectin type III domain containing 3B | -0.026255 |
| FLNB | filamin B, beta | -0.0261056 |
| TFRC | transferrin receptor | -0.0261027 |
| ZNF292 | zinc finger protein 292 | -0.025676 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0256487 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0255377 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0255301 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0255117 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0254525 |
| CENPF | centromere protein F, 350/400kDa | -0.0252607 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0250364 |
| SBF2 | SET binding factor 2 | -0.0248674 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0246466 |
| XPO1 | exportin 1 | -0.0245769 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0245535 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.024551 |
| UBC | ubiquitin C | -0.024414 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0243143 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.024268 |
| QKI | QKI, KH domain containing, RNA binding | -0.0242289 |
| SRP54 | signal recognition particle 54kDa | -0.0241743 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0241661 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0239837 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0237068 |
| TSC22D2 | TSC22 domain family, member 2 | -0.023672 |
| FUS | FUS RNA binding protein | -0.0236126 |
| EHBP1 | EH domain binding protein 1 | -0.0235826 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0235158 |
| MAP4 | microtubule-associated protein 4 | -0.0234861 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0233839 |
