| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMAD3 | SMAD family member 3 | 0.141343 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.115969 |
| GRB10 | growth factor receptor-bound protein 10 | 0.111582 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0992139 |
| CD44 | CD44 molecule (Indian blood group) | 0.0982594 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0941104 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0898555 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0776811 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0684461 |
| NTN4 | netrin 4 | 0.0677123 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0640389 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0611149 |
| LOXL2 | lysyl oxidase-like 2 | 0.0582198 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0568345 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0565727 |
| TGM2 | transglutaminase 2 | 0.0552566 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.04856 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0481105 |
| AADAC | arylacetamide deacetylase | 0.0478311 |
| ECE1 | endothelin converting enzyme 1 | 0.0469468 |
| MYO10 | myosin X | 0.0457509 |
| NAV2 | neuron navigator 2 | 0.0437114 |
| VEGFA | vascular endothelial growth factor A | 0.0435572 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0434791 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0428884 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0420083 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0416507 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0415014 |
| PCBP2 | poly(rC) binding protein 2 | 0.0408157 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0406703 |
| KSR1 | kinase suppressor of ras 1 | 0.0405742 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0405188 |
| PKM | pyruvate kinase, muscle | 0.0401119 |
| SEPTIN9 | septin 9 | 0.0373719 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0363226 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0363212 |
| CEP250 | centrosomal protein 250kDa | 0.0361479 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0358599 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0357723 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0351402 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0350502 |
| LDHA | lactate dehydrogenase A | 0.0345395 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0343495 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0335433 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0331862 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0330814 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0330195 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0324608 |
| MCL1 | myeloid cell leukemia 1 | 0.0320576 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0318171 |
| PLEC | plectin | 0.0315765 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0313065 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0312268 |
| CDCP1 | CUB domain containing protein 1 | 0.0312201 |
| RUNX1 | runt-related transcription factor 1 | 0.0311994 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0304479 |
| SQSTM1 | sequestosome 1 | 0.0294588 |
| WLS | wntless Wnt ligand secretion mediator | 0.0291036 |
| BPTF | bromodomain PHD finger transcription factor | 0.0290172 |
| TPR | translocated promoter region, nuclear basket protein | 0.0288001 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0286577 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0282376 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0281955 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0276742 |
| RNF213 | ring finger protein 213 | 0.027597 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0272154 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.027171 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0269719 |
| ANXA2 | annexin A2 | 0.0268518 |
| ENO1 | enolase 1, (alpha) | 0.0265061 |
| RHCG | Rh family, C glycoprotein | 0.0263938 |
| ANGPTL4 | angiopoietin-like 4 | 0.0261621 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0258676 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0257354 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0256657 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0254446 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0253737 |
| FLNA | filamin A, alpha | 0.0253552 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0252345 |
| IL6ST | interleukin 6 signal transducer | 0.0251581 |
| NDRG1 | N-myc downstream regulated 1 | 0.0250936 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0249909 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.024562 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0241931 |
| UTRN | utrophin | 0.0241846 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0239937 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0239931 |
| ACTN4 | actinin, alpha 4 | 0.0236445 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0234912 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0234077 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0233707 |
| BRD2 | bromodomain containing 2 | 0.0233024 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0232448 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0231769 |
| PLIN2 | perilipin 2 | 0.0231687 |
| TGFB1 | transforming growth factor, beta 1 | 0.0229488 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0226078 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0223778 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0222235 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0221738 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.213992 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.211003 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.159565 |
| DPYD | dihydropyrimidine dehydrogenase | -0.103252 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.102515 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.102351 |
| USP34 | ubiquitin specific peptidase 34 | -0.0988029 |
| CDH13 | cadherin 13 | -0.0834758 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0826269 |
| FTL | ferritin, light polypeptide | -0.0791014 |
| RBM39 | RNA binding motif protein 39 | -0.0773257 |
| GPC6 | glypican 6 | -0.0733489 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0714411 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0689672 |
| MEF2A | myocyte enhancer factor 2A | -0.0686681 |
| NRG1 | neuregulin 1 | -0.0670484 |
| PTMA | prothymosin, alpha | -0.0661924 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0593689 |
| RAI14 | retinoic acid induced 14 | -0.0593429 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0584299 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0581226 |
| GLCCI1 | glucocorticoid induced 1 | -0.0560233 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0549826 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0531621 |
| S100A6 | S100 calcium binding protein A6 | -0.0528733 |
| ZNF804A | zinc finger protein 804A | -0.0523279 |
| RPL35A | ribosomal protein L35a | -0.0522787 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0517014 |
| OXR1 | oxidation resistance 1 | -0.0512034 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0510053 |
| AK1 | adenylate kinase 1 | -0.0500258 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0499259 |
| OSMR | oncostatin M receptor | -0.0493596 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0483466 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0482145 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0465853 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0459536 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0442774 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0437336 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0432124 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0429685 |
| CDK14 | cyclin-dependent kinase 14 | -0.0428379 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.042777 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0423632 |
| MTSS1 | metastasis suppressor 1 | -0.0423323 |
| HMGA2 | high mobility group AT-hook 2 | -0.0418782 |
| RPS21 | ribosomal protein S21 | -0.0411328 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0406839 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0402719 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0394438 |
| TMSB4X | thymosin beta 4, X-linked | -0.0391755 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0387272 |
| SETD5 | SET domain containing 5 | -0.0383863 |
| NUMB | numb homolog (Drosophila) | -0.0378608 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0376194 |
| RPS19 | ribosomal protein S19 | -0.0371876 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0371414 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0370931 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0368331 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0364319 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0363107 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0363094 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0361577 |
| PRRX1 | paired related homeobox 1 | -0.0358029 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0357632 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.035236 |
| CCDC91 | coiled-coil domain containing 91 | -0.0342607 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0341248 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0338333 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0337464 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0334679 |
| CFAP20DC | CFAP20 domain containing | -0.0334425 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0329172 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0326085 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0319841 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0319422 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0319369 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0313188 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0312633 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0308542 |
| PGK1 | phosphoglycerate kinase 1 | -0.030639 |
| TMEM165 | transmembrane protein 165 | -0.0303704 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0303293 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0302605 |
| MECOM | MDS1 and EVI1 complex locus | -0.0300234 |
| DIAPH2 | diaphanous-related formin 2 | -0.0297296 |
| VIM | vimentin | -0.0297002 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0296243 |
| RPLP2 | ribosomal protein, large, P2 | -0.0294662 |
| RPLP1 | ribosomal protein, large, P1 | -0.0291019 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.028963 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.028812 |
| NAV3 | neuron navigator 3 | -0.0286561 |
| ENOSF1 | enolase superfamily member 1 | -0.0286176 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0286126 |
| RPL34 | ribosomal protein L34 | -0.028551 |
| SYT1 | synaptotagmin I | -0.0285223 |
| NF1 | neurofibromin 1 | -0.0281946 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0281652 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0281584 |
