| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Elagolix sodium_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.161287 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.125081 |
| PM20D1 | peptidase M20 domain containing 1 | 0.113021 |
| MCL1 | myeloid cell leukemia 1 | 0.107912 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.088451 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0843316 |
| CMIP | c-Maf inducing protein | 0.0834829 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0776934 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0728804 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0685199 |
| POTEF | POTE ankyrin domain family, member F | 0.0658524 |
| WWOX | WW domain containing oxidoreductase | 0.0472072 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0471047 |
| IGF2 | insulin-like growth factor 2 | 0.0444069 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0439936 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0439173 |
| FLNA | filamin A, alpha | 0.0408783 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.040564 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0396188 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0395929 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0393542 |
| PLEC | plectin | 0.0389199 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0388247 |
| ACTN1 | actinin, alpha 1 | 0.0370865 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0370827 |
| ACTG1 | actin gamma 1 | 0.0368744 |
| EGR1 | early growth response 1 | 0.0362538 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0347287 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0346795 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.034069 |
| LAMA5 | laminin, alpha 5 | 0.0330626 |
| RAD51B | RAD51 paralog B | 0.0327723 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.032764 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0313689 |
| GLIS3 | GLIS family zinc finger 3 | 0.0306378 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0297337 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0296645 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0295552 |
| KYNU | kynureninase | 0.0292065 |
| RNF213 | ring finger protein 213 | 0.0289547 |
| HLA-C | major histocompatibility complex, class I, C | 0.0288004 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0282999 |
| PCBP2 | poly(rC) binding protein 2 | 0.0278482 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0276261 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0264796 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0264637 |
| ATP11A | ATPase, class VI, type 11A | 0.0259956 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0257951 |
| FHIT | fragile histidine triad | 0.0254225 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0246956 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0246615 |
| RPL3 | ribosomal protein L3 | 0.0246602 |
| ATXN1 | ataxin 1 | 0.0245853 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0243338 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0239588 |
| BMP6 | bone morphogenetic protein 6 | 0.0235173 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.023319 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.023319 |
| TPI1 | triosephosphate isomerase 1 | 0.0233037 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0232275 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0231907 |
| ITGB5 | integrin, beta 5 | 0.0227342 |
| MSN | moesin | 0.0224292 |
| PFN1 | profilin 1 | 0.0223323 |
| UTRN | utrophin | 0.0219927 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0219923 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0218138 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.0216493 |
| JUP | junction plakoglobin | 0.0212976 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0212335 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0210357 |
| FAT1 | FAT atypical cadherin 1 | 0.0208964 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0201549 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0200405 |
| FTO | fat mass and obesity associated | 0.0200113 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0200016 |
| NEGR1 | neuronal growth regulator 1 | 0.0198631 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0197951 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0196469 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0195615 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0192284 |
| HYOU1 | hypoxia up-regulated 1 | 0.0190775 |
| TPM3 | tropomyosin 3 | 0.0190077 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0189313 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0189192 |
| PRELID2 | PRELI domain containing 2 | 0.0188422 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0187818 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0187127 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0187106 |
| SMTN | smoothelin | 0.0183638 |
| HSPA8 | heat shock 70kDa protein 8 | 0.018296 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0181969 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0180275 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0180234 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0178957 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0178219 |
| DIAPH1 | diaphanous-related formin 1 | 0.0178027 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0177799 |
| MEF2D | myocyte enhancer factor 2D | 0.0175962 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0175841 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.29058 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.268637 |
| PTMA | prothymosin, alpha | -0.105593 |
| VIM | vimentin | -0.0972017 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0809917 |
| IER3 | immediate early response 3 | -0.079207 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0777914 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0771971 |
| FTL | ferritin, light polypeptide | -0.0745682 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0707023 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0702449 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.065146 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0625256 |
| RPL19 | ribosomal protein L19 | -0.0624993 |
| RBM39 | RNA binding motif protein 39 | -0.0604046 |
| CAVIN1 | caveolae associated protein 1 | -0.0596969 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0572186 |
| TXNRD1 | thioredoxin reductase 1 | -0.0541674 |
| RPS8 | ribosomal protein S8 | -0.048917 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0483225 |
| S100A10 | S100 calcium binding protein A10 | -0.0474207 |
| RPS2 | ribosomal protein S2 | -0.0473784 |
| RPS27A | ribosomal protein S27a | -0.0470397 |
| RAD21 | RAD21 homolog (S. pombe) | -0.045027 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0441489 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0437882 |
| RPS6 | ribosomal protein S6 | -0.0411557 |
| NOP58 | NOP58 ribonucleoprotein | -0.039538 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0388853 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0388671 |
| S100A6 | S100 calcium binding protein A6 | -0.0385127 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.038495 |
| RPL31 | ribosomal protein L31 | -0.0372189 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0364954 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0358371 |
| RPS24 | ribosomal protein S24 | -0.0353014 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0351837 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0347878 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0343389 |
| RPL26 | ribosomal protein L26 | -0.0342458 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0339461 |
| RPS25 | ribosomal protein S25 | -0.0331442 |
| APP | amyloid beta (A4) precursor protein | -0.0327587 |
| CANX | calnexin | -0.032707 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0325507 |
| RPL4 | ribosomal protein L4 | -0.0324118 |
| GOLT1B | golgi transport 1B | -0.0320849 |
| SRGN | serglycin | -0.0318274 |
| RPL7 | ribosomal protein L7 | -0.030928 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0307605 |
| DENND4A | DENN/MADD domain containing 4A | -0.0301859 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0295559 |
| RPS23 | ribosomal protein S23 | -0.0294136 |
| RPL38 | ribosomal protein L38 | -0.0293562 |
| SEPTIN7 | septin 7 | -0.0292959 |
| RPS29 | ribosomal protein S29 | -0.0291564 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0289816 |
| STC1 | stanniocalcin 1 | -0.0288194 |
| RAB10 | RAB10, member RAS oncogene family | -0.0285932 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0279833 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0279696 |
| CFDP1 | craniofacial development protein 1 | -0.0274399 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0274195 |
| MORF4L1 | mortality factor 4 like 1 | -0.0268125 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0263969 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0260436 |
| ATXN3 | ataxin 3 | -0.0260169 |
| HDAC9 | histone deacetylase 9 | -0.0258833 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0257608 |
| KIF5B | kinesin family member 5B | -0.0256369 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0256293 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0255867 |
| RPL9 | ribosomal protein L9 | -0.0249819 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0248 |
| TNPO1 | transportin 1 | -0.0242795 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0240992 |
| SERF2 | small EDRK-rich factor 2 | -0.0240372 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0238728 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0237021 |
| RPS16 | ribosomal protein S16 | -0.0235964 |
| RPL37A | ribosomal protein L37a | -0.0235741 |
| RPLP0 | ribosomal protein, large, P0 | -0.0235383 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0234952 |
| SHTN1 | shootin 1 | -0.0232539 |
| ZFR | zinc finger RNA binding protein | -0.0232168 |
| RAN | RAN, member RAS oncogene family | -0.0232134 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0231718 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0229799 |
| TPD52 | tumor protein D52 | -0.0228325 |
| RPL6 | ribosomal protein L6 | -0.0228034 |
| ZNF292 | zinc finger protein 292 | -0.0228013 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0227305 |
| PFDN2 | prefoldin subunit 2 | -0.0224929 |
| RTN4 | reticulon 4 | -0.0224842 |
| RPS5 | ribosomal protein S5 | -0.0224283 |
| RPLP1 | ribosomal protein, large, P1 | -0.0224027 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0223686 |
| RPS15 | ribosomal protein S15 | -0.0222023 |
| RPL34 | ribosomal protein L34 | -0.0221337 |
| RPS12 | ribosomal protein S12 | -0.0221205 |
