| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.280008 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.109669 |
| MCL1 | myeloid cell leukemia 1 | 0.0975591 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.091376 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0668619 |
| HSPA8 | heat shock 70kDa protein 8 | 0.065307 |
| PLEC | plectin | 0.06202 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0569703 |
| ACTG1 | actin gamma 1 | 0.0565798 |
| TPM3 | tropomyosin 3 | 0.0563437 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0439259 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0436293 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0414389 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0407427 |
| FLNA | filamin A, alpha | 0.0405516 |
| BRD2 | bromodomain containing 2 | 0.0392339 |
| CEP250 | centrosomal protein 250kDa | 0.0388637 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0362542 |
| RPL3 | ribosomal protein L3 | 0.0360653 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0331679 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0327762 |
| INTS6 | integrator complex subunit 6 | 0.0322397 |
| AEBP2 | AE binding protein 2 | 0.0321126 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0316721 |
| HLA-C | major histocompatibility complex, class I, C | 0.0316432 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0311435 |
| KRT18 | keratin 18, type I | 0.030629 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0289489 |
| PRKCE | protein kinase C, epsilon | 0.0286317 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0285828 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0280454 |
| TLN1 | talin 1 | 0.027654 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0273751 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0272356 |
| DSPP | dentin sialophosphoprotein | 0.0269625 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0268532 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0264972 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0264844 |
| ACTN1 | actinin, alpha 1 | 0.0262788 |
| HOMER1 | homer scaffolding protein 1 | 0.0255553 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0253414 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0249859 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0245769 |
| CMIP | c-Maf inducing protein | 0.0240574 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0237523 |
| HMOX1 | heme oxygenase 1 | 0.0237415 |
| EGR1 | early growth response 1 | 0.0236414 |
| RBM19 | RNA binding motif protein 19 | 0.023612 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0226245 |
| SEPTIN9 | septin 9 | 0.021164 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0204872 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0204095 |
| GOLGB1 | golgin B1 | 0.0200592 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0199844 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0199583 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0196821 |
| WWOX | WW domain containing oxidoreductase | 0.0193446 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0191672 |
| HDAC4 | histone deacetylase 4 | 0.0190097 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.018947 |
| YBX1 | Y box binding protein 1 | 0.0189315 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0188632 |
| RPS3 | ribosomal protein S3 | 0.0188135 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.018795 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0184145 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.018355 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0181165 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.017992 |
| CTTN | cortactin | 0.0176121 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0175521 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0175269 |
| CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | 0.0174275 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0170539 |
| SET | SET nuclear proto-oncogene | 0.0169557 |
| PABPC1L | poly(A) binding protein, cytoplasmic 1-like | 0.0169497 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0167703 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0166837 |
| PRELID2 | PRELI domain containing 2 | 0.0166316 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0165565 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.016547 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0163929 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0163695 |
| DST | dystonin | 0.0162052 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0160279 |
| TPM2 | tropomyosin 2 (beta) | 0.0158544 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.0158279 |
| AMOTL2 | angiomotin like 2 | 0.0157948 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0157553 |
| TPI1 | triosephosphate isomerase 1 | 0.0156943 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0156095 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0154127 |
| LOXL2 | lysyl oxidase-like 2 | 0.0153639 |
| NEK10 | NIMA-related kinase 10 | 0.0152785 |
| KIF1A | kinesin family member 1A | 0.0151618 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | 0.0150773 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0150376 |
| FERMT2 | fermitin family member 2 | 0.0149393 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0148709 |
| MSN | moesin | 0.0148567 |
| CCDC200 | coiled-coil domain containing 200 | 0.014805 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.318606 |
| PTMA | prothymosin, alpha | -0.10941 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0903711 |
| TMSB10 | thymosin beta 10 | -0.0779955 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0773615 |
| VIM | vimentin | -0.06774 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0643796 |
| RBM39 | RNA binding motif protein 39 | -0.064197 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.06413 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.063383 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0572202 |
| TXNRD1 | thioredoxin reductase 1 | -0.0560088 |
| ZFR | zinc finger RNA binding protein | -0.0552988 |
| USP34 | ubiquitin specific peptidase 34 | -0.0539661 |
| RPS21 | ribosomal protein S21 | -0.0531616 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0526699 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0510341 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0499424 |
| BBX | bobby sox homolog (Drosophila) | -0.0481281 |
| OSMR | oncostatin M receptor | -0.0469636 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0453928 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0438706 |
| SBF2 | SET binding factor 2 | -0.0427696 |
| PHIP | pleckstrin homology domain interacting protein | -0.0422126 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0418048 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0417321 |
| TMEM165 | transmembrane protein 165 | -0.0413968 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0410817 |
| NF1 | neurofibromin 1 | -0.0407294 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0398188 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0396892 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0393888 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0393412 |
| WASF2 | WAS protein family, member 2 | -0.0392802 |
| RPS24 | ribosomal protein S24 | -0.039126 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0384625 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0382446 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0370267 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0366798 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0362998 |
| LATS2 | large tumor suppressor kinase 2 | -0.0356632 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0354069 |
| ZNF292 | zinc finger protein 292 | -0.035229 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.035107 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0350328 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0350096 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0348256 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0347888 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0342968 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0340917 |
| RPS8 | ribosomal protein S8 | -0.0340726 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0338136 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0337221 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0335211 |
| SETD5 | SET domain containing 5 | -0.0334997 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0333134 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0329333 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0329204 |
| CD2AP | CD2-associated protein | -0.0328626 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0327174 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0326156 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0324955 |
| RPS15 | ribosomal protein S15 | -0.0321503 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0317116 |
| MAP4 | microtubule-associated protein 4 | -0.0314393 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0313205 |
| XPO1 | exportin 1 | -0.031248 |
| CCDC91 | coiled-coil domain containing 91 | -0.031244 |
| RPS27A | ribosomal protein S27a | -0.031164 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0311579 |
| TNPO3 | transportin 3 | -0.03115 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0308091 |
| PGK1 | phosphoglycerate kinase 1 | -0.0308046 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.030681 |
| RTN4 | reticulon 4 | -0.0305946 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.030523 |
| PHF20 | PHD finger protein 20 | -0.0303814 |
| FBXO11 | F-box protein 11 | -0.0303699 |
| RPLP0 | ribosomal protein, large, P0 | -0.0301928 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0301571 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0298963 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0298762 |
| RPL26 | ribosomal protein L26 | -0.0297894 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0297771 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0297697 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0297424 |
| OGA | O-GlcNAcase | -0.0297307 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0297019 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0295677 |
| TLK1 | tousled-like kinase 1 | -0.0295589 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0293429 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0292026 |
| GOLGA4 | golgin A4 | -0.0291612 |
| RBM25 | RNA binding motif protein 25 | -0.0290148 |
| RPL35A | ribosomal protein L35a | -0.0289532 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0287846 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0284157 |
| COG5 | component of oligomeric golgi complex 5 | -0.0281453 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0281305 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0279218 |
