| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Elagolix sodium_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.102913 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0339379 |
| RPS3 | ribosomal protein S3 | 0.0322332 |
| RPL37A | ribosomal protein L37a | 0.0296122 |
| ACTG1 | actin gamma 1 | 0.0287489 |
| PLEC | plectin | 0.0270119 |
| RPS12 | ribosomal protein S12 | 0.0270055 |
| RPL37 | ribosomal protein L37 | 0.026995 |
| SMAD3 | SMAD family member 3 | 0.0263814 |
| RPS17 | ribosomal protein S17 | 0.0261503 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0253728 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0245538 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0245102 |
| HLA-C | major histocompatibility complex, class I, C | 0.024458 |
| HLA-B | major histocompatibility complex, class I, B | 0.0241349 |
| PLSCR1 | phospholipid scramblase 1 | 0.0219638 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0217395 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0217382 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0215118 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0204635 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0203618 |
| RPL35A | ribosomal protein L35a | 0.0203025 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0202901 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0200731 |
| RACK1 | receptor for activated C kinase 1 | 0.0193552 |
| RPL13A | ribosomal protein L13a | 0.0193413 |
| RPL41 | ribosomal protein L41 | 0.0192121 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0189511 |
| AFDN | afadin, adherens junction formation factor | 0.0181411 |
| RPS27A | ribosomal protein S27a | 0.0179484 |
| ARRDC3 | arrestin domain containing 3 | 0.016499 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0164541 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0160272 |
| RPS18 | ribosomal protein S18 | 0.015792 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0157058 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.015696 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0156742 |
| RPL27 | ribosomal protein L27 | 0.0155071 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0153672 |
| MYO5B | myosin VB | 0.0153417 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.015084 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0146897 |
| CDK13 | cyclin-dependent kinase 13 | 0.0145385 |
| MAPK14 | mitogen-activated protein kinase 14 | 0.0144688 |
| ASS1 | argininosuccinate synthase 1 | 0.0143899 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0142152 |
| JAK1 | Janus kinase 1 | 0.0138657 |
| SVIL | supervillin | 0.013753 |
| FLNA | filamin A, alpha | 0.0136387 |
| RPS8 | ribosomal protein S8 | 0.013557 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0132492 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0130746 |
| ATP11A | ATPase, class VI, type 11A | 0.0128553 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0126277 |
| TDRD7 | tudor domain containing 7 | 0.0125785 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 | 0.0125488 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0123723 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0123195 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.0122922 |
| CUL4A | cullin 4A | 0.012096 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0120869 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0118549 |
| RPL10A | ribosomal protein L10a | 0.0117353 |
| RPL12 | ribosomal protein L12 | 0.0115734 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0115721 |
| RPL34 | ribosomal protein L34 | 0.0113971 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0113846 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0109549 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0109154 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.01086 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.010795 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0107754 |
| STK10 | serine/threonine kinase 10 | 0.0107435 |
| CEP250 | centrosomal protein 250kDa | 0.0107421 |
| PATJ | PATJ crumbs cell polarity complex component | 0.010618 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0106129 |
| ELAVL1 | ELAV like RNA binding protein 1 | 0.0105217 |
| DAPK1 | death-associated protein kinase 1 | 0.0103074 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0102037 |
| RPL26 | ribosomal protein L26 | 0.0101477 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0101336 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0100946 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0100258 |
| GTPBP2 | GTP binding protein 2 | 0.00998868 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0099277 |
| PMM2 | phosphomannomutase 2 | 0.00986812 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00983076 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.00979781 |
| APP | amyloid beta (A4) precursor protein | 0.00978503 |
| VEGFA | vascular endothelial growth factor A | 0.00962801 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.00960069 |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C | 0.00952494 |
| DENND1A | DENN/MADD domain containing 1A | 0.00952359 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0094203 |
| RPS27 | ribosomal protein S27 | 0.00927641 |
| SIN3B | SIN3 transcription regulator family member B | 0.00922736 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.00913123 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.00912713 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | 0.00909978 |
| FZD6 | frizzled class receptor 6 | 0.00907581 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.49336 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.141569 |
| PTMA | prothymosin, alpha | -0.125087 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.122111 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0839416 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.083905 |
| HMGA1 | high mobility group AT-hook 1 | -0.0837385 |
| TMSB10 | thymosin beta 10 | -0.082062 |
| LDHA | lactate dehydrogenase A | -0.077149 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0765913 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0714889 |
| CCNL1 | cyclin L1 | -0.0663322 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0661663 |
| POTEF | POTE ankyrin domain family, member F | -0.0655111 |
| EMP1 | epithelial membrane protein 1 | -0.0645211 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0641376 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.05928 |
| RPS6 | ribosomal protein S6 | -0.0581357 |
| LAMA4 | laminin, alpha 4 | -0.0579867 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0575896 |
| KRT19 | keratin 19, type I | -0.0570962 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0564283 |
| EZR | ezrin | -0.0556872 |
| FAM3C | family with sequence similarity 3, member C | -0.054865 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0514907 |
| RBM39 | RNA binding motif protein 39 | -0.0506633 |
| FOSL1 | FOS-like antigen 1 | -0.0504067 |
| TMEM123 | transmembrane protein 123 | -0.0502925 |
| B2M | beta-2-microglobulin | -0.0494912 |
| TXNIP | thioredoxin interacting protein | -0.049463 |
| ANLN | anillin, actin binding protein | -0.0489671 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0488428 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0476672 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0470712 |
| CANX | calnexin | -0.045539 |
| PGK1 | phosphoglycerate kinase 1 | -0.0454658 |
| PCBP2 | poly(rC) binding protein 2 | -0.0450274 |
| PKM | pyruvate kinase, muscle | -0.0434269 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0429949 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0425319 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0422969 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0422359 |
| S100A10 | S100 calcium binding protein A10 | -0.0420186 |
| MKI67 | marker of proliferation Ki-67 | -0.0416262 |
| NDRG1 | N-myc downstream regulated 1 | -0.0413824 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0409066 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0404558 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0401843 |
| CD2AP | CD2-associated protein | -0.0392646 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0391795 |
| KRT8 | keratin 8, type II | -0.0390791 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0386047 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0385535 |
| RPS15 | ribosomal protein S15 | -0.0384841 |
| MYO6 | myosin VI | -0.0383955 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0383887 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0383528 |
| GOLGA4 | golgin A4 | -0.0375712 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0367736 |
| C3 | complement component 3 | -0.0366524 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0365303 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0363312 |
| ECT2 | epithelial cell transforming 2 | -0.0361014 |
| CENPF | centromere protein F, 350/400kDa | -0.0355579 |
| EHF | ets homologous factor | -0.0355238 |
| RPS24 | ribosomal protein S24 | -0.0353964 |
| RPS23 | ribosomal protein S23 | -0.0350318 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0348605 |
| EGR1 | early growth response 1 | -0.0347407 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0345239 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0343172 |
| YBX3 | Y box binding protein 3 | -0.0342878 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0341331 |
| RLF | rearranged L-myc fusion | -0.0340938 |
| RIOK3 | RIO kinase 3 | -0.0335237 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0331347 |
| DIAPH3 | diaphanous-related formin 3 | -0.0331323 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0328603 |
| TGM2 | transglutaminase 2 | -0.0325215 |
| VIM | vimentin | -0.0325083 |
| H3-3B | H3.3 histone B | -0.032287 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0321783 |
| AHNAK | AHNAK nucleoprotein | -0.0320255 |
| ANXA2 | annexin A2 | -0.0319872 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0317542 |
| TPI1 | triosephosphate isomerase 1 | -0.0313455 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0308888 |
| CDCP1 | CUB domain containing protein 1 | -0.030861 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0307116 |
| PLAU | plasminogen activator, urokinase | -0.0306818 |
| RPL28 | ribosomal protein L28 | -0.0305813 |
| KRT18 | keratin 18, type I | -0.0305735 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0304779 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0304021 |
| WWC1 | WW and C2 domain containing 1 | -0.0303973 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0297525 |
| SPAG9 | sperm associated antigen 9 | -0.029748 |
| UBC | ubiquitin C | -0.0297245 |
| PTK2 | protein tyrosine kinase 2 | -0.0297099 |
| SETD5 | SET domain containing 5 | -0.0296122 |
