| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD6 | FERM domain containing 6 | 0.146893 |
| FLNB | filamin B, beta | 0.146061 |
| ACTG1 | actin gamma 1 | 0.144656 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.126131 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.111512 |
| ZNF438 | zinc finger protein 438 | 0.088971 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0795779 |
| LAMB3 | laminin, beta 3 | 0.0789007 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0787066 |
| FRMD4A | FERM domain containing 4A | 0.0744379 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0733523 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0603777 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0582883 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0561809 |
| FLNA | filamin A, alpha | 0.0550101 |
| NAV2 | neuron navigator 2 | 0.0537529 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 0.0516554 |
| MCL1 | myeloid cell leukemia 1 | 0.0515775 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0505986 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0476017 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0474056 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0467927 |
| HMGA2 | high mobility group AT-hook 2 | 0.0462451 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0455916 |
| TPM4 | tropomyosin 4 | 0.0455125 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0424036 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0412126 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0399047 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0395455 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0388196 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0371801 |
| RAD51B | RAD51 paralog B | 0.0358122 |
| RGS4 | regulator of G-protein signaling 4 | 0.0351294 |
| MTDH | metadherin | 0.0339509 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0336699 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0332795 |
| SET | SET nuclear proto-oncogene | 0.0327823 |
| DST | dystonin | 0.0324206 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.0322877 |
| CEP250 | centrosomal protein 250kDa | 0.0319493 |
| RRM2 | ribonucleotide reductase M2 | 0.0316816 |
| ANXA2 | annexin A2 | 0.0309299 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0307315 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0300979 |
| RNF213 | ring finger protein 213 | 0.0297802 |
| SMTN | smoothelin | 0.0293525 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0293404 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0293302 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0292051 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0291871 |
| EFNB2 | ephrin-B2 | 0.0289289 |
| DEK | DEK proto-oncogene | 0.0289089 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0288101 |
| SQSTM1 | sequestosome 1 | 0.0283167 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0280746 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0277505 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0274458 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0270788 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0259658 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0254544 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0246566 |
| ENO1 | enolase 1, (alpha) | 0.0246332 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0243899 |
| TRIM44 | tripartite motif containing 44 | 0.0242749 |
| SURF4 | surfeit 4 | 0.0241723 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0235655 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0234025 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0230698 |
| NUDC | nudC nuclear distribution protein | 0.0222932 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.0222505 |
| JUN | jun proto-oncogene | 0.0220802 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0220399 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.0218083 |
| RACK1 | receptor for activated C kinase 1 | 0.0217928 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0217346 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0213108 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | 0.0210279 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.021021 |
| STC1 | stanniocalcin 1 | 0.020968 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0208169 |
| RPS4X | ribosomal protein S4, X-linked | 0.020739 |
| PRKCE | protein kinase C, epsilon | 0.0207205 |
| FKBP15 | FK506 binding protein 15, 133kDa | 0.0206959 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.0206664 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0205425 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0204638 |
| ADTRP | androgen-dependent TFPI-regulating protein | 0.0204053 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.0200558 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0199525 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0198432 |
| ARHGAP39 | Rho GTPase activating protein 39 | 0.0196377 |
| CMIP | c-Maf inducing protein | 0.0196338 |
| HDLBP | high density lipoprotein binding protein | 0.0195761 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.0195743 |
| MAPK13 | mitogen-activated protein kinase 13 | 0.0195102 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0194941 |
| SLFN5 | schlafen family member 5 | 0.0192332 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0190764 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0189865 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | 0.0189098 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.147185 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0695639 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0659404 |
| ZNF292 | zinc finger protein 292 | -0.0590847 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.05356 |
| PTK2 | protein tyrosine kinase 2 | -0.0526618 |
| SBF2 | SET binding factor 2 | -0.0509834 |
| RBM39 | RNA binding motif protein 39 | -0.0492174 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0487711 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0486885 |
| TMSB10 | thymosin beta 10 | -0.0479659 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0474686 |
| JMJD1C | jumonji domain containing 1C | -0.0458795 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0450924 |
| ATP13A3 | ATPase type 13A3 | -0.0428909 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0425896 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0420479 |
| DIAPH3 | diaphanous-related formin 3 | -0.0408885 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0404758 |
| RPL26 | ribosomal protein L26 | -0.0397923 |
| TTR | transthyretin | -0.0396994 |
| CCNL1 | cyclin L1 | -0.0395031 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0394201 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0389725 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0388136 |
| SETD5 | SET domain containing 5 | -0.0385987 |
| PGK1 | phosphoglycerate kinase 1 | -0.0377944 |
| MT2A | metallothionein 2A | -0.0376685 |
| NUP58 | nucleoporin 58 | -0.0374067 |
| RPL9 | ribosomal protein L9 | -0.0367123 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0366844 |
| RPS21 | ribosomal protein S21 | -0.0360872 |
| PKM | pyruvate kinase, muscle | -0.0359334 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0359287 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0356591 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.035633 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0354413 |
| POTEF | POTE ankyrin domain family, member F | -0.0346918 |
| FOXJ3 | forkhead box J3 | -0.0344351 |
| USP34 | ubiquitin specific peptidase 34 | -0.0339276 |
| COG5 | component of oligomeric golgi complex 5 | -0.0334936 |
| PTMA | prothymosin, alpha | -0.0333836 |
| RPS15 | ribosomal protein S15 | -0.0330428 |
| NKTR | natural killer cell triggering receptor | -0.0322488 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0320368 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0308898 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0307215 |
| USP3 | ubiquitin specific peptidase 3 | -0.0306953 |
| RPL32 | ribosomal protein L32 | -0.0303632 |
| TRAM1 | translocation associated membrane protein 1 | -0.0300997 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0299087 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0298698 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0297251 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0296528 |
| RPS2 | ribosomal protein S2 | -0.0290968 |
| BRD4 | bromodomain containing 4 | -0.0290606 |
| CDC73 | cell division cycle 73 | -0.0288811 |
| RLF | rearranged L-myc fusion | -0.0287862 |
| RPS24 | ribosomal protein S24 | -0.0287382 |
| RBM25 | RNA binding motif protein 25 | -0.0286397 |
| TFG | TRK-fused gene | -0.0285109 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0284915 |
| NF1 | neurofibromin 1 | -0.0284265 |
| SRPK2 | SRSF protein kinase 2 | -0.0281325 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0280331 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0279603 |
| RPLP2 | ribosomal protein, large, P2 | -0.0278883 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.027551 |
| RPL28 | ribosomal protein L28 | -0.0275023 |
| SPAG9 | sperm associated antigen 9 | -0.0274465 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0273722 |
| DENND4A | DENN/MADD domain containing 4A | -0.0271783 |
| RPL19 | ribosomal protein L19 | -0.0269885 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0267861 |
| CLTC | clathrin, heavy chain (Hc) | -0.026622 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0265859 |
| ECT2 | epithelial cell transforming 2 | -0.0263871 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0262704 |
| TXNRD1 | thioredoxin reductase 1 | -0.0262487 |
| RHEB | Ras homolog enriched in brain | -0.0261483 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0261427 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0260222 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0259969 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0259179 |
| RPL5 | ribosomal protein L5 | -0.0258279 |
| EVI5 | ecotropic viral integration site 5 | -0.0257367 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0257367 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0253851 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0253386 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0249405 |
| MTAP | methylthioadenosine phosphorylase | -0.0248672 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0246636 |
| CANX | calnexin | -0.0246629 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0242821 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0242395 |
| HELZ | helicase with zinc finger | -0.0241639 |
| RPL21 | ribosomal protein L21 | -0.0240742 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0240687 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0240185 |
| LDHA | lactate dehydrogenase A | -0.0239247 |
