| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0683318 |
| VEGFA | vascular endothelial growth factor A | 0.0583512 |
| HDAC9 | histone deacetylase 9 | 0.0374066 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0362197 |
| ASPH | aspartate beta-hydroxylase | 0.0330604 |
| PLEC | plectin | 0.0306086 |
| SMAD3 | SMAD family member 3 | 0.0270323 |
| FHIT | fragile histidine triad | 0.025765 |
| NAV1 | neuron navigator 1 | 0.0255166 |
| MSN | moesin | 0.0251586 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.02499 |
| MCL1 | myeloid cell leukemia 1 | 0.0248477 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.024294 |
| TMEM178B | transmembrane protein 178B | 0.023439 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0222883 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0222703 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0222221 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0217283 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0216052 |
| COL5A1 | collagen, type V, alpha 1 | 0.0215891 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0211178 |
| RNF213 | ring finger protein 213 | 0.0209412 |
| AGRN | agrin | 0.020739 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0205962 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0205891 |
| INTS6 | integrator complex subunit 6 | 0.0205488 |
| IFI44L | interferon-induced protein 44-like | 0.0205057 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0203453 |
| KYNU | kynureninase | 0.0197263 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0189772 |
| ANGPTL4 | angiopoietin-like 4 | 0.0188947 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0188842 |
| HPCAL1 | hippocalcin-like 1 | 0.0188801 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0188652 |
| EGR1 | early growth response 1 | 0.0181149 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0181077 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0179633 |
| FAT1 | FAT atypical cadherin 1 | 0.0178581 |
| GLIS3 | GLIS family zinc finger 3 | 0.0173475 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0169127 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0167882 |
| SETBP1 | SET binding protein 1 | 0.0167013 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | 0.0163668 |
| HSPA8 | heat shock 70kDa protein 8 | 0.016253 |
| DNHD1 | dynein heavy chain domain 1 | 0.0160761 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0157024 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0154539 |
| SHISA5 | shisa family member 5 | 0.0151906 |
| EXOC6B | exocyst complex component 6B | 0.0151422 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0151012 |
| ARRDC3 | arrestin domain containing 3 | 0.0149371 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0148984 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0147916 |
| COL5A3 | collagen, type V, alpha 3 | 0.0147288 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0146442 |
| HMGA2 | high mobility group AT-hook 2 | 0.0145587 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.0144932 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0144151 |
| TGM2 | transglutaminase 2 | 0.0141573 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0141493 |
| RPS17 | ribosomal protein S17 | 0.0137266 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0136554 |
| HOMER1 | homer scaffolding protein 1 | 0.0135714 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0134345 |
| DGKI | diacylglycerol kinase, iota | 0.0130721 |
| CCN4 | cellular communication network factor 4 | 0.0130456 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0130054 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0127877 |
| FOSL1 | FOS-like antigen 1 | 0.0127765 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0126652 |
| TPM3 | tropomyosin 3 | 0.0126579 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0125853 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0124459 |
| ATXN1 | ataxin 1 | 0.012414 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0123636 |
| FLNA | filamin A, alpha | 0.0123087 |
| NABP1 | nucleic acid binding protein 1 | 0.0122992 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0122316 |
| EXOSC3 | exosome component 3 | 0.0121663 |
| TAPBP | TAP binding protein (tapasin) | 0.0121607 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.012071 |
| SMYD3 | SET and MYND domain containing 3 | 0.011977 |
| SMOX | spermine oxidase | 0.0119439 |
| CSMD2 | CUB and Sushi multiple domains 2 | 0.0118173 |
| CFAP44 | cilia and flagella associated protein 44 | 0.011809 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0118039 |
| LINC02798 | long intergenic non-protein coding RNA 2798 | 0.0117749 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0116576 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0116088 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0115989 |
| FAM219A | family with sequence similarity 219, member A | 0.0115605 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.011335 |
| IPO9 | importin 9 | 0.0112976 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0112666 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.0112416 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0111602 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0111399 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0111333 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0109269 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0109045 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.367063 |
| FN1 | fibronectin 1 | -0.231144 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.193038 |
| COL1A1 | collagen, type I, alpha 1 | -0.153476 |
| COL1A2 | collagen, type I, alpha 2 | -0.137167 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.133509 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.131036 |
| PGK1 | phosphoglycerate kinase 1 | -0.127937 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.116955 |
| HLA-B | major histocompatibility complex, class I, B | -0.0974211 |
| PTMA | prothymosin, alpha | -0.0942997 |
| GOLGA4 | golgin A4 | -0.0861674 |
| TPM4 | tropomyosin 4 | -0.0719064 |
| FTL | ferritin, light polypeptide | -0.0682031 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0677122 |
| TMSB10 | thymosin beta 10 | -0.0569545 |
| RRBP1 | ribosome binding protein 1 | -0.0557431 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0534691 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0529336 |
| GNAS | GNAS complex locus | -0.0521192 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0519718 |
| IER3 | immediate early response 3 | -0.0479947 |
| CALU | calumenin | -0.0479697 |
| MMP12 | matrix metallopeptidase 12 | -0.0461995 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0445942 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0435695 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0434777 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0433952 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0420046 |
| CALR | calreticulin | -0.041555 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0415434 |
| PKM | pyruvate kinase, muscle | -0.0411137 |
| ZNF292 | zinc finger protein 292 | -0.0402558 |
| LDHA | lactate dehydrogenase A | -0.0402546 |
| MT2A | metallothionein 2A | -0.0402393 |
| RPS6 | ribosomal protein S6 | -0.0395296 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0394762 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0386798 |
| CD44 | CD44 molecule (Indian blood group) | -0.0383078 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0380624 |
| SEPTIN7 | septin 7 | -0.0380582 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0378686 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0375821 |
| RBM39 | RNA binding motif protein 39 | -0.0374246 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0371303 |
| B2M | beta-2-microglobulin | -0.0368034 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0367149 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0363768 |
| CD109 | CD109 molecule | -0.0363209 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0359042 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0357044 |
| S100A6 | S100 calcium binding protein A6 | -0.0355386 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0355196 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0354931 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0349779 |
| CANX | calnexin | -0.0349592 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0347723 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0344782 |
| MEF2A | myocyte enhancer factor 2A | -0.0331561 |
| MAP4 | microtubule-associated protein 4 | -0.0329555 |
| ENO1 | enolase 1, (alpha) | -0.0327538 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0327203 |
| TPM1 | tropomyosin 1 (alpha) | -0.032681 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0324947 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.031878 |
| S100A10 | S100 calcium binding protein A10 | -0.0318732 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0318061 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0316526 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0316296 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0315627 |
| H1-0 | H1.0 linker histone | -0.0315241 |
| SETD5 | SET domain containing 5 | -0.0314835 |
| ANXA2 | annexin A2 | -0.031239 |
| NRP1 | neuropilin 1 | -0.0311802 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0310962 |
| FNDC3B | fibronectin type III domain containing 3B | -0.03075 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0305559 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0300084 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0298223 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0293501 |
| LMNA | lamin A/C | -0.0293065 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0289094 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0288436 |
| FAM162A | family with sequence similarity 162, member A | -0.0285107 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0284661 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0284186 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0283187 |
| STC1 | stanniocalcin 1 | -0.0282212 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0281969 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0281104 |
| MORF4L1 | mortality factor 4 like 1 | -0.0279227 |
| TNNC1 | troponin C type 1 (slow) | -0.0278396 |
| INHBA | inhibin, beta A | -0.0277839 |
| ATP13A3 | ATPase type 13A3 | -0.0275412 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0275267 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0274008 |
| CAVIN1 | caveolae associated protein 1 | -0.0272251 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0270825 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0269587 |
| RLF | rearranged L-myc fusion | -0.0269108 |
