| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MCL1 | myeloid cell leukemia 1 | 0.0962264 |
| NRG1 | neuregulin 1 | 0.0884508 |
| ACTG1 | actin gamma 1 | 0.0817277 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | 0.072264 |
| INHBA | inhibin, beta A | 0.0663155 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0635568 |
| GPC6 | glypican 6 | 0.057488 |
| STC1 | stanniocalcin 1 | 0.0570025 |
| SNTG1 | syntrophin, gamma 1 | 0.0546778 |
| NBEA | neurobeachin | 0.0525476 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0522748 |
| EGR1 | early growth response 1 | 0.0512918 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0509522 |
| KIF26B | kinesin family member 26B | 0.0491393 |
| PAEP | progestagen-associated endometrial protein | 0.0484324 |
| RNF213 | ring finger protein 213 | 0.0458814 |
| VGF | VGF nerve growth factor inducible | 0.0435657 |
| RORA | RAR-related orphan receptor A | 0.0414302 |
| COL22A1 | collagen, type XXII, alpha 1 | 0.0409748 |
| NCKAP5 | NCK-associated protein 5 | 0.0398916 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0391929 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | 0.0391681 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0385187 |
| NAV2 | neuron navigator 2 | 0.0384079 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.0382867 |
| CNKSR3 | CNKSR family member 3 | 0.037562 |
| CHGB | chromogranin B | 0.0370626 |
| PTCHD4 | patched domain containing 4 | 0.0368148 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0354321 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0353127 |
| SMYD3 | SET and MYND domain containing 3 | 0.0345382 |
| ASIC2 | acid sensing (proton gated) ion channel 2 | 0.0337997 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0332633 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.0324566 |
| SVIL | supervillin | 0.032349 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.0318537 |
| GPC5 | glypican 5 | 0.0309359 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.030754 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.0299957 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0295319 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0294852 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0292279 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0287865 |
| HSPA8 | heat shock 70kDa protein 8 | 0.027048 |
| NDRG1 | N-myc downstream regulated 1 | 0.0269978 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0267673 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0266086 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.026227 |
| TRAPPC12 | trafficking protein particle complex 12 | 0.0261231 |
| NELL1 | NEL-like 1 (chicken) | 0.0248718 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0248558 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0248499 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0239488 |
| INTS6 | integrator complex subunit 6 | 0.0239451 |
| KLHL29 | kelch-like family member 29 | 0.0238061 |
| WWOX | WW domain containing oxidoreductase | 0.0236631 |
| TOX | thymocyte selection-associated high mobility group box | 0.0234798 |
| EFNA5 | ephrin-A5 | 0.0232334 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0230041 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0225186 |
| SQSTM1 | sequestosome 1 | 0.0223688 |
| SP100 | SP100 nuclear antigen | 0.0222659 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0220171 |
| SCG2 | secretogranin II | 0.0219969 |
| SMAD3 | SMAD family member 3 | 0.0217969 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0212843 |
| RGS17 | regulator of G-protein signaling 17 | 0.0211142 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0209937 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.020953 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0209457 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.0209319 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0204544 |
| HOMER1 | homer scaffolding protein 1 | 0.0204423 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0203665 |
| RIGI | RNA sensor RIG-I | 0.0203487 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.0201814 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0200544 |
| SATB2 | SATB homeobox 2 | 0.0199336 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0197909 |
| GPATCH2L | G patch domain containing 2-like | 0.0197831 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | 0.0197474 |
| EGFR | epidermal growth factor receptor | 0.0197155 |
| PALLD | palladin, cytoskeletal associated protein | 0.0195878 |
| SETX | senataxin | 0.0195058 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0192964 |
| JUN | jun proto-oncogene | 0.0192621 |
| LRFN2 | leucine rich repeat and fibronectin type III domain containing 2 | 0.0189536 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0189324 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0188933 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0187683 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0186766 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0186232 |
| ZFHX3 | zinc finger homeobox 3 | 0.018467 |
| PHF14 | PHD finger protein 14 | 0.0184497 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0183814 |
| ZBTB7C | zinc finger and BTB domain containing 7C | 0.0181503 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.018136 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0178603 |
| FLNA | filamin A, alpha | 0.0176615 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0175025 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | -0.147336 |
| PTMA | prothymosin, alpha | -0.112433 |
| CENPF | centromere protein F, 350/400kDa | -0.108479 |
| TENM1 | teneurin transmembrane protein 1 | -0.0911679 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0897784 |
| ZNF292 | zinc finger protein 292 | -0.066912 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.06632 |
| XPO1 | exportin 1 | -0.0590843 |
| CALCA | calcitonin-related polypeptide alpha | -0.0553456 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0545683 |
| MATR3 | matrin 3 | -0.0518735 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0498591 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0483316 |
| RPL37A | ribosomal protein L37a | -0.0481864 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0481689 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0470521 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0463401 |
| RPL26 | ribosomal protein L26 | -0.0462762 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0456583 |
| RPS2 | ribosomal protein S2 | -0.0448845 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.043647 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0426422 |
| RPS21 | ribosomal protein S21 | -0.0416382 |
| RPS12 | ribosomal protein S12 | -0.0411866 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0409714 |
| PARD3 | par-3 family cell polarity regulator | -0.0401381 |
| PNN | pinin, desmosome associated protein | -0.0400041 |
| MKI67 | marker of proliferation Ki-67 | -0.039588 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0392125 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.037681 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0376386 |
| GPHN | gephyrin | -0.0371245 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0368448 |
| SET | SET nuclear proto-oncogene | -0.0367062 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0366313 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | -0.0363353 |
| KANTR | KDM5C adjacent non-coding transcript | -0.0358472 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.035293 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0347941 |
| RPL11 | ribosomal protein L11 | -0.0345452 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0344835 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0343413 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0338334 |
| PEG10 | paternally expressed 10 | -0.0332517 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0331615 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0330523 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0329199 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.032708 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0326201 |
| ECT2 | epithelial cell transforming 2 | -0.0325828 |
| PCM1 | pericentriolar material 1 | -0.0325726 |
| MED13L | mediator complex subunit 13-like | -0.0325629 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0325352 |
| TPX2 | TPX2, microtubule-associated | -0.0324421 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.032365 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0319709 |
| ANKRD28 | ankyrin repeat domain 28 | -0.031763 |
| NUF2 | NUF2, NDC80 kinetochore complex component | -0.0317028 |
| NKTR | natural killer cell triggering receptor | -0.0316339 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0310841 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | -0.0309657 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0306958 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0302566 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0301607 |
| RPS3 | ribosomal protein S3 | -0.0290399 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0289695 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0289014 |
| FOXN3 | forkhead box N3 | -0.0286621 |
| ARGLU1 | arginine and glutamate rich 1 | -0.0286251 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0283989 |
| RPS6 | ribosomal protein S6 | -0.0280316 |
| MT2A | metallothionein 2A | -0.0278602 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0277259 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0274393 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0272821 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0272374 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0271865 |
| ZFR | zinc finger RNA binding protein | -0.0270671 |
| SMC3 | structural maintenance of chromosomes 3 | -0.027043 |
| COX6C | cytochrome c oxidase subunit VIc | -0.0270314 |
| RPS8 | ribosomal protein S8 | -0.0269738 |
| CADM1 | cell adhesion molecule 1 | -0.0269489 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0268852 |
| ANLN | anillin, actin binding protein | -0.0267148 |
| RPS19 | ribosomal protein S19 | -0.0263589 |
| RBM25 | RNA binding motif protein 25 | -0.0263315 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0263158 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0262577 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) | -0.0262455 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0262002 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.0261947 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0260343 |
| PGK1 | phosphoglycerate kinase 1 | -0.0258807 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0258449 |
| SEPTIN7 | septin 7 | -0.0257823 |
| PHIP | pleckstrin homology domain interacting protein | -0.025631 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0254877 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0252922 |
| CCDC88A | coiled-coil domain containing 88A | -0.0252803 |
| NOP58 | NOP58 ribonucleoprotein | -0.0252661 |
