| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | 0.0673945 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0600652 |
| HMGA2 | high mobility group AT-hook 2 | 0.0562273 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0556934 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0541949 |
| DST | dystonin | 0.0529588 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0487515 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0480015 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.042571 |
| ACTG1 | actin gamma 1 | 0.0411191 |
| JAK1 | Janus kinase 1 | 0.0405368 |
| PRR16 | proline rich 16 | 0.040469 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0396215 |
| RUNX1 | runt-related transcription factor 1 | 0.0393348 |
| POTEF | POTE ankyrin domain family, member F | 0.0378178 |
| UTRN | utrophin | 0.036704 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0352779 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0336797 |
| RNF213 | ring finger protein 213 | 0.0333516 |
| ITGB4 | integrin, beta 4 | 0.0326575 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0312268 |
| LOC112694756 | uncharaterized LOC112694756 | 0.030631 |
| KLHL29 | kelch-like family member 29 | 0.0305726 |
| PRKCA | protein kinase C, alpha | 0.0302135 |
| TLE4 | transducin-like enhancer of split 4 | 0.0300611 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0299657 |
| ACTN1 | actinin, alpha 1 | 0.029601 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0296007 |
| SQSTM1 | sequestosome 1 | 0.029114 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0285751 |
| SMAD3 | SMAD family member 3 | 0.0282066 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0282022 |
| DOCK9 | dedicator of cytokinesis 9 | 0.0279724 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0271757 |
| FLNA | filamin A, alpha | 0.0268877 |
| EGFR | epidermal growth factor receptor | 0.0267155 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0264977 |
| FARS2 | phenylalanyl-tRNA synthetase 2, mitochondrial | 0.0264378 |
| HDAC9 | histone deacetylase 9 | 0.026378 |
| NAV2 | neuron navigator 2 | 0.0257895 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.02521 |
| RNF130 | ring finger protein 130 | 0.0247692 |
| ALS2 | amyotrophic lateral sclerosis 2 (juvenile) | 0.0247412 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0245195 |
| SKI | SKI proto-oncogene | 0.0245103 |
| SKIL | SKI-like proto-oncogene | 0.0244192 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0241132 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0240859 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0240779 |
| WWOX | WW domain containing oxidoreductase | 0.0239149 |
| SHPRH | SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase | 0.0234654 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0232505 |
| ANGPTL4 | angiopoietin-like 4 | 0.0231511 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0231139 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0226539 |
| RNF217 | ring finger protein 217 | 0.0225132 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0225064 |
| HPCAL1 | hippocalcin-like 1 | 0.0222923 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0222561 |
| LAMA5 | laminin, alpha 5 | 0.0221852 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0219617 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.021952 |
| TRAM2 | translocation associated membrane protein 2 | 0.021837 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0217287 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0214721 |
| CCDC88A | coiled-coil domain containing 88A | 0.0214108 |
| MED13L | mediator complex subunit 13-like | 0.0213476 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0209839 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0208724 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0207611 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0206424 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0200868 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0199843 |
| EZR | ezrin | 0.0198826 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0198183 |
| JUN | jun proto-oncogene | 0.0197238 |
| PLEC | plectin | 0.0196386 |
| IRF1 | interferon regulatory factor 1 | 0.0194082 |
| C2CD3 | C2 calcium-dependent domain containing 3 | 0.019404 |
| AREG | amphiregulin | 0.0193596 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0193119 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0190211 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0189731 |
| ATG10 | autophagy related 10 | 0.0183611 |
| VEGFA | vascular endothelial growth factor A | 0.0183255 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0182806 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.018273 |
| WDR27 | WD repeat domain 27 | 0.0182395 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0182309 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0182103 |
| TPI1 | triosephosphate isomerase 1 | 0.0181852 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0181061 |
| PCED1B | PC-esterase domain containing 1B | 0.0180971 |
| EXOC4 | exocyst complex component 4 | 0.0178983 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.017877 |
| MYOF | myoferlin | 0.0177776 |
| TRIP11 | thyroid hormone receptor interactor 11 | 0.0177452 |
| TAGLN2 | transgelin 2 | 0.0177132 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0176352 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0175729 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.351532 |
| RBM39 | RNA binding motif protein 39 | -0.125089 |
| VIM | vimentin | -0.0962299 |
| PTMA | prothymosin, alpha | -0.0768811 |
| DSCAM | Down syndrome cell adhesion molecule | -0.073706 |
| TMSB10 | thymosin beta 10 | -0.0731955 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0727534 |
| LDHA | lactate dehydrogenase A | -0.066425 |
| SMYD3 | SET and MYND domain containing 3 | -0.0612568 |
| GOLGA4 | golgin A4 | -0.0596372 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0591002 |
| DEK | DEK proto-oncogene | -0.0564472 |
| SETD5 | SET domain containing 5 | -0.0555828 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0548305 |
| CANX | calnexin | -0.0540941 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0531999 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0521445 |
| TXNRD1 | thioredoxin reductase 1 | -0.0519112 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0515925 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0502216 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0492911 |
| ECT2 | epithelial cell transforming 2 | -0.0474217 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0459209 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0454078 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0428098 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0424932 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0418877 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0412969 |
| TMEM123 | transmembrane protein 123 | -0.0408707 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0406267 |
| DNER | delta/notch-like EGF repeat containing | -0.0404723 |
| ZNF292 | zinc finger protein 292 | -0.0402025 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0401887 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0401357 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0398213 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0397361 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0392919 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0392827 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0388597 |
| RDX | radixin | -0.0388406 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0386586 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0384491 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0384352 |
| RPL4 | ribosomal protein L4 | -0.0382637 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0380655 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0378297 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0377163 |
| TPM4 | tropomyosin 4 | -0.0372934 |
| OSMR | oncostatin M receptor | -0.0371559 |
| PHF20 | PHD finger protein 20 | -0.0371328 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0368249 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0365805 |
| RPL35A | ribosomal protein L35a | -0.0365598 |
| CUL3 | cullin 3 | -0.0364053 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0362046 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0361071 |
| NUP58 | nucleoporin 58 | -0.0359829 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.035743 |
| MATR3 | matrin 3 | -0.0357173 |
| NKTR | natural killer cell triggering receptor | -0.035448 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0350041 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0348462 |
| RPL23 | ribosomal protein L23 | -0.0347265 |
| JMJD1C | jumonji domain containing 1C | -0.03442 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0340028 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0339868 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0339056 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0335589 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0335363 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0334932 |
| RPL12 | ribosomal protein L12 | -0.0333852 |
| ANLN | anillin, actin binding protein | -0.0332944 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0331547 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0331041 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | -0.0326534 |
| PARD3 | par-3 family cell polarity regulator | -0.0326377 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0323199 |
| PAPOLA | poly(A) polymerase alpha | -0.0321055 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.031507 |
| IER3 | immediate early response 3 | -0.0315041 |
| KIF5B | kinesin family member 5B | -0.0313483 |
| CEP95 | centrosomal protein 95kDa | -0.0312912 |
| FAF2 | Fas associated factor family member 2 | -0.0311626 |
| TCERG1 | transcription elongation regulator 1 | -0.0309008 |
| FUS | FUS RNA binding protein | -0.0307453 |
| AK1 | adenylate kinase 1 | -0.0304751 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0304737 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0302874 |
| CLTC | clathrin, heavy chain (Hc) | -0.0302788 |
| PGK1 | phosphoglycerate kinase 1 | -0.029912 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0298295 |
| SPAG9 | sperm associated antigen 9 | -0.0298081 |
| CENPF | centromere protein F, 350/400kDa | -0.0297944 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.02974 |
| KIAA1328 | KIAA1328 | -0.0297314 |
| CEP295 | centrosomal protein 295kDa | -0.0293385 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0293279 |
| RPL30 | ribosomal protein L30 | -0.0292903 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0289405 |
| SDC4 | syndecan 4 | -0.0289145 |
