| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.0848367 |
| RCOR1 | REST corepressor 1 | 0.0668865 |
| LAMB3 | laminin, beta 3 | 0.0616614 |
| LAMA4 | laminin, alpha 4 | 0.0525821 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0455316 |
| FHL2 | four and a half LIM domains 2 | 0.0444585 |
| RPS3 | ribosomal protein S3 | 0.0431143 |
| EGR1 | early growth response 1 | 0.0428992 |
| FAT1 | FAT atypical cadherin 1 | 0.042288 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0410597 |
| SEPTIN9 | septin 9 | 0.0401679 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0396829 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0372546 |
| EPHA2 | EPH receptor A2 | 0.0364758 |
| VCL | vinculin | 0.0336528 |
| NDRG1 | N-myc downstream regulated 1 | 0.0329023 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0328328 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0313775 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0312387 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0302336 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0283352 |
| DUSP4 | dual specificity phosphatase 4 | 0.0281407 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0275219 |
| RANBP9 | RAN binding protein 9 | 0.0273077 |
| TJP1 | tight junction protein 1 | 0.0271621 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0266133 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0263721 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0255631 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0244438 |
| SMAD3 | SMAD family member 3 | 0.0244198 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0242657 |
| RACK1 | receptor for activated C kinase 1 | 0.0235156 |
| SNX9 | sorting nexin 9 | 0.0232258 |
| CPOX | coproporphyrinogen oxidase | 0.0231905 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0227361 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0226758 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0219142 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.021891 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.021707 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0215081 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0214607 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.021258 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0212282 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.021157 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0206911 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0206731 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.020409 |
| YBX1 | Y box binding protein 1 | 0.0203161 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0202419 |
| SGMS2 | sphingomyelin synthase 2 | 0.0201303 |
| FLNA | filamin A, alpha | 0.019869 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0197407 |
| DIAPH1 | diaphanous-related formin 1 | 0.0195829 |
| LMO7 | LIM domain 7 | 0.0194405 |
| ATXN1 | ataxin 1 | 0.0192239 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 0.0190881 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0189678 |
| EVA1C | eva-1 homolog C (C. elegans) | 0.0189609 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0187862 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0183826 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 | 0.018284 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0182318 |
| YAP1 | Yes-associated protein 1 | 0.0180972 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.0177694 |
| RPL11 | ribosomal protein L11 | 0.0177086 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0175578 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0175504 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0175108 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0170074 |
| ANXA11 | annexin A11 | 0.016967 |
| RPS12 | ribosomal protein S12 | 0.0168744 |
| ATL2 | atlastin GTPase 2 | 0.0167183 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0167104 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0166472 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0162825 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0162592 |
| NUP58 | nucleoporin 58 | 0.0162198 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0160542 |
| CD9 | CD9 molecule | 0.0160348 |
| XPO6 | exportin 6 | 0.015772 |
| CLTC | clathrin, heavy chain (Hc) | 0.0157219 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0155459 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0155154 |
| UBAP2 | ubiquitin associated protein 2 | 0.0155073 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0154505 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0153975 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0153841 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0153701 |
| USP6NL | USP6 N-terminal like | 0.0153476 |
| TES | testin LIM domain protein | 0.0152713 |
| CLDND1 | claudin domain containing 1 | 0.0151091 |
| BRD2 | bromodomain containing 2 | 0.0150353 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | 0.0148748 |
| AFDN | afadin, adherens junction formation factor | 0.0147654 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.014761 |
| ZNF654 | zinc finger protein 654 | 0.0147576 |
| UTRN | utrophin | 0.0146889 |
| RNF43 | ring finger protein 43 | 0.0146873 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0146841 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0145885 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.158809 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.150554 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.139794 |
| HMGA2 | high mobility group AT-hook 2 | -0.124372 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.113965 |
| FHIT | fragile histidine triad | -0.110917 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0991086 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0896211 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0889024 |
| EZR | ezrin | -0.0753514 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0744411 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.073604 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0735419 |
| RAD51B | RAD51 paralog B | -0.0734066 |
| HDAC2 | histone deacetylase 2 | -0.0714703 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0710934 |
| IER3 | immediate early response 3 | -0.0695674 |
| ANXA1 | annexin A1 | -0.066243 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0633265 |
| RPS6 | ribosomal protein S6 | -0.0620787 |
| CUX1 | cut-like homeobox 1 | -0.0537532 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0525993 |
| AOPEP | aminopeptidase O (putative) | -0.0498066 |
| FERMT1 | fermitin family member 1 | -0.0481866 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0480695 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0471042 |
| AHNAK | AHNAK nucleoprotein | -0.0452529 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0435122 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.041661 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0406472 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0398399 |
| RPS24 | ribosomal protein S24 | -0.0396772 |
| SERINC5 | serine incorporator 5 | -0.0375127 |
| DIAPH2 | diaphanous-related formin 2 | -0.0374049 |
| MTAP | methylthioadenosine phosphorylase | -0.0368263 |
| CANX | calnexin | -0.0366887 |
| EXOC4 | exocyst complex component 4 | -0.035229 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0345403 |
| TMSB10 | thymosin beta 10 | -0.0342255 |
| SQSTM1 | sequestosome 1 | -0.0335794 |
| GNAT3 | guanine nucleotide binding protein, alpha transducing 3 | -0.033575 |
| SMYD3 | SET and MYND domain containing 3 | -0.0324586 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0315528 |
| GPC5 | glypican 5 | -0.0311362 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0310472 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0306174 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0302191 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0301615 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0300143 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0297041 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0290059 |
| OXR1 | oxidation resistance 1 | -0.0286698 |
| GPHN | gephyrin | -0.0285848 |
| NEMF | nuclear export mediator factor | -0.0281821 |
| MKI67 | marker of proliferation Ki-67 | -0.028121 |
| CD2AP | CD2-associated protein | -0.027257 |
| TXNIP | thioredoxin interacting protein | -0.0272387 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0272327 |
| RPS25 | ribosomal protein S25 | -0.0268766 |
| APP | amyloid beta (A4) precursor protein | -0.0266168 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.0265778 |
| PDS5A | PDS5 cohesin associated factor A | -0.0259374 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0259337 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0254869 |
| SBF2 | SET binding factor 2 | -0.0253419 |
| S100A6 | S100 calcium binding protein A6 | -0.0240689 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0240312 |
| FUS | FUS RNA binding protein | -0.0239617 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | -0.0238859 |
| UBC | ubiquitin C | -0.0236269 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.023324 |
| ANXA2 | annexin A2 | -0.0232968 |
| PARD3 | par-3 family cell polarity regulator | -0.0232768 |
| RREB1 | ras responsive element binding protein 1 | -0.023255 |
| NFIA | nuclear factor I/A | -0.0232323 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.022913 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0228481 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0226367 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0225965 |
| RASAL2 | RAS protein activator like 2 | -0.0225292 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0223267 |
| ZNF638 | zinc finger protein 638 | -0.0223105 |
| ITGB4 | integrin, beta 4 | -0.0221667 |
| RPLP1 | ribosomal protein, large, P1 | -0.0221544 |
| GPATCH8 | G patch domain containing 8 | -0.0220862 |
| TENM3 | teneurin transmembrane protein 3 | -0.0220262 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0217249 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0217111 |
| ZNF292 | zinc finger protein 292 | -0.021691 |
| KITLG | KIT ligand | -0.0216303 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0215739 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.0214862 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0214626 |
| RPL4 | ribosomal protein L4 | -0.0214588 |
| LAMB1 | laminin, beta 1 | -0.0212046 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.021103 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0209126 |
| KRT8 | keratin 8, type II | -0.0209005 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0208803 |
| EHBP1 | EH domain binding protein 1 | -0.020852 |
