| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.344954 |
| ACTG1 | actin gamma 1 | 0.101818 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0695359 |
| CDK6 | cyclin-dependent kinase 6 | 0.068096 |
| SPATA13 | spermatogenesis associated 13 | 0.0644934 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0605576 |
| KRT18 | keratin 18, type I | 0.0566965 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.055905 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0554576 |
| PROX1 | prospero homeobox 1 | 0.0514419 |
| DST | dystonin | 0.0496016 |
| SYT1 | synaptotagmin I | 0.0480639 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.047954 |
| DSPP | dentin sialophosphoprotein | 0.0464507 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0462325 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0444338 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0436539 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0435539 |
| TMEM123 | transmembrane protein 123 | 0.0418252 |
| ITGA6 | integrin, alpha 6 | 0.0378198 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0370418 |
| TNS3 | tensin 3 | 0.0358273 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.034685 |
| PERP | PERP, TP53 apoptosis effector | 0.0329269 |
| BPTF | bromodomain PHD finger transcription factor | 0.0327404 |
| NOTUM | notum pectinacetylesterase homolog (Drosophila) | 0.0319962 |
| KPNB1 | karyopherin (importin) beta 1 | 0.031377 |
| MKI67 | marker of proliferation Ki-67 | 0.0307163 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0304216 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0293928 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0286737 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0286634 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0285292 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0284398 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0279045 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0278973 |
| OXR1 | oxidation resistance 1 | 0.0277998 |
| PCM1 | pericentriolar material 1 | 0.0277828 |
| POTEF | POTE ankyrin domain family, member F | 0.0277553 |
| BCL2L1 | BCL2-like 1 | 0.0275254 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0273204 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0272402 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0271369 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0270714 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 0.0266035 |
| THOC2 | THO complex 2 | 0.0261004 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | 0.0246308 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0245792 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.024491 |
| SNX9 | sorting nexin 9 | 0.0244319 |
| RPL7L1 | ribosomal protein L7-like 1 | 0.0239342 |
| RBM26 | RNA binding motif protein 26 | 0.023513 |
| LMO7 | LIM domain 7 | 0.0230632 |
| SH3D19 | SH3 domain containing 19 | 0.0230269 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0228906 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0226336 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0224322 |
| TPM4 | tropomyosin 4 | 0.0220751 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0220615 |
| CENPF | centromere protein F, 350/400kDa | 0.0219959 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0214658 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0214566 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0213871 |
| MCC | mutated in colorectal cancers | 0.0211089 |
| ENO1 | enolase 1, (alpha) | 0.0210267 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0209117 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0208351 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0207625 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0207606 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0207522 |
| INTS13 | integrator complex subunit 13 | 0.0201839 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0201213 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0198901 |
| AXIN2 | axin 2 | 0.0197259 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0194766 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0194691 |
| TOX3 | TOX high mobility group box family member 3 | 0.0192881 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.019256 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.019152 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0191485 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0191283 |
| KIZ | kizuna centrosomal protein | 0.0190835 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0190182 |
| WDR43 | WD repeat domain 43 | 0.018936 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.0188094 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0186426 |
| ETNK1 | ethanolamine kinase 1 | 0.0185706 |
| DEK | DEK proto-oncogene | 0.0185156 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0183345 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0183219 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0181316 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0181258 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0180988 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.017973 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0179517 |
| CDC16 | cell division cycle 16 | 0.0177868 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0177439 |
| COBL | cordon-bleu WH2 repeat protein | 0.0177336 |
| YAP1 | Yes-associated protein 1 | 0.0175629 |
| CDCP1 | CUB domain containing protein 1 | 0.0175478 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAV2 | neuron navigator 2 | -0.111997 |
| TMSB10 | thymosin beta 10 | -0.0984566 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0937789 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0921509 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0887441 |
| INTS6 | integrator complex subunit 6 | -0.0884923 |
| RPL23 | ribosomal protein L23 | -0.0780075 |
| RPL35A | ribosomal protein L35a | -0.0751878 |
| PTMA | prothymosin, alpha | -0.074797 |
| ASPH | aspartate beta-hydroxylase | -0.055066 |
| RPS19 | ribosomal protein S19 | -0.0542005 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0541108 |
| RPS6 | ribosomal protein S6 | -0.0511679 |
| ANLN | anillin, actin binding protein | -0.048756 |
| RPL26 | ribosomal protein L26 | -0.0441129 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0434155 |
| FHIT | fragile histidine triad | -0.0429845 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0429665 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0427996 |
| RPL31 | ribosomal protein L31 | -0.0421714 |
| AHNAK | AHNAK nucleoprotein | -0.0417849 |
| DIAPH3 | diaphanous-related formin 3 | -0.0411343 |
| RPS21 | ribosomal protein S21 | -0.0397082 |
| RPL37A | ribosomal protein L37a | -0.0379562 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0374685 |
| RPS12 | ribosomal protein S12 | -0.0372974 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0369272 |
| MT2A | metallothionein 2A | -0.0365276 |
| FUS | FUS RNA binding protein | -0.0364878 |
| RBM39 | RNA binding motif protein 39 | -0.0363423 |
| KRT8 | keratin 8, type II | -0.0354996 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0350567 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0348585 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0344668 |
| RPLP1 | ribosomal protein, large, P1 | -0.034462 |
| RPLP2 | ribosomal protein, large, P2 | -0.0340312 |
| FLNB | filamin B, beta | -0.0339718 |
| RPL28 | ribosomal protein L28 | -0.0338512 |
| MYO1D | myosin ID | -0.0333908 |
| RPS24 | ribosomal protein S24 | -0.0333703 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0326059 |
| EMP1 | epithelial membrane protein 1 | -0.0323059 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0322209 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0320889 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0305086 |
| RPL35 | ribosomal protein L35 | -0.0303198 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0299526 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0299346 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0295123 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0294572 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0284688 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0283133 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0275376 |
| RPL19 | ribosomal protein L19 | -0.0272868 |
| PKM | pyruvate kinase, muscle | -0.0270716 |
| RPS17 | ribosomal protein S17 | -0.0267115 |
| CADM1 | cell adhesion molecule 1 | -0.02641 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0261042 |
| RPS27A | ribosomal protein S27a | -0.0258386 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0256213 |
| ZNF292 | zinc finger protein 292 | -0.025472 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0253895 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0251981 |
| NABP1 | nucleic acid binding protein 1 | -0.0250988 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0249036 |
| SRPK2 | SRSF protein kinase 2 | -0.0248962 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0247085 |
| RCC1 | regulator of chromosome condensation 1 | -0.024505 |
| SQSTM1 | sequestosome 1 | -0.0245028 |
| EFNB2 | ephrin-B2 | -0.0244746 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0244031 |
| MSI2 | musashi RNA-binding protein 2 | -0.0239283 |
| RAD51B | RAD51 paralog B | -0.0237594 |
| RPS14 | ribosomal protein S14 | -0.0237044 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0235653 |
| RPS5 | ribosomal protein S5 | -0.0235293 |
| ACTN4 | actinin, alpha 4 | -0.0235125 |
| KLF12 | Kruppel-like factor 12 | -0.0232814 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0231314 |
| RPL38 | ribosomal protein L38 | -0.0229861 |
| USP34 | ubiquitin specific peptidase 34 | -0.0226899 |
| RPS2 | ribosomal protein S2 | -0.0226159 |
| ARF4 | ADP-ribosylation factor 4 | -0.0221062 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0220906 |
| RPL34 | ribosomal protein L34 | -0.0216852 |
| FNDC3B | fibronectin type III domain containing 3B | -0.021671 |
| PRELID2 | PRELI domain containing 2 | -0.0212105 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0211302 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0210264 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0209371 |
| AEBP2 | AE binding protein 2 | -0.0209246 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0208264 |
| LRRC23 | leucine rich repeat containing 23 | -0.0208213 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0203478 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0202536 |
| HDAC4 | histone deacetylase 4 | -0.020181 |
| RBM6 | RNA binding motif protein 6 | -0.0200751 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0200346 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0198668 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0198289 |
