| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGA2 | high mobility group AT-hook 2 | 0.0355212 |
| VEGFA | vascular endothelial growth factor A | 0.0286483 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0280895 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.02762 |
| HLA-C | major histocompatibility complex, class I, C | 0.025234 |
| EGFR | epidermal growth factor receptor | 0.0200707 |
| MCL1 | myeloid cell leukemia 1 | 0.0183429 |
| FN1 | fibronectin 1 | 0.0177321 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0172734 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0172423 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0165749 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0150566 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0147975 |
| FMNL2 | formin-like 2 | 0.0147484 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0145912 |
| IL33 | interleukin 33 | 0.0145022 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0142899 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0136211 |
| PLEC | plectin | 0.0132316 |
| SMTN | smoothelin | 0.0131207 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0127524 |
| HDAC9 | histone deacetylase 9 | 0.0126167 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0125779 |
| SMOX | spermine oxidase | 0.0123561 |
| ITGA1 | integrin, alpha 1 | 0.0123476 |
| ZNF638 | zinc finger protein 638 | 0.0119898 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0117853 |
| FNDC3A | fibronectin type III domain containing 3A | 0.011477 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0113243 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0112736 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0112246 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0110882 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0109151 |
| ITSN2 | intersectin 2 | 0.0108442 |
| IGF2 | insulin-like growth factor 2 | 0.0107878 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0107628 |
| SEPTIN9 | septin 9 | 0.0107071 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0105632 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0105483 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0103209 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0102066 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.00935938 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.00924196 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.00915047 |
| STC1 | stanniocalcin 1 | 0.00908315 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.00901216 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00894793 |
| MYO9A | myosin IXA | 0.00892923 |
| SNX9 | sorting nexin 9 | 0.00876684 |
| PLPP3 | phospholipid phosphatase 3 | 0.00866092 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.00865073 |
| HLA-E | major histocompatibility complex, class I, E | 0.00856322 |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.00851055 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.00845674 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.00844205 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.00842661 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | 0.00820412 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.00815294 |
| COL5A3 | collagen, type V, alpha 3 | 0.00810809 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.00792653 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.00791027 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.00779451 |
| SON | SON DNA binding protein | 0.00773333 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.00772192 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.00747572 |
| FAM219A | family with sequence similarity 219, member A | 0.00745015 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.00744296 |
| CUL4A | cullin 4A | 0.00737281 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00734227 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0072937 |
| KIAA1217 | KIAA1217 | 0.00727464 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.00725295 |
| YEATS2 | YEATS domain containing 2 | 0.00719804 |
| PER2 | period circadian clock 2 | 0.00714638 |
| CDR2L | cerebellar degeneration-related protein 2-like | 0.00712485 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | 0.00711836 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.00704085 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 | 0.00702282 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.00700474 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.00699664 |
| CEP250 | centrosomal protein 250kDa | 0.00695349 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.00674199 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.00670422 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.00670183 |
| TLE5 | TLE family member 5, transcriptional modulator | 0.00666757 |
| RNF150 | ring finger protein 150 | 0.00664344 |
| ERCC1 | excision repair cross-complementation group 1 | 0.00659053 |
| UBTD2 | ubiquitin domain containing 2 | 0.00658799 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.00658577 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.00648281 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.00637389 |
| PLXNA3 | plexin A3 | 0.00636505 |
| PGM3 | phosphoglucomutase 3 | 0.00635154 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.00632878 |
| DAB2IP | DAB2 interacting protein | 0.00631808 |
| CCDC146 | coiled-coil domain containing 146 | 0.00630559 |
| RSRP1 | arginine/serine-rich protein 1 | 0.00627376 |
| DOCK1 | dedicator of cytokinesis 1 | 0.00618003 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.00615711 |
| MGLL | monoglyceride lipase | 0.00614807 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.283296 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.271062 |
| COL1A1 | collagen, type I, alpha 1 | -0.17411 |
| INHBA | inhibin, beta A | -0.169171 |
| MMP1 | matrix metallopeptidase 1 | -0.162185 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.150104 |
| COL6A3 | collagen, type VI, alpha 3 | -0.123192 |
| TMSB10 | thymosin beta 10 | -0.11447 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.113701 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.108775 |
| COL1A2 | collagen, type I, alpha 2 | -0.102207 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0905277 |
| PTMA | prothymosin, alpha | -0.0762543 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0712757 |
| FTL | ferritin, light polypeptide | -0.0677731 |
| EMP1 | epithelial membrane protein 1 | -0.0653008 |
| AHNAK | AHNAK nucleoprotein | -0.0632901 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0631934 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0624958 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0537577 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0522143 |
| HLA-B | major histocompatibility complex, class I, B | -0.0468692 |
| CALU | calumenin | -0.0452714 |
| CALR | calreticulin | -0.0445173 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0436879 |
| CALD1 | caldesmon 1 | -0.0430801 |
| CANX | calnexin | -0.0410813 |
| RPL23 | ribosomal protein L23 | -0.0398035 |
| MAP1B | microtubule-associated protein 1B | -0.0395804 |
| PKM | pyruvate kinase, muscle | -0.0386949 |
| B2M | beta-2-microglobulin | -0.0385156 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0384837 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0384817 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0381803 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0380687 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0365536 |
| SEPTIN11 | septin 11 | -0.0362401 |
| LDHA | lactate dehydrogenase A | -0.0359393 |
| S100A6 | S100 calcium binding protein A6 | -0.0358269 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0356288 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0355011 |
| PGK1 | phosphoglycerate kinase 1 | -0.0354361 |
| RPS6 | ribosomal protein S6 | -0.0353153 |
| POTEF | POTE ankyrin domain family, member F | -0.0351658 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0351268 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0350751 |
| TPM4 | tropomyosin 4 | -0.0339137 |
| RPS24 | ribosomal protein S24 | -0.0337345 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0335036 |
| DST | dystonin | -0.0329304 |
| FBN1 | fibrillin 1 | -0.0327296 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0326994 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0326591 |
| RPLP1 | ribosomal protein, large, P1 | -0.0320943 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0311903 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.030378 |
| RPL34 | ribosomal protein L34 | -0.0300907 |
| RPS8 | ribosomal protein S8 | -0.030005 |
| RPS19 | ribosomal protein S19 | -0.0298675 |
| ANXA2 | annexin A2 | -0.0297711 |
| IER3 | immediate early response 3 | -0.0294376 |
| CDH13 | cadherin 13 | -0.0290141 |
| H1-0 | H1.0 linker histone | -0.0288281 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0287194 |
| RPL35A | ribosomal protein L35a | -0.0284498 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0284387 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0283795 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0282138 |
| PRSS23 | protease, serine, 23 | -0.0280236 |
| MED13L | mediator complex subunit 13-like | -0.0274818 |
| ENO1 | enolase 1, (alpha) | -0.0273951 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0269902 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0269763 |
| RPL12 | ribosomal protein L12 | -0.0266519 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0266439 |
| COL3A1 | collagen, type III, alpha 1 | -0.0261971 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.026143 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0259322 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0257827 |
| TPI1 | triosephosphate isomerase 1 | -0.0256221 |
| UBC | ubiquitin C | -0.02545 |
| ANKRD28 | ankyrin repeat domain 28 | -0.025298 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0252951 |
| RAI14 | retinoic acid induced 14 | -0.0250806 |
| GOLGA4 | golgin A4 | -0.0248225 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0247524 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.024468 |
| USP3 | ubiquitin specific peptidase 3 | -0.024465 |
| RRBP1 | ribosome binding protein 1 | -0.0241116 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0237348 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0235676 |
| HLA-A | major histocompatibility complex, class I, A | -0.023513 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0234875 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0234385 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0234258 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.023373 |
| RPL32 | ribosomal protein L32 | -0.0229918 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0229222 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0226952 |
| COL4A1 | collagen, type IV, alpha 1 | -0.0226772 |
