| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/77993 |
| Similar Terms | |
| Downloads & Tools |
199 proteins with high or low expression in Eletriptan relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PIP | prolactin-induced protein | 1.05 |
| UBE2Q2 | ubiquitin-conjugating enzyme E2Q family member 2 | 0.87 |
| CCDC15 | coiled-coil domain containing 15 | 0.84 |
| KIAA0586 | KIAA0586 | 0.8 |
| TMEM64 | transmembrane protein 64 | 0.63 |
| COL6A3 | collagen, type VI, alpha 3 | 0.61 |
| MBP | myelin basic protein | 0.55 |
| TIPE1 | TNF alpha induced protein 8 like 1 | 0.52 |
| CD63 | CD63 molecule | 0.51 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.47 |
| COX19 | COX19 cytochrome c oxidase assembly factor | 0.47 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.43 |
| APLF | aprataxin and PNKP like factor | 0.43 |
| ZNF431 | zinc finger protein 431 | 0.41 |
| DCAF17 | DDB1 and CUL4 associated factor 17 | 0.41 |
| TRAK2 | trafficking protein, kinesin binding 2 | 0.41 |
| REST | RE1-silencing transcription factor | 0.4 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.4 |
| AKT1S1 | AKT1 substrate 1 (proline-rich) | 0.4 |
| KLK10 | kallikrein-related peptidase 10 | 0.39 |
| DALRD3 | DALR anticodon binding domain containing 3 | 0.39 |
| NPHP1 | nephronophthisis 1 (juvenile) | 0.39 |
| SERF2 | small EDRK-rich factor 2 | 0.39 |
| SESN1 | sestrin 1 | 0.39 |
| ZNF749 | zinc finger protein 749 | 0.39 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 0.36 |
| RAB24 | RAB24, member RAS oncogene family | 0.35 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | 0.35 |
| RNF220 | ring finger protein 220 | 0.34 |
| IFFO2 | intermediate filament family orphan 2 | 0.34 |
| ARHGAP44 | Rho GTPase activating protein 44 | 0.34 |
| ERCC6 | excision repair cross-complementation group 6 | 0.33 |
| ZNF551 | zinc finger protein 551 | 0.33 |
| FITM2 | fat storage-inducing transmembrane protein 2 | 0.33 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 | 0.33 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.32 |
| NDFIP2 | Nedd4 family interacting protein 2 | 0.31 |
| MICB | MHC class I polypeptide-related sequence B | 0.31 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | 0.31 |
| PCSK9 | proprotein convertase subtilisin/kexin type 9 | 0.31 |
| TMPPE | transmembrane protein with metallophosphoesterase domain | 0.3 |
| CLASP2 | cytoplasmic linker associated protein 2 | 0.3 |
| F2R | coagulation factor II (thrombin) receptor | 0.29 |
| GCH1 | GTP cyclohydrolase 1 | 0.29 |
| MCOLN1 | mucolipin 1 | 0.28 |
| ZNF184 | zinc finger protein 184 | 0.28 |
| ABHD13 | abhydrolase domain containing 13 | 0.28 |
| MPZL2 | myelin protein zero-like 2 | 0.28 |
| ZFP64 | ZFP64 zinc finger protein | 0.27 |
| TMEM205 | transmembrane protein 205 | 0.27 |
| ZNF791 | zinc finger protein 791 | 0.27 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | 0.27 |
| GOLGA4 | golgin A4 | 0.27 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 | 0.27 |
| PRXL2C | peroxiredoxin like 2C | 0.26 |
| HAUS1 | HAUS augmin-like complex, subunit 1 | 0.26 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.26 |
| DOCK11 | dedicator of cytokinesis 11 | 0.26 |
| ZBTB3 | zinc finger and BTB domain containing 3 | 0.26 |
| CCNE2 | cyclin E2 | 0.26 |
| NOTCH3 | notch 3 | 0.26 |
| DUSP5 | dual specificity phosphatase 5 | 0.25 |
| GPATCH4 | G patch domain containing 4 | 0.25 |
| LAGE3 | L antigen family, member 3 | 0.25 |
| FTL | ferritin, light polypeptide | 0.25 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.25 |
| RNF126 | ring finger protein 126 | 0.24 |
| HHEX | hematopoietically expressed homeobox | 0.24 |
| MSLN | mesothelin | 0.24 |
| ZNF286B | zinc finger protein 286B | 0.24 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 | 0.24 |
| DNAH1 | dynein, axonemal, heavy chain 1 | 0.24 |
| GK5 | glycerol kinase 5 (putative) | 0.23 |
| SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 | 0.23 |
| PDP2 | pyruvate dehyrogenase phosphatase catalytic subunit 2 | 0.23 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.23 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.23 |
| ANAPC11 | anaphase promoting complex subunit 11 | 0.23 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) | 0.23 |
| APOB | apolipoprotein B | 0.23 |
| C5ORF24 | chromosome 5 open reading frame 24 | 0.23 |
| CFAP58 | cilia and flagella associated protein 58 | 0.23 |
| DMD | dystrophin | 0.23 |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B | 0.23 |
| C19ORF25 | chromosome 19 open reading frame 25 | 0.22 |
| FZD7 | frizzled class receptor 7 | 0.22 |
| SPOPL | speckle-type POZ protein-like | 0.22 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.22 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.22 |
| CLN3 | ceroid-lipofuscinosis, neuronal 3 | 0.22 |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa | 0.22 |
| BCL9 | B-cell CLL/lymphoma 9 | 0.22 |
| RFK | riboflavin kinase | 0.22 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.22 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 | 0.22 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.22 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 | 0.22 |
| FAM193A | family with sequence similarity 193, member A | 0.22 |
| ZNF430 | zinc finger protein 430 | 0.22 |
| RPL37 | ribosomal protein L37 | 0.22 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VAV1 | vav 1 guanine nucleotide exchange factor | -2.04 |
| PLEKHH2 | pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 | -1.97 |
| LMOD1 | leiomodin 1 (smooth muscle) | -1.41 |
| KALRN | kalirin, RhoGEF kinase | -1.14 |
| ZNF658 | zinc finger protein 658 | -0.88 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.84 |
| SKIL | SKI-like proto-oncogene | -0.84 |
| GPD1 | glycerol-3-phosphate dehydrogenase 1 (soluble) | -0.82 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 | -0.78 |
| ADCY10 | adenylate cyclase 10 (soluble) | -0.76 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.75 |
| FAM110A | family with sequence similarity 110, member A | -0.74 |
| KPTN | kaptin (actin binding protein) | -0.73 |
| SLC43A2 | solute carrier family 43 (amino acid system L transporter), member 2 | -0.63 |
| MAGEE1 | melanoma antigen family E1 | -0.61 |
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 | -0.53 |
| RNF13 | ring finger protein 13 | -0.51 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.51 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.49 |
| CAPN6 | calpain 6 | -0.48 |
| C1ORF109 | chromosome 1 open reading frame 109 | -0.48 |
| TSSC4 | tumor suppressing subtransferable candidate 4 | -0.47 |
| MIS12 | MIS12 kinetochore complex component | -0.46 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.46 |
| ZFP30 | ZFP30 zinc finger protein | -0.45 |
| ICAM1 | intercellular adhesion molecule 1 | -0.44 |
| PIAS3 | protein inhibitor of activated STAT, 3 | -0.44 |
| ATAT1 | alpha tubulin acetyltransferase 1 | -0.44 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.43 |
| CFAP410 | cilia and flagella associated protein 410 | -0.43 |
| TTC39B | tetratricopeptide repeat domain 39B | -0.43 |
| CCNQ | cyclin Q | -0.43 |
| ABHD4 | abhydrolase domain containing 4 | -0.42 |
| SEPHS2 | selenophosphate synthetase 2 | -0.42 |
| MAGEF1 | melanoma antigen family F1 | -0.42 |
| ABCC9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 | -0.42 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.41 |
| IER5L | immediate early response 5-like | -0.41 |
| TCP11L1 | t-complex 11, testis-specific-like 1 | -0.4 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.4 |
| FHOD3 | formin homology 2 domain containing 3 | -0.39 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit | -0.39 |
| TMC4 | transmembrane channel-like 4 | -0.38 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -0.38 |
| MOCS2 | molybdenum cofactor synthesis 2 | -0.38 |
| MPV17 | MpV17 mitochondrial inner membrane protein | -0.38 |
| GNG5 | guanine nucleotide binding protein (G protein), gamma 5 | -0.38 |
| NPHP3 | nephronophthisis 3 (adolescent) | -0.37 |
| PPT1 | palmitoyl-protein thioesterase 1 | -0.37 |
| KITLG | KIT ligand | -0.37 |
| ZBTB49 | zinc finger and BTB domain containing 49 | -0.36 |
| ZNF317 | zinc finger protein 317 | -0.36 |
| DMWD | dystrophia myotonica, WD repeat containing | -0.36 |
| DES | desmin | -0.35 |
| MEX3A | mex-3 RNA binding family member A | -0.35 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.35 |
| MRAS | muscle RAS oncogene homolog | -0.35 |
| CHCHD4 | coiled-coil-helix-coiled-coil-helix domain containing 4 | -0.34 |
| SYN2 | synapsin II | -0.34 |
| CCAR2 | cell cycle and apoptosis regulator 2 | -0.34 |
| DESI1 | desumoylating isopeptidase 1 | -0.33 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 | -0.33 |
| SIGMAR1 | sigma non-opioid intracellular receptor 1 | -0.33 |
| ING4 | inhibitor of growth family, member 4 | -0.33 |
| SLC22A18 | solute carrier family 22, member 18 | -0.32 |
| DIPK1B | divergent protein kinase domain 1B | -0.32 |
| ZNF611 | zinc finger protein 611 | -0.32 |
| CES2 | carboxylesterase 2 | -0.32 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.31 |
| CALD1 | caldesmon 1 | -0.31 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.31 |
| HGH1 | HGH1 homolog (S. cerevisiae) | -0.31 |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 | -0.31 |
| ZNF136 | zinc finger protein 136 | -0.31 |
| C18ORF32 | chromosome 18 open reading frame 32 | -0.31 |
| CD58 | CD58 molecule | -0.3 |
| ZNF92 | zinc finger protein 92 | -0.3 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.3 |
| CDC26 | cell division cycle 26 | -0.3 |
| NEIL1 | nei endonuclease VIII-like 1 (E. coli) | -0.3 |
| ZBED8 | zinc finger, BED-type containing 8 | -0.3 |
| CDK18 | cyclin-dependent kinase 18 | -0.3 |
| LYPLA2 | lysophospholipase II | -0.29 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.29 |
| SULF2 | sulfatase 2 | -0.29 |
| TMEM184B | transmembrane protein 184B | -0.29 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 | -0.29 |
| FBXO10 | F-box protein 10 | -0.29 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.29 |
| NCBP2AS2 | NCBP2 antisense 2 (head to head) | -0.28 |
| FAM241A | family with sequence similarity 241 member A | -0.28 |
| MAPK7 | mitogen-activated protein kinase 7 | -0.28 |
| BMP4 | bone morphogenetic protein 4 | -0.28 |
| METTL9 | methyltransferase like 9 | -0.28 |
| CCDC158 | coiled-coil domain containing 158 | -0.27 |
| ARMC5 | armadillo repeat containing 5 | -0.27 |
| FAM126B | family with sequence similarity 126, member B | -0.27 |
| EVA1C | eva-1 homolog C (C. elegans) | -0.27 |
| ALKBH7 | alkB, alkylation repair homolog 7 (E. coli) | -0.27 |
