| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elimusertib hydrochloride perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elimusertib hydrochloride_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.288822 |
| VIM | vimentin | 0.187168 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.155634 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.117824 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.105449 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.100811 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0949044 |
| ACTN4 | actinin, alpha 4 | 0.0795746 |
| FLNA | filamin A, alpha | 0.0754423 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0744108 |
| RNF213 | ring finger protein 213 | 0.0740104 |
| MYO10 | myosin X | 0.0662465 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0652751 |
| CMIP | c-Maf inducing protein | 0.064539 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0630059 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0621671 |
| PLEC | plectin | 0.0611863 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0607342 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0589609 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0549948 |
| LDHA | lactate dehydrogenase A | 0.0548508 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0547943 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0546062 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0523723 |
| CA12 | carbonic anhydrase XII | 0.0509962 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0492095 |
| KRT18 | keratin 18, type I | 0.0490919 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0487471 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0448668 |
| MYOF | myoferlin | 0.0443498 |
| EGFR | epidermal growth factor receptor | 0.0433309 |
| PKM | pyruvate kinase, muscle | 0.0416874 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0414977 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0412798 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0410247 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.039531 |
| FN1 | fibronectin 1 | 0.0394804 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0394599 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0386165 |
| DSPP | dentin sialophosphoprotein | 0.037877 |
| MYO1E | myosin IE | 0.0361269 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0359413 |
| ANXA4 | annexin A4 | 0.0356716 |
| EFNA1 | ephrin-A1 | 0.035469 |
| BICC1 | BicC family RNA binding protein 1 | 0.0350892 |
| DST | dystonin | 0.0346019 |
| HDGF | hepatoma-derived growth factor | 0.0344926 |
| CAVIN1 | caveolae associated protein 1 | 0.0338058 |
| RPL4 | ribosomal protein L4 | 0.0336174 |
| RPS4X | ribosomal protein S4, X-linked | 0.0333668 |
| ACLY | ATP citrate lyase | 0.0332642 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0330495 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0330438 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.033036 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0327026 |
| PCBP2 | poly(rC) binding protein 2 | 0.0323671 |
| KYNU | kynureninase | 0.032184 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0316691 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0312219 |
| SMAD3 | SMAD family member 3 | 0.0307693 |
| LMNA | lamin A/C | 0.0306085 |
| FAT1 | FAT atypical cadherin 1 | 0.0306063 |
| RBPMS | RNA binding protein with multiple splicing | 0.0301229 |
| LMO7 | LIM domain 7 | 0.0295927 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0294429 |
| CANX | calnexin | 0.0293669 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.0290546 |
| MYO1B | myosin IB | 0.0289761 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0284783 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0274638 |
| RPL7 | ribosomal protein L7 | 0.0272832 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0268616 |
| PDLIM5 | PDZ and LIM domain 5 | 0.026674 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0260474 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0254552 |
| SEPTIN9 | septin 9 | 0.0254073 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0252676 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0251776 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0249659 |
| FAM107B | family with sequence similarity 107, member B | 0.0246546 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0244765 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0242231 |
| FOSL2 | FOS-like antigen 2 | 0.0242063 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0240991 |
| MAP7 | microtubule-associated protein 7 | 0.0240042 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.023956 |
| AUTS2 | autism susceptibility candidate 2 | 0.0239347 |
| PALLD | palladin, cytoskeletal associated protein | 0.0236858 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0235741 |
| ATF4 | activating transcription factor 4 | 0.0232283 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0231916 |
| OPTN | optineurin | 0.0231618 |
| RPS17 | ribosomal protein S17 | 0.0231261 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0228347 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0227516 |
| SET | SET nuclear proto-oncogene | 0.0225418 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0224404 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0224255 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0223552 |
| TNS3 | tensin 3 | 0.0223406 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.136768 |
| FTL | ferritin, light polypeptide | -0.126214 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.121914 |
| STC1 | stanniocalcin 1 | -0.104053 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0978333 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0972511 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0913403 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0876016 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0818447 |
| MT2A | metallothionein 2A | -0.0808381 |
| EFNA5 | ephrin-A5 | -0.0807186 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0779533 |
| PDE10A | phosphodiesterase 10A | -0.0760543 |
| MT1X | metallothionein 1X | -0.0755743 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0726364 |
| OSMR | oncostatin M receptor | -0.0707227 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0662021 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0657896 |
| USP3 | ubiquitin specific peptidase 3 | -0.0620576 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0611629 |
| ANXA2 | annexin A2 | -0.0566753 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0542643 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0525374 |
| ACTG1 | actin gamma 1 | -0.0518385 |
| FMNL2 | formin-like 2 | -0.051781 |
| EGR1 | early growth response 1 | -0.0506063 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0499008 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0492474 |
| VMP1 | vacuole membrane protein 1 | -0.0490896 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0487983 |
| ASPH | aspartate beta-hydroxylase | -0.0481925 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0473551 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0473331 |
| TMSB10 | thymosin beta 10 | -0.0464759 |
| RIN2 | Ras and Rab interactor 2 | -0.0462142 |
| RTN4 | reticulon 4 | -0.0462141 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0454419 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.045266 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0447314 |
| EHBP1 | EH domain binding protein 1 | -0.0446083 |
| NF1 | neurofibromin 1 | -0.0444776 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0444414 |
| RAI14 | retinoic acid induced 14 | -0.0410606 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0410156 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.040785 |
| RPS19 | ribosomal protein S19 | -0.0406194 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0399899 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0398495 |
| ECT2 | epithelial cell transforming 2 | -0.0394535 |
| ITGB5 | integrin, beta 5 | -0.0390759 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0389115 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0382903 |
| SPAG9 | sperm associated antigen 9 | -0.0378775 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.036784 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0367131 |
| GOLGA4 | golgin A4 | -0.0366714 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0365223 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0364566 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0359719 |
| CCDC88A | coiled-coil domain containing 88A | -0.0357772 |
| HELZ | helicase with zinc finger | -0.0357071 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0352944 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0349593 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0346117 |
| SLC38A2 | solute carrier family 38, member 2 | -0.034559 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0344428 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0341945 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0337183 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0329547 |
| SBF2 | SET binding factor 2 | -0.0327236 |
| KRT81 | keratin 81, type II | -0.0326872 |
| RASA2 | RAS p21 protein activator 2 | -0.0323494 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0322439 |
| CEP95 | centrosomal protein 95kDa | -0.0321591 |
| ATG7 | autophagy related 7 | -0.0321488 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0319248 |
| RPS24 | ribosomal protein S24 | -0.0318326 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0318139 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.031613 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0316074 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0313421 |
| HMGA1 | high mobility group AT-hook 1 | -0.0312309 |
| CD44 | CD44 molecule (Indian blood group) | -0.0310613 |
| WDR45B | WD repeat domain 45B | -0.0308646 |
| BMERB1 | bMERB domain containing 1 | -0.0307131 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0304418 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0297746 |
| RBM39 | RNA binding motif protein 39 | -0.0296844 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0290516 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0288742 |
| THOC2 | THO complex 2 | -0.0285523 |
| PFN1 | profilin 1 | -0.0284917 |
| ATP13A3 | ATPase type 13A3 | -0.028422 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0278909 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0276657 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0267224 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0259914 |
| PDE8A | phosphodiesterase 8A | -0.0256922 |
| HMGA2 | high mobility group AT-hook 2 | -0.0256753 |
| RPLP1 | ribosomal protein, large, P1 | -0.0256008 |
