| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elimusertib hydrochloride perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Elimusertib hydrochloride_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.253451 |
| VEGFA | vascular endothelial growth factor A | 0.125889 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.122834 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0968088 |
| CANX | calnexin | 0.0716134 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0664585 |
| TMSB4X | thymosin beta 4, X-linked | 0.0598422 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0549147 |
| UTRN | utrophin | 0.0535744 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0526554 |
| FLNA | filamin A, alpha | 0.0497155 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0467749 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0450014 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0410764 |
| CTBP2 | C-terminal binding protein 2 | 0.0410524 |
| EZR | ezrin | 0.0402714 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0399668 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.03921 |
| AHNAK | AHNAK nucleoprotein | 0.0378048 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0362927 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0358925 |
| PKM | pyruvate kinase, muscle | 0.0353334 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0352819 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0345643 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0335348 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0332308 |
| LDHA | lactate dehydrogenase A | 0.0331854 |
| MEST | mesoderm specific transcript | 0.0330536 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0326988 |
| MYOF | myoferlin | 0.0326139 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0319529 |
| BCOR | BCL6 corepressor | 0.0315516 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.031263 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0312359 |
| NDRG1 | N-myc downstream regulated 1 | 0.0308298 |
| RPS4X | ribosomal protein S4, X-linked | 0.0308087 |
| RHOA | ras homolog family member A | 0.0305905 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0301995 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0294508 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0292485 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0291291 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0283764 |
| TPI1 | triosephosphate isomerase 1 | 0.0283329 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0282938 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0280401 |
| LOXL2 | lysyl oxidase-like 2 | 0.0278637 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0277781 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0275671 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0275555 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0272895 |
| CEP250 | centrosomal protein 250kDa | 0.0271184 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0269174 |
| H1-2 | H1.2 linker histone, cluster member | 0.0268536 |
| TNS3 | tensin 3 | 0.0266595 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0265887 |
| OGA | O-GlcNAcase | 0.02655 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0264117 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0264003 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0263645 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0263022 |
| HDLBP | high density lipoprotein binding protein | 0.0262819 |
| TLN1 | talin 1 | 0.0261424 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0255788 |
| DST | dystonin | 0.0253513 |
| CHD3 | chromodomain helicase DNA binding protein 3 | 0.0251899 |
| XPO1 | exportin 1 | 0.0249692 |
| INTS6 | integrator complex subunit 6 | 0.0246844 |
| MALSU1 | mitochondrial assembly of ribosomal large subunit 1 | 0.0245042 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0244892 |
| BBX | bobby sox homolog (Drosophila) | 0.0244319 |
| MCL1 | myeloid cell leukemia 1 | 0.0240977 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0240541 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0240297 |
| CENPF | centromere protein F, 350/400kDa | 0.0238919 |
| KIF1B | kinesin family member 1B | 0.0237099 |
| NSD3 | nuclear receptor binding SET domain protein 3 | 0.0236729 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0234884 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0234368 |
| TPM4 | tropomyosin 4 | 0.0232718 |
| HYOU1 | hypoxia up-regulated 1 | 0.0231432 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0230587 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.022791 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0227684 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0227437 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0226703 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0226585 |
| WWC2 | WW and C2 domain containing 2 | 0.0225467 |
| STAG2 | stromal antigen 2 | 0.0221409 |
| ENO1 | enolase 1, (alpha) | 0.022138 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.022021 |
| RPL4 | ribosomal protein L4 | 0.0218262 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0216594 |
| UBC | ubiquitin C | 0.0215093 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.0214485 |
| SIK3 | SIK family kinase 3 | 0.0213538 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0210999 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 0.0209375 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0208255 |
| ADAR | adenosine deaminase, RNA-specific | 0.0206743 |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 | 0.0205542 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.182167 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.136917 |
| SEPTIN11 | septin 11 | -0.114878 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.105558 |
| MEOX2 | mesenchyme homeobox 2 | -0.0963797 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0615847 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0608318 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0579459 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0563861 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.055507 |
| ITGAV | integrin, alpha V | -0.0550555 |
| COL1A2 | collagen, type I, alpha 2 | -0.0547336 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0501335 |
| SRPK2 | SRSF protein kinase 2 | -0.0479463 |
| PDGFC | platelet derived growth factor C | -0.0459463 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0448304 |
| RPLP1 | ribosomal protein, large, P1 | -0.0447502 |
| NFIA | nuclear factor I/A | -0.0440451 |
| NBEA | neurobeachin | -0.0439101 |
| KAZN | kazrin, periplakin interacting protein | -0.0425372 |
| RPL35A | ribosomal protein L35a | -0.040821 |
| JMJD1C | jumonji domain containing 1C | -0.0403837 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0403449 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0388631 |
| CALD1 | caldesmon 1 | -0.0388099 |
| FTL | ferritin, light polypeptide | -0.0375915 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0367401 |
| RPS12 | ribosomal protein S12 | -0.0367083 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0367023 |
| RPS24 | ribosomal protein S24 | -0.0364133 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0363235 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0361577 |
| CENPE | centromere protein E, 312kDa | -0.0361302 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0358493 |
| PCM1 | pericentriolar material 1 | -0.0358419 |
| QKI | QKI, KH domain containing, RNA binding | -0.034965 |
| CLINT1 | clathrin interactor 1 | -0.0347332 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0343171 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.0336314 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0333905 |
| RHEB | Ras homolog enriched in brain | -0.0332553 |
| OLA1 | Obg-like ATPase 1 | -0.0328197 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.0323828 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0321774 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0320336 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0319627 |
| RPS6 | ribosomal protein S6 | -0.0316764 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.0314507 |
| USP3 | ubiquitin specific peptidase 3 | -0.0312213 |
| ENAH | enabled homolog (Drosophila) | -0.0309713 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0305748 |
| WTAP | Wilms tumor 1 associated protein | -0.0300311 |
| KLHDC10 | kelch domain containing 10 | -0.0296621 |
| RFX7 | regulatory factor X, 7 | -0.029452 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0289947 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0288886 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0288178 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0286088 |
| THOC2 | THO complex 2 | -0.0284703 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0284387 |
| RPL36 | ribosomal protein L36 | -0.0280287 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0278895 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0277584 |
| B2M | beta-2-microglobulin | -0.0275438 |
| RPL37A | ribosomal protein L37a | -0.0273323 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0272825 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0271202 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.027106 |
| RNF145 | ring finger protein 145 | -0.0269944 |
| RNF130 | ring finger protein 130 | -0.0268784 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0267889 |
| RPLP2 | ribosomal protein, large, P2 | -0.0267365 |
| TCERG1 | transcription elongation regulator 1 | -0.0266 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0264808 |
| TMSB10 | thymosin beta 10 | -0.0264306 |
| RPL26 | ribosomal protein L26 | -0.0262835 |
| MAGED1 | melanoma antigen family D1 | -0.0261183 |
| RPL37 | ribosomal protein L37 | -0.0260222 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0259877 |
| PHF14 | PHD finger protein 14 | -0.0259179 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0258954 |
| RTN4 | reticulon 4 | -0.0258882 |
| HMGA2 | high mobility group AT-hook 2 | -0.02583 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0258165 |
| HDAC8 | histone deacetylase 8 | -0.0257958 |
| FBXO11 | F-box protein 11 | -0.0257574 |
| WRN | Werner syndrome, RecQ helicase-like | -0.0257236 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0254777 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0254582 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0250897 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0250153 |
| RPL34 | ribosomal protein L34 | -0.0249607 |
| COMMD10 | COMM domain containing 10 | -0.024944 |
| TNPO1 | transportin 1 | -0.0249196 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0248798 |
| CADM2 | cell adhesion molecule 2 | -0.0246339 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0245805 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0242786 |
| ETNK1 | ethanolamine kinase 1 | -0.024168 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0241273 |
