| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elimusertib hydrochloride perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Elimusertib hydrochloride_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.238287 |
| MUC17 | mucin 17, cell surface associated | 0.193766 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.161998 |
| LAMB3 | laminin, beta 3 | 0.136831 |
| VIM | vimentin | 0.113923 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0864325 |
| PGK1 | phosphoglycerate kinase 1 | 0.0816903 |
| DIAPH1 | diaphanous-related formin 1 | 0.0802851 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0794783 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.0736319 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | 0.0734692 |
| EFNA5 | ephrin-A5 | 0.0721669 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0685514 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0673193 |
| TXNIP | thioredoxin interacting protein | 0.0634169 |
| RNF213 | ring finger protein 213 | 0.0627565 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0622824 |
| PRELID2 | PRELI domain containing 2 | 0.0603998 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0595361 |
| SP100 | SP100 nuclear antigen | 0.0586498 |
| TGM2 | transglutaminase 2 | 0.0578276 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0574408 |
| PMM2 | phosphomannomutase 2 | 0.0564826 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0510267 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0497693 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0497473 |
| FAM13A | family with sequence similarity 13, member A | 0.0493273 |
| RRBP1 | ribosome binding protein 1 | 0.0491483 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0487865 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0487093 |
| CANX | calnexin | 0.0460912 |
| DSPP | dentin sialophosphoprotein | 0.0457794 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0440696 |
| HLA-E | major histocompatibility complex, class I, E | 0.0434164 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0431052 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0425377 |
| KRT18 | keratin 18, type I | 0.0411078 |
| ACTN4 | actinin, alpha 4 | 0.0410685 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.039818 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0397133 |
| KLK10 | kallikrein-related peptidase 10 | 0.0388702 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.038818 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0382979 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0378117 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0377373 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0369115 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0368858 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0365496 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0365133 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0360242 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0351011 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0348662 |
| UBC | ubiquitin C | 0.0344954 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0342575 |
| SVIL | supervillin | 0.0338718 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0327351 |
| LDHA | lactate dehydrogenase A | 0.032628 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0325565 |
| FAM107B | family with sequence similarity 107, member B | 0.0324123 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0323032 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.032175 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.032171 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0312676 |
| HDLBP | high density lipoprotein binding protein | 0.0311284 |
| MXI1 | MAX interactor 1, dimerization protein | 0.030934 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0308325 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0307586 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0303784 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0299947 |
| MCL1 | myeloid cell leukemia 1 | 0.0299688 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0297384 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0295055 |
| AHNAK | AHNAK nucleoprotein | 0.0292901 |
| CTBP2 | C-terminal binding protein 2 | 0.0288218 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0287999 |
| TMC5 | transmembrane channel-like 5 | 0.0284563 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0283511 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.0281348 |
| CLMP | CXADR-like membrane protein | 0.0279851 |
| FLNA | filamin A, alpha | 0.02781 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0274615 |
| PLSCR1 | phospholipid scramblase 1 | 0.0271829 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0271436 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0270929 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0267125 |
| MYOF | myoferlin | 0.0262878 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.026042 |
| KRT19 | keratin 19, type I | 0.02575 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0255536 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0254797 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.025464 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0253255 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0250542 |
| HDAC9 | histone deacetylase 9 | 0.0249983 |
| PLEC | plectin | 0.024702 |
| EFNB2 | ephrin-B2 | 0.0246951 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0245952 |
| EZR | ezrin | 0.0244624 |
| ADAR | adenosine deaminase, RNA-specific | 0.0243484 |
| TMEM263 | transmembrane protein 263 | 0.0243046 |
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | -0.177863 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.120657 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0991348 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0958464 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0944185 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0839977 |
| RTN4 | reticulon 4 | -0.0796025 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0771357 |
| ITGA6 | integrin, alpha 6 | -0.0746358 |
| HMGA1 | high mobility group AT-hook 1 | -0.0731523 |
| ASPH | aspartate beta-hydroxylase | -0.0707214 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0660494 |
| ACTG1 | actin gamma 1 | -0.0642484 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0625198 |
| LAMA4 | laminin, alpha 4 | -0.0616855 |
| RPL37A | ribosomal protein L37a | -0.0598678 |
| FOSL1 | FOS-like antigen 1 | -0.0594659 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0527079 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0518476 |
| SERTAD2 | SERTA domain containing 2 | -0.0516026 |
| RPS12 | ribosomal protein S12 | -0.0461756 |
| RPS3 | ribosomal protein S3 | -0.0454068 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0453623 |
| RPS2 | ribosomal protein S2 | -0.0441736 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0439958 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0435612 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0431198 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.041253 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0407228 |
| CORO1C | coronin, actin binding protein, 1C | -0.040006 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0392014 |
| PCBP2 | poly(rC) binding protein 2 | -0.0384244 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0383435 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0382727 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0381729 |
| VCAN | versican | -0.0374045 |
| NEK7 | NIMA-related kinase 7 | -0.0373856 |
| RCOR1 | REST corepressor 1 | -0.0362425 |
| TXNRD1 | thioredoxin reductase 1 | -0.0359511 |
| EPCAM | epithelial cell adhesion molecule | -0.0357744 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0357137 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0355592 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0343395 |
| TMEM41B | transmembrane protein 41B | -0.0342768 |
| TOP1 | topoisomerase (DNA) I | -0.0341364 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0338175 |
| FOXO3 | forkhead box O3 | -0.0337904 |
| RPL11 | ribosomal protein L11 | -0.0337764 |
| SPAG9 | sperm associated antigen 9 | -0.033443 |
| GDA | guanine deaminase | -0.033276 |
| RPL31 | ribosomal protein L31 | -0.0331026 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0329496 |
| CCNL1 | cyclin L1 | -0.0328782 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0324683 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0319415 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0316498 |
| USP12 | ubiquitin specific peptidase 12 | -0.0316434 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0314134 |
| DSTN | destrin (actin depolymerizing factor) | -0.030769 |
| RPL30 | ribosomal protein L30 | -0.0305516 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.030501 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.0304729 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0303573 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0300622 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0296662 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0295147 |
| ITGB4 | integrin, beta 4 | -0.0288315 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0286613 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.0283732 |
| RPLP2 | ribosomal protein, large, P2 | -0.0283713 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0283124 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0278165 |
| CCDC88A | coiled-coil domain containing 88A | -0.0278133 |
| SLMAP | sarcolemma associated protein | -0.0277847 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.027242 |
| B2M | beta-2-microglobulin | -0.0271553 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0270864 |
| RPS29 | ribosomal protein S29 | -0.0266176 |
| MED13L | mediator complex subunit 13-like | -0.0263753 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0263273 |
| FTL | ferritin, light polypeptide | -0.0262565 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0262195 |
| RPL9 | ribosomal protein L9 | -0.0261153 |
| RPL26 | ribosomal protein L26 | -0.0261055 |
| SBF2 | SET binding factor 2 | -0.0260946 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0257482 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0253831 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0253635 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | -0.0252621 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0251728 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0249998 |
| PTMA | prothymosin, alpha | -0.0249545 |
| EGR1 | early growth response 1 | -0.0249173 |
| PTEN | phosphatase and tensin homolog | -0.0248976 |
| WASF2 | WAS protein family, member 2 | -0.0248797 |
| RPL5 | ribosomal protein L5 | -0.0247794 |
| NUP58 | nucleoporin 58 | -0.0246711 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0246619 |
| RHEB | Ras homolog enriched in brain | -0.0246338 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0245713 |
