| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elimusertib hydrochloride perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Elimusertib hydrochloride_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF608 | zinc finger protein 608 | 0.0994726 |
| COL5A2 | collagen, type V, alpha 2 | 0.0699277 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0667157 |
| VCL | vinculin | 0.0651571 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0577436 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0565595 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0531143 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0455945 |
| CDH18 | cadherin 18, type 2 | 0.0422819 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0420736 |
| CEP250 | centrosomal protein 250kDa | 0.0400871 |
| DHFR | dihydrofolate reductase | 0.0393485 |
| FLNA | filamin A, alpha | 0.0391096 |
| RIGI | RNA sensor RIG-I | 0.0368276 |
| RPS4X | ribosomal protein S4, X-linked | 0.0367967 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0357616 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0338585 |
| NBEAL1 | neurobeachin-like 1 | 0.0327327 |
| BNC2 | basonuclin 2 | 0.0319513 |
| RNF213 | ring finger protein 213 | 0.0317458 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.031517 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0286972 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0286688 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0263342 |
| KIF1B | kinesin family member 1B | 0.0262784 |
| MKI67 | marker of proliferation Ki-67 | 0.0262047 |
| ADAR | adenosine deaminase, RNA-specific | 0.0254013 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0241597 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0241024 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0238644 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0237409 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0229631 |
| ATF4 | activating transcription factor 4 | 0.0229338 |
| ASPH | aspartate beta-hydroxylase | 0.022627 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0226134 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0223722 |
| PCNX4 | pecanex 4 | 0.0222864 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0213002 |
| CANX | calnexin | 0.0212681 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.021258 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0210519 |
| RPL7 | ribosomal protein L7 | 0.0208659 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0208477 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0207227 |
| SMAD6 | SMAD family member 6 | 0.0207098 |
| ALMS1 | Alstrom syndrome protein 1 | 0.0206583 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0206034 |
| SIK2 | salt-inducible kinase 2 | 0.0200028 |
| SIK3 | SIK family kinase 3 | 0.0199123 |
| ATP5F1A | ATP synthase F1 subunit alpha | 0.0195259 |
| ATG10 | autophagy related 10 | 0.0194821 |
| PMP22 | peripheral myelin protein 22 | 0.0192882 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0190802 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0189412 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.018912 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0188408 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0188353 |
| RNF187 | ring finger protein 187 | 0.0187422 |
| RPL14 | ribosomal protein L14 | 0.0185924 |
| CEP112 | centrosomal protein 112kDa | 0.0182633 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0179962 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0178367 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0176884 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0175831 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0175321 |
| DUSP16 | dual specificity phosphatase 16 | 0.0175218 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0175194 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0173176 |
| CABIN1 | calcineurin binding protein 1 | 0.0173018 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0172984 |
| HDAC4 | histone deacetylase 4 | 0.016855 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0168381 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0167835 |
| WWOX | WW domain containing oxidoreductase | 0.0167767 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0167217 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0167016 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0165642 |
| INTS6 | integrator complex subunit 6 | 0.0164469 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0162758 |
| OGFR | opioid growth factor receptor | 0.0162152 |
| AEBP2 | AE binding protein 2 | 0.0161939 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0161588 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0161044 |
| CHD3 | chromodomain helicase DNA binding protein 3 | 0.0160467 |
| NRDC | nardilysin convertase | 0.0160413 |
| MNMIP1 | manchette microtubule inner protein 1 | 0.0159939 |
| TPM4 | tropomyosin 4 | 0.0159853 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0157075 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0156495 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0156338 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0155992 |
| JUN | jun proto-oncogene | 0.01556 |
| RHOB | ras homolog family member B | 0.0154535 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0154386 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0154283 |
| PHF3 | PHD finger protein 3 | 0.0154115 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0152873 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0152577 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0152451 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.01514 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.178827 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.15435 |
| NPAS3 | neuronal PAS domain protein 3 | -0.114932 |
| RAD51B | RAD51 paralog B | -0.107077 |
| TENM3 | teneurin transmembrane protein 3 | -0.0943276 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0910665 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0834023 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.081997 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0707564 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0670605 |
| NEBL | nebulette | -0.0667794 |
| ACTG1 | actin gamma 1 | -0.0664329 |
| PTMA | prothymosin, alpha | -0.0658612 |
| RPS6 | ribosomal protein S6 | -0.0623527 |
| TMSB10 | thymosin beta 10 | -0.0579019 |
| UBC | ubiquitin C | -0.0554004 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0546843 |
| RPS21 | ribosomal protein S21 | -0.0516533 |
| EGR1 | early growth response 1 | -0.05089 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0494553 |
| WDR45B | WD repeat domain 45B | -0.0492232 |
| FMNL2 | formin-like 2 | -0.0482965 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0478971 |
| RBM25 | RNA binding motif protein 25 | -0.0459088 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0457596 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0447841 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0433875 |
| NUP58 | nucleoporin 58 | -0.0426032 |
| RPS5 | ribosomal protein S5 | -0.042562 |
| RPS24 | ribosomal protein S24 | -0.0422751 |
| RPS8 | ribosomal protein S8 | -0.0421041 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0415086 |
| RPL32 | ribosomal protein L32 | -0.0412194 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0407115 |
| ZNF292 | zinc finger protein 292 | -0.0406514 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0403906 |
| PARD3 | par-3 family cell polarity regulator | -0.0401337 |
| SRPK2 | SRSF protein kinase 2 | -0.0401062 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0400689 |
| RPS27A | ribosomal protein S27a | -0.0397587 |
| RPS19 | ribosomal protein S19 | -0.0394995 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0392297 |
| RPL11 | ribosomal protein L11 | -0.0392128 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0385761 |
| PFN1 | profilin 1 | -0.0384558 |
| RPL35A | ribosomal protein L35a | -0.0381971 |
| PHIP | pleckstrin homology domain interacting protein | -0.0381094 |
| RPLP2 | ribosomal protein, large, P2 | -0.0377071 |
| RPL28 | ribosomal protein L28 | -0.037282 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0372627 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0370396 |
| ENO1 | enolase 1, (alpha) | -0.0370104 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0366395 |
| HMGA1 | high mobility group AT-hook 1 | -0.0362644 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0360061 |
| RPLP1 | ribosomal protein, large, P1 | -0.0354802 |
| ENAH | enabled homolog (Drosophila) | -0.0354113 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0353111 |
| RPL37A | ribosomal protein L37a | -0.0352023 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0349015 |
| RPS11 | ribosomal protein S11 | -0.0348021 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0345484 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0341257 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0336466 |
| ZNF217 | zinc finger protein 217 | -0.0335528 |
| MYL12B | myosin, light chain 12B, regulatory | -0.033545 |
| RPL31 | ribosomal protein L31 | -0.0333738 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0331184 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0328761 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0327454 |
| RPL12 | ribosomal protein L12 | -0.0325414 |
| SMYD3 | SET and MYND domain containing 3 | -0.0322548 |
| RPL5 | ribosomal protein L5 | -0.0319693 |
| RPL34 | ribosomal protein L34 | -0.0312109 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0308347 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0306189 |
| ZFP64 | ZFP64 zinc finger protein | -0.0304962 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0304506 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0303654 |
| RPS13 | ribosomal protein S13 | -0.0303138 |
| RPS29 | ribosomal protein S29 | -0.0302325 |
| VMP1 | vacuole membrane protein 1 | -0.0301411 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0297502 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0295734 |
| RPL26 | ribosomal protein L26 | -0.029482 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0292253 |
| EFNA5 | ephrin-A5 | -0.0291132 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0289014 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0285126 |
| RFX7 | regulatory factor X, 7 | -0.0282222 |
| IPO7 | importin 7 | -0.0281696 |
| FTL | ferritin, light polypeptide | -0.0280594 |
| NGLY1 | N-glycanase 1 | -0.0278593 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0277922 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0275871 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0275354 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0274736 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0272794 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0270372 |
| RPS25 | ribosomal protein S25 | -0.0268823 |
