| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elimusertib hydrochloride perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Elimusertib hydrochloride_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| APOL1 | apolipoprotein L, 1 | 0.12472 |
| FNDC3B | fibronectin type III domain containing 3B | 0.120938 |
| CFB | complement factor B | 0.103034 |
| RNF213 | ring finger protein 213 | 0.0942935 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0927157 |
| TGM2 | transglutaminase 2 | 0.0801973 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0773863 |
| MX1 | MX dynamin-like GTPase 1 | 0.0767069 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0760264 |
| SMAD3 | SMAD family member 3 | 0.0718583 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0702231 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0633193 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0620103 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0619665 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0585075 |
| MUC16 | mucin 16, cell surface associated | 0.0553434 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0544641 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0527593 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0517201 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0505347 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0479415 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.046221 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0458398 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0452186 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0450486 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0450274 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0439229 |
| KYNU | kynureninase | 0.0438 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0436516 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0421603 |
| VEGFA | vascular endothelial growth factor A | 0.0417711 |
| RIGI | RNA sensor RIG-I | 0.0414936 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0406746 |
| C3 | complement component 3 | 0.0405109 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0387467 |
| MX2 | MX dynamin-like GTPase 2 | 0.0384694 |
| CP | ceruloplasmin (ferroxidase) | 0.038086 |
| UBC | ubiquitin C | 0.0378508 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0378353 |
| APOL2 | apolipoprotein L, 2 | 0.0369381 |
| EFNA5 | ephrin-A5 | 0.0363615 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0354171 |
| MYO1E | myosin IE | 0.0350794 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0346288 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0341109 |
| RAD51B | RAD51 paralog B | 0.0335639 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.0331352 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0329425 |
| SEPTIN9 | septin 9 | 0.0328494 |
| KIAA1217 | KIAA1217 | 0.0320558 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0316883 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.031431 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.031319 |
| FAM107B | family with sequence similarity 107, member B | 0.0308554 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0308226 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0308208 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0303001 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0302384 |
| PMP22 | peripheral myelin protein 22 | 0.0288495 |
| DUOX2 | dual oxidase 2 | 0.0284487 |
| IRF1 | interferon regulatory factor 1 | 0.0281714 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0279341 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0274481 |
| PLEC | plectin | 0.0273916 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0266892 |
| TMC5 | transmembrane channel-like 5 | 0.0258928 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0258219 |
| ARRDC3 | arrestin domain containing 3 | 0.0255959 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0252324 |
| SP100 | SP100 nuclear antigen | 0.0248029 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0247517 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0247462 |
| APP | amyloid beta (A4) precursor protein | 0.0246937 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0241081 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0240176 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.024009 |
| ADAR | adenosine deaminase, RNA-specific | 0.0239414 |
| JUN | jun proto-oncogene | 0.0237158 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0233494 |
| HKDC1 | hexokinase domain containing 1 | 0.0231514 |
| FGB | fibrinogen beta chain | 0.0230759 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0230614 |
| CMIP | c-Maf inducing protein | 0.0226658 |
| SHROOM3 | shroom family member 3 | 0.0224039 |
| SAMD9L | sterile alpha motif domain containing 9-like | 0.0223528 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0223001 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0222767 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0222436 |
| HLA-E | major histocompatibility complex, class I, E | 0.0219952 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0219753 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0219636 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0219444 |
| NOTCH2 | notch 2 | 0.021707 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0217013 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0215933 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0212564 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0211558 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | 0.0211135 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0208584 |
| FOSL2 | FOS-like antigen 2 | 0.0208376 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.162638 |
| FTL | ferritin, light polypeptide | -0.145327 |
| MT2A | metallothionein 2A | -0.124451 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.109443 |
| PTMA | prothymosin, alpha | -0.107469 |
| HLA-B | major histocompatibility complex, class I, B | -0.0912051 |
| ACTG1 | actin gamma 1 | -0.090271 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0895086 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0889825 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0766192 |
| NDRG1 | N-myc downstream regulated 1 | -0.0764232 |
| PGK1 | phosphoglycerate kinase 1 | -0.074507 |
| ANXA2 | annexin A2 | -0.0711583 |
| ASPH | aspartate beta-hydroxylase | -0.0711462 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0694172 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0665563 |
| LAMB3 | laminin, beta 3 | -0.0662509 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0657559 |
| POTEF | POTE ankyrin domain family, member F | -0.0648104 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0646654 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0614257 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0596215 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0591398 |
| MMP7 | matrix metallopeptidase 7 | -0.0539564 |
| B2M | beta-2-microglobulin | -0.0523729 |
| RTN4 | reticulon 4 | -0.0522087 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0514724 |
| RPL37A | ribosomal protein L37a | -0.0513781 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0507323 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0491983 |
| MT1X | metallothionein 1X | -0.0484967 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0479232 |
| IER3 | immediate early response 3 | -0.0470723 |
| RPS29 | ribosomal protein S29 | -0.0470019 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0465598 |
| MAP1B | microtubule-associated protein 1B | -0.0463337 |
| RPL35A | ribosomal protein L35a | -0.0457633 |
| RPL11 | ribosomal protein L11 | -0.0451817 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0450628 |
| RPL19 | ribosomal protein L19 | -0.044926 |
| FAM162A | family with sequence similarity 162, member A | -0.0446928 |
| FLNB | filamin B, beta | -0.0435154 |
| S100A6 | S100 calcium binding protein A6 | -0.0432987 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0432208 |
| SPAG9 | sperm associated antigen 9 | -0.0422341 |
| HMGA1 | high mobility group AT-hook 1 | -0.0420718 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0420667 |
| CSTB | cystatin B (stefin B) | -0.0419995 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0418027 |
| ITGA6 | integrin, alpha 6 | -0.0412289 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0410987 |
| VDAC1 | voltage-dependent anion channel 1 | -0.039844 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0395073 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0392314 |
| RPL31 | ribosomal protein L31 | -0.0391648 |
| ENO1 | enolase 1, (alpha) | -0.038848 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0386083 |
| GNAS | GNAS complex locus | -0.0383818 |
| RPS19 | ribosomal protein S19 | -0.038055 |
| RPS25 | ribosomal protein S25 | -0.0380507 |
| RPS3 | ribosomal protein S3 | -0.0370544 |
| TMSB4X | thymosin beta 4, X-linked | -0.0368909 |
| MEF2A | myocyte enhancer factor 2A | -0.036442 |
| LAMC2 | laminin, gamma 2 | -0.0363087 |
| TPM4 | tropomyosin 4 | -0.0359647 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0359076 |
| RPLP1 | ribosomal protein, large, P1 | -0.0357818 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0357806 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0356577 |
| RBM39 | RNA binding motif protein 39 | -0.0356449 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0351932 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0351468 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0349449 |
| PLAU | plasminogen activator, urokinase | -0.0347387 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0344452 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0343803 |
| ANTXR2 | anthrax toxin receptor 2 | -0.034218 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0342105 |
| LAMA4 | laminin, alpha 4 | -0.0341509 |
| RPS24 | ribosomal protein S24 | -0.0337989 |
| WDR45B | WD repeat domain 45B | -0.0336978 |
| DSG2 | desmoglein 2 | -0.0334756 |
| RAI14 | retinoic acid induced 14 | -0.03336 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0331712 |
| FRMD5 | FERM domain containing 5 | -0.0329498 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0328861 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0326932 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.032603 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0325711 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0325573 |
| TMEM123 | transmembrane protein 123 | -0.0325035 |
| PARD3 | par-3 family cell polarity regulator | -0.0323495 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0323384 |
| FNBP1L | formin binding protein 1-like | -0.0315876 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0315119 |
| JMJD1C | jumonji domain containing 1C | -0.031509 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0311147 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0309716 |
| FAM13A | family with sequence similarity 13, member A | -0.0306332 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.0306101 |
