| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elimusertib hydrochloride perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elimusertib hydrochloride_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.187025 |
| VIM | vimentin | 0.108124 |
| TLE4 | transducin-like enhancer of split 4 | 0.0984029 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0981679 |
| RNF213 | ring finger protein 213 | 0.0737303 |
| PLPP1 | phospholipid phosphatase 1 | 0.0614611 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0614077 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0608297 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0578007 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0565481 |
| RPL23 | ribosomal protein L23 | 0.0512637 |
| FAM107B | family with sequence similarity 107, member B | 0.0505151 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0465754 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0455599 |
| SIK2 | salt-inducible kinase 2 | 0.0443808 |
| TRIB2 | tribbles pseudokinase 2 | 0.0415009 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0382522 |
| FN1 | fibronectin 1 | 0.03782 |
| RIGI | RNA sensor RIG-I | 0.0368083 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.036501 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0355531 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0354817 |
| GLCCI1 | glucocorticoid induced 1 | 0.0345776 |
| FLNA | filamin A, alpha | 0.0345468 |
| INTS6 | integrator complex subunit 6 | 0.0342983 |
| MX1 | MX dynamin-like GTPase 1 | 0.0340563 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0338538 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0335911 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0334061 |
| STK38L | serine/threonine kinase 38 like | 0.0333032 |
| MYO1E | myosin IE | 0.0331671 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0328922 |
| COL3A1 | collagen, type III, alpha 1 | 0.0328418 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0325231 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0323342 |
| VEGFA | vascular endothelial growth factor A | 0.0314768 |
| SYNPO2 | synaptopodin 2 | 0.0307328 |
| RPS3 | ribosomal protein S3 | 0.0307151 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.0305907 |
| SEPTIN9 | septin 9 | 0.0304433 |
| SP100 | SP100 nuclear antigen | 0.0303944 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0301617 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0292111 |
| FMN1 | formin 1 | 0.0289437 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0279856 |
| TUFT1 | tuftelin 1 | 0.0273524 |
| CALD1 | caldesmon 1 | 0.0272051 |
| HOMER1 | homer scaffolding protein 1 | 0.027017 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0267517 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0265489 |
| RPS4X | ribosomal protein S4, X-linked | 0.0262998 |
| ATF4 | activating transcription factor 4 | 0.0262975 |
| CALR | calreticulin | 0.025755 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0252749 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0251017 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0250586 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.024887 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0245582 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0245526 |
| TPM1 | tropomyosin 1 (alpha) | 0.0243716 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0243528 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0241185 |
| PALLD | palladin, cytoskeletal associated protein | 0.0239268 |
| RALYL | RALY RNA binding protein-like | 0.0236279 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0235299 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0234536 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0229248 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0227488 |
| AEBP2 | AE binding protein 2 | 0.0227099 |
| LIMA1 | LIM domain and actin binding 1 | 0.0226351 |
| MX2 | MX dynamin-like GTPase 2 | 0.0225635 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0223734 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.02208 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0217061 |
| GSE1 | Gse1 coiled-coil protein | 0.0216855 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0216738 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.021624 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0215237 |
| EGFR | epidermal growth factor receptor | 0.0214375 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0213668 |
| RGS4 | regulator of G-protein signaling 4 | 0.0212836 |
| RPL19 | ribosomal protein L19 | 0.0212385 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0211841 |
| SLFN5 | schlafen family member 5 | 0.0211156 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.021113 |
| FAT1 | FAT atypical cadherin 1 | 0.0208844 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.020856 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0208124 |
| ASPH | aspartate beta-hydroxylase | 0.0207209 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0206863 |
| CEP250 | centrosomal protein 250kDa | 0.020603 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0204643 |
| FERMT2 | fermitin family member 2 | 0.0203909 |
| RPL14 | ribosomal protein L14 | 0.0202827 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0198259 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0198212 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0198156 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0195042 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0194847 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0194802 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.332295 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.154814 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.129636 |
| NRG1 | neuregulin 1 | -0.116753 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0881568 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0860761 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0844936 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0808183 |
| MEIS2 | Meis homeobox 2 | -0.0802066 |
| LPIN1 | lipin 1 | -0.0747488 |
| FAM13A | family with sequence similarity 13, member A | -0.0715683 |
| HELZ | helicase with zinc finger | -0.0677676 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0666566 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0621867 |
| CENPF | centromere protein F, 350/400kDa | -0.058797 |
| PLAT | plasminogen activator, tissue | -0.0587031 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0586621 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0569408 |
| ZNF292 | zinc finger protein 292 | -0.056696 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0550923 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0534642 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0534595 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0532799 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0525044 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0506228 |
| PTK2 | protein tyrosine kinase 2 | -0.0505105 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0484721 |
| CLTC | clathrin, heavy chain (Hc) | -0.0481174 |
| WDR45B | WD repeat domain 45B | -0.0479612 |
| MAP1B | microtubule-associated protein 1B | -0.0473347 |
| LSAMP | limbic system-associated membrane protein | -0.0466924 |
| KLHL13 | kelch-like family member 13 | -0.0451231 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0447245 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | -0.0444329 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0443521 |
| DPH6 | diphthamine biosynthesis 6 | -0.0429105 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0424181 |
| PTMA | prothymosin, alpha | -0.0423174 |
| RTN4 | reticulon 4 | -0.0415091 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0407816 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0406408 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0404404 |
| SBF2 | SET binding factor 2 | -0.0399968 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0399468 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0397674 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0388322 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.037722 |
| OGA | O-GlcNAcase | -0.0375576 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0356019 |
| GLG1 | golgi glycoprotein 1 | -0.0348092 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0345986 |
| AHR | aryl hydrocarbon receptor | -0.0345612 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0345395 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0341865 |
| NEK7 | NIMA-related kinase 7 | -0.0339334 |
| SPAG9 | sperm associated antigen 9 | -0.033884 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0338602 |
| ENAH | enabled homolog (Drosophila) | -0.0335515 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | -0.0332194 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0330182 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0326771 |
| CDC27 | cell division cycle 27 | -0.0323678 |
| PTEN | phosphatase and tensin homolog | -0.0323487 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0323422 |
| DST | dystonin | -0.0321772 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0320309 |
| NDRG1 | N-myc downstream regulated 1 | -0.0320099 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0318076 |
| SUCO | SUN domain containing ossification factor | -0.0316508 |
| GOLGA4 | golgin A4 | -0.031603 |
| RNF145 | ring finger protein 145 | -0.03142 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.03137 |
| TPR | translocated promoter region, nuclear basket protein | -0.0310754 |
| USP3 | ubiquitin specific peptidase 3 | -0.0308474 |
| PARD3 | par-3 family cell polarity regulator | -0.0307418 |
| COL1A1 | collagen, type I, alpha 1 | -0.0307109 |
| FOXK2 | forkhead box K2 | -0.0306967 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0306634 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0305908 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0303048 |
| MEF2A | myocyte enhancer factor 2A | -0.0302201 |
| SETD5 | SET domain containing 5 | -0.0301819 |
| NF1 | neurofibromin 1 | -0.0301687 |
| CEP95 | centrosomal protein 95kDa | -0.0300135 |
| NOP58 | NOP58 ribonucleoprotein | -0.029592 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0295364 |
| PRR11 | proline rich 11 | -0.0295298 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0295059 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0295038 |
| CCND1 | cyclin D1 | -0.0293054 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0292683 |
| AOPEP | aminopeptidase O (putative) | -0.028985 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0287094 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0286056 |
| CEP170 | centrosomal protein 170kDa | -0.0285308 |
| MXI1 | MAX interactor 1, dimerization protein | -0.028506 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0284406 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0283719 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0282843 |
| HIP1 | huntingtin interacting protein 1 | -0.028178 |
