| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elimusertib hydrochloride perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Elimusertib hydrochloride_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.0863963 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0821155 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0653864 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0583146 |
| DST | dystonin | 0.0564297 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0559479 |
| SMAD3 | SMAD family member 3 | 0.0515076 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0480536 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0453284 |
| MLPH | melanophilin | 0.0450422 |
| INTS6 | integrator complex subunit 6 | 0.0446805 |
| PDZD8 | PDZ domain containing 8 | 0.0413341 |
| RNF213 | ring finger protein 213 | 0.0389701 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0381114 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0357521 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0356363 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0343325 |
| PLSCR2 | phospholipid scramblase 2 | 0.0325047 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0323038 |
| HKDC1 | hexokinase domain containing 1 | 0.0320969 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0318799 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0316482 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0313835 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0309738 |
| KIF16B | kinesin family member 16B | 0.0302644 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0302519 |
| FNIP2 | folliculin interacting protein 2 | 0.0296487 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.029234 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0282665 |
| MCU | mitochondrial calcium uniporter | 0.0267705 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0264467 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0262327 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0262 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0260538 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0256475 |
| VEGFA | vascular endothelial growth factor A | 0.0255105 |
| SEPTIN9 | septin 9 | 0.0250415 |
| MCL1 | myeloid cell leukemia 1 | 0.0248966 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | 0.0239668 |
| SIK3 | SIK family kinase 3 | 0.0237912 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0234113 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0232441 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0232349 |
| RND3 | Rho family GTPase 3 | 0.0228965 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0228697 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0227186 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0221147 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0218847 |
| TMC5 | transmembrane channel-like 5 | 0.0218259 |
| CDHR2 | cadherin-related family member 2 | 0.021632 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.021599 |
| TMEM65 | transmembrane protein 65 | 0.021411 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0214105 |
| AEBP2 | AE binding protein 2 | 0.0208012 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0207964 |
| MUC20 | mucin 20, cell surface associated | 0.0205971 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0205805 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0205374 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0202613 |
| KRT19 | keratin 19, type I | 0.0201979 |
| IRS2 | insulin receptor substrate 2 | 0.0201192 |
| UBAP2 | ubiquitin associated protein 2 | 0.0199188 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0198293 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0196642 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0195706 |
| APOL1 | apolipoprotein L, 1 | 0.0189877 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0186338 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.018606 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0184072 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0183598 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0181989 |
| KYNU | kynureninase | 0.0180863 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.0179892 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0176894 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0175932 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0174214 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0173988 |
| POU2F2 | POU class 2 homeobox 2 | 0.0172589 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0172288 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0171806 |
| JMJD1C | jumonji domain containing 1C | 0.0171319 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0170102 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.0169667 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0169343 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.016901 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.0168981 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0168914 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0168877 |
| CLOCK | clock circadian regulator | 0.016846 |
| NTN4 | netrin 4 | 0.0168434 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0168023 |
| GK | glycerol kinase | 0.0167493 |
| MYO5B | myosin VB | 0.0167072 |
| PHF3 | PHD finger protein 3 | 0.0166118 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0165631 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0165307 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0163236 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0162996 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0161015 |
| BSDC1 | BSD domain containing 1 | 0.016048 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0980718 |
| RUNX1 | runt-related transcription factor 1 | -0.0954644 |
| B2M | beta-2-microglobulin | -0.0919038 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0891186 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0766617 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0759979 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0751914 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0748954 |
| ITGA6 | integrin, alpha 6 | -0.0726121 |
| ANXA2 | annexin A2 | -0.067549 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0659514 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0658779 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0636648 |
| RBM39 | RNA binding motif protein 39 | -0.0603618 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0601927 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0600585 |
| HLA-B | major histocompatibility complex, class I, B | -0.0578895 |
| ATP11A | ATPase, class VI, type 11A | -0.0551225 |
| SPATA13 | spermatogenesis associated 13 | -0.0543201 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.053052 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0501532 |
| EGR1 | early growth response 1 | -0.0499355 |
| FTL | ferritin, light polypeptide | -0.0494449 |
| H1-0 | H1.0 linker histone | -0.0477331 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0464528 |
| PLSCR1 | phospholipid scramblase 1 | -0.0462952 |
| HLA-C | major histocompatibility complex, class I, C | -0.0459292 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0458229 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0452928 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0439304 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0434225 |
| RPL35A | ribosomal protein L35a | -0.0434179 |
| MEIS2 | Meis homeobox 2 | -0.0432215 |
| DIAPH3 | diaphanous-related formin 3 | -0.0424287 |
| MKI67 | marker of proliferation Ki-67 | -0.0422109 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0419868 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0417198 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.040848 |
| NCKAP5 | NCK-associated protein 5 | -0.0407379 |
| ABHD2 | abhydrolase domain containing 2 | -0.0405649 |
| RPS6 | ribosomal protein S6 | -0.0405367 |
| TMEM62 | transmembrane protein 62 | -0.0391712 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0388019 |
| XAF1 | XIAP associated factor 1 | -0.0386096 |
| SQSTM1 | sequestosome 1 | -0.0382426 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0380717 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0378548 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0378151 |
| NF1 | neurofibromin 1 | -0.0372372 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0364455 |
| PTMA | prothymosin, alpha | -0.0362683 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0361045 |
| CDK6 | cyclin-dependent kinase 6 | -0.0359823 |
| MECOM | MDS1 and EVI1 complex locus | -0.0351748 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0349447 |
| AHI1 | Abelson helper integration site 1 | -0.0347761 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0346683 |
| HDAC4 | histone deacetylase 4 | -0.0346278 |
| BRCA2 | breast cancer 2, early onset | -0.0342269 |
| CCNL1 | cyclin L1 | -0.0341374 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0341175 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0321354 |
| UBL3 | ubiquitin-like 3 | -0.0319176 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0319 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0317451 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0314083 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0313881 |
| TNS4 | tensin 4 | -0.0309498 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0308652 |
| HBS1L | HBS1-like translational GTPase | -0.030801 |
| CENPF | centromere protein F, 350/400kDa | -0.030562 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | -0.0305446 |
| EPHB2 | EPH receptor B2 | -0.030185 |
| FOXP1 | forkhead box P1 | -0.0300342 |
| TXNIP | thioredoxin interacting protein | -0.0299972 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0299713 |
| VMP1 | vacuole membrane protein 1 | -0.0298633 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0295929 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0295874 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.029501 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0294495 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0293984 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0293809 |
| PTEN | phosphatase and tensin homolog | -0.0293045 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.028974 |
| RNF43 | ring finger protein 43 | -0.0287735 |
| GNAS | GNAS complex locus | -0.0282759 |
| ABLIM1 | actin binding LIM protein 1 | -0.0282277 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0279212 |
| ARF1 | ADP-ribosylation factor 1 | -0.0277243 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0275966 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0274903 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0274798 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0269034 |
| AHNAK | AHNAK nucleoprotein | -0.0267334 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0262214 |
| WDR45B | WD repeat domain 45B | -0.0260384 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0260218 |
| VCL | vinculin | -0.0254885 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0254668 |
