| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elimusertib hydrochloride perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elimusertib hydrochloride_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.147465 |
| EFNA5 | ephrin-A5 | 0.0886259 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0796141 |
| FLNA | filamin A, alpha | 0.0770955 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0624454 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0585567 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0566349 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0560942 |
| VIM | vimentin | 0.0532227 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0513893 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.049623 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0440306 |
| LDHA | lactate dehydrogenase A | 0.0429508 |
| PLEC | plectin | 0.041908 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0374203 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.037197 |
| RPL4 | ribosomal protein L4 | 0.033777 |
| AHNAK | AHNAK nucleoprotein | 0.0322042 |
| ANO6 | anoctamin 6 | 0.0316188 |
| SMAD3 | SMAD family member 3 | 0.0312902 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0298064 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0289401 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0273891 |
| NAV1 | neuron navigator 1 | 0.0271711 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0270482 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0266717 |
| RPS4X | ribosomal protein S4, X-linked | 0.0265336 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0262748 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0259978 |
| PRKCE | protein kinase C, epsilon | 0.0245933 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0244186 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0239814 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0236109 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.023556 |
| TLN1 | talin 1 | 0.0230818 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0220452 |
| GOLGB1 | golgin B1 | 0.0209178 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0204833 |
| RPS18 | ribosomal protein S18 | 0.0197698 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0190448 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0190001 |
| RNF213 | ring finger protein 213 | 0.0189634 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0185691 |
| RIGI | RNA sensor RIG-I | 0.0183531 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0181898 |
| ATXN1 | ataxin 1 | 0.0180889 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0180401 |
| ETV6 | ets variant 6 | 0.0176721 |
| INTS6 | integrator complex subunit 6 | 0.0174001 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0172686 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0172416 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.016882 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0168485 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0167834 |
| TPM3 | tropomyosin 3 | 0.0167786 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0163259 |
| ARRDC3 | arrestin domain containing 3 | 0.0160512 |
| RPL3 | ribosomal protein L3 | 0.0156569 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0156127 |
| CANX | calnexin | 0.0155974 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0153599 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0150296 |
| RPL7 | ribosomal protein L7 | 0.0149564 |
| SP100 | SP100 nuclear antigen | 0.0148693 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0146336 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0142437 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0140026 |
| RPS2 | ribosomal protein S2 | 0.0139231 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.013912 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0138525 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0134778 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0131966 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0130947 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0130342 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0129578 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0129569 |
| VEGFA | vascular endothelial growth factor A | 0.0128913 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0128324 |
| MYOF | myoferlin | 0.0127984 |
| H1-2 | H1.2 linker histone, cluster member | 0.012623 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0124577 |
| HMGA2 | high mobility group AT-hook 2 | 0.012414 |
| EFNB2 | ephrin-B2 | 0.0123786 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0123601 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0123011 |
| AEBP2 | AE binding protein 2 | 0.0120155 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0119964 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0118937 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0118406 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0118119 |
| KLF10 | Kruppel-like factor 10 | 0.0117562 |
| FAT1 | FAT atypical cadherin 1 | 0.01171 |
| LAMB1 | laminin, beta 1 | 0.0116287 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0115372 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0113595 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0112929 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0112896 |
| FLNB | filamin B, beta | 0.0112205 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0111964 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0110927 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.18077 |
| MMP12 | matrix metallopeptidase 12 | -0.153624 |
| LSAMP | limbic system-associated membrane protein | -0.152454 |
| FTL | ferritin, light polypeptide | -0.123866 |
| RPS6 | ribosomal protein S6 | -0.0925017 |
| DTNA | dystrobrevin, alpha | -0.0923953 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0870066 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0856244 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0723509 |
| RTN4 | reticulon 4 | -0.0714997 |
| RPL35A | ribosomal protein L35a | -0.0687075 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0679026 |
| RPL37A | ribosomal protein L37a | -0.0655617 |
| RPS19 | ribosomal protein S19 | -0.0647918 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0645121 |
| ACTG1 | actin gamma 1 | -0.0644401 |
| PTMA | prothymosin, alpha | -0.0585328 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0575663 |
| EGR1 | early growth response 1 | -0.0555073 |
| ANXA2 | annexin A2 | -0.0553002 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0550639 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0540662 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0513427 |
| RPLP2 | ribosomal protein, large, P2 | -0.0510532 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0475412 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0471361 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0463391 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.046287 |
| RPLP1 | ribosomal protein, large, P1 | -0.0462511 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0457158 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0450141 |
| HAS2 | hyaluronan synthase 2 | -0.0446479 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0444641 |
| NF1 | neurofibromin 1 | -0.0426566 |
| SBF2 | SET binding factor 2 | -0.042558 |
| YBX3 | Y box binding protein 3 | -0.0423535 |
| TXNRD1 | thioredoxin reductase 1 | -0.0419118 |
| HMGA1 | high mobility group AT-hook 1 | -0.0411051 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.0409054 |
| MT2A | metallothionein 2A | -0.040358 |
| CD109 | CD109 molecule | -0.0401285 |
| SPAG9 | sperm associated antigen 9 | -0.0397838 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0397513 |
| RBM39 | RNA binding motif protein 39 | -0.0393953 |
| NUP58 | nucleoporin 58 | -0.038946 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0386589 |
| JMJD1C | jumonji domain containing 1C | -0.038505 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.037592 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0374984 |
| CDH13 | cadherin 13 | -0.0374873 |
| KYNU | kynureninase | -0.0374734 |
| RPS12 | ribosomal protein S12 | -0.0374093 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0369331 |
| RPL31 | ribosomal protein L31 | -0.0367547 |
| RPS24 | ribosomal protein S24 | -0.0364871 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0361893 |
| WDR45B | WD repeat domain 45B | -0.0359283 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0356844 |
| PTK2 | protein tyrosine kinase 2 | -0.0354506 |
| RPS3 | ribosomal protein S3 | -0.0354416 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0351158 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0347176 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0344506 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0344429 |
| NTM | neurotrimin | -0.0343214 |
| CDK17 | cyclin-dependent kinase 17 | -0.0341612 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0339253 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.033624 |
| WDR43 | WD repeat domain 43 | -0.0334047 |
| RPS13 | ribosomal protein S13 | -0.0327805 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0324881 |
| ZNF292 | zinc finger protein 292 | -0.0321913 |
| GNAS | GNAS complex locus | -0.0321199 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.031753 |
| NDRG1 | N-myc downstream regulated 1 | -0.0316653 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0314442 |
| RPS29 | ribosomal protein S29 | -0.0313203 |
| RPL37 | ribosomal protein L37 | -0.0312908 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0312846 |
| RNF145 | ring finger protein 145 | -0.0309745 |
| GOLGA4 | golgin A4 | -0.0308662 |
| RPL26 | ribosomal protein L26 | -0.0306356 |
| QKI | QKI, KH domain containing, RNA binding | -0.0305134 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0302875 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0301577 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0301542 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0300506 |
| RPS21 | ribosomal protein S21 | -0.0300429 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0300027 |
| RPS25 | ribosomal protein S25 | -0.0298425 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0298035 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0293856 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0293427 |
| RPS8 | ribosomal protein S8 | -0.0292436 |
| RPL36 | ribosomal protein L36 | -0.0291522 |
| ZNF207 | zinc finger protein 207 | -0.0291513 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0290674 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0290667 |
| SETD5 | SET domain containing 5 | -0.0288138 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0286788 |
