| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elimusertib hydrochloride perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elimusertib hydrochloride_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.233564 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0900082 |
| DSPP | dentin sialophosphoprotein | 0.0773744 |
| EXT1 | exostosin glycosyltransferase 1 | 0.076668 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0727754 |
| VEGFA | vascular endothelial growth factor A | 0.0689646 |
| PIGR | polymeric immunoglobulin receptor | 0.0530536 |
| MUC13 | mucin 13, cell surface associated | 0.0528648 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0528211 |
| MUC17 | mucin 17, cell surface associated | 0.0469307 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0428504 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.038857 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0379674 |
| SHROOM3 | shroom family member 3 | 0.0377863 |
| PDZD8 | PDZ domain containing 8 | 0.0344296 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0337745 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0333302 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0332037 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0317222 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0309576 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.028777 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0282992 |
| CALR | calreticulin | 0.0264296 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0258975 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0258695 |
| JUN | jun proto-oncogene | 0.0256941 |
| POF1B | premature ovarian failure, 1B | 0.0253041 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0245753 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | 0.024468 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0241144 |
| DUSP16 | dual specificity phosphatase 16 | 0.0240964 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0232249 |
| TMC5 | transmembrane channel-like 5 | 0.0226818 |
| RNF213 | ring finger protein 213 | 0.0225398 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.0215386 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0213121 |
| CDX2 | caudal type homeobox 2 | 0.0212398 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0211377 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0207174 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.020609 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0205262 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0202253 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0200541 |
| RHOA | ras homolog family member A | 0.0194414 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0192857 |
| EPHB2 | EPH receptor B2 | 0.0191971 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0188836 |
| HYOU1 | hypoxia up-regulated 1 | 0.0181843 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.0181386 |
| RPL3 | ribosomal protein L3 | 0.0180099 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0180038 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0173357 |
| CRY1 | cryptochrome circadian clock 1 | 0.0170801 |
| FOXP1 | forkhead box P1 | 0.016692 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0165901 |
| USP54 | ubiquitin specific peptidase 54 | 0.0165225 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0165018 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0164337 |
| B2M | beta-2-microglobulin | 0.0163858 |
| LRATD1 | LRAT domain containing 1 | 0.016265 |
| FLNA | filamin A, alpha | 0.0159898 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0158092 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0154878 |
| MT2A | metallothionein 2A | 0.0153996 |
| GOLGB1 | golgin B1 | 0.0153792 |
| HNF4G | hepatocyte nuclear factor 4, gamma | 0.0153498 |
| TMF1 | TATA element modulatory factor 1 | 0.0150087 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0150075 |
| MYO1E | myosin IE | 0.0147927 |
| RPS18 | ribosomal protein S18 | 0.0147484 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.0147071 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.0146532 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0146506 |
| ATP10B | ATPase, class V, type 10B | 0.0143984 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0143495 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0141768 |
| PRSS23 | protease, serine, 23 | 0.014109 |
| RPS2 | ribosomal protein S2 | 0.0137683 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0136415 |
| ADD3 | adducin 3 (gamma) | 0.0134678 |
| DENND4C | DENN/MADD domain containing 4C | 0.0134618 |
| NUCB2 | nucleobindin 2 | 0.0134498 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0133779 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0131648 |
| SP100 | SP100 nuclear antigen | 0.0131451 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0130617 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0129235 |
| MYO5B | myosin VB | 0.0128947 |
| TPI1 | triosephosphate isomerase 1 | 0.0128927 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0128799 |
| EFNA1 | ephrin-A1 | 0.0128581 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.0128214 |
| ZNF395 | zinc finger protein 395 | 0.0126195 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0126193 |
| GOLIM4 | golgi integral membrane protein 4 | 0.0123968 |
| HLA-E | major histocompatibility complex, class I, E | 0.012348 |
| RPS4X | ribosomal protein S4, X-linked | 0.0123443 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0123226 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0122678 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0122212 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.173238 |
| NPSR1 | neuropeptide S receptor 1 | -0.162884 |
| ANXA2 | annexin A2 | -0.152504 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.142887 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.131962 |
| TNS4 | tensin 4 | -0.124163 |
| ANTXR2 | anthrax toxin receptor 2 | -0.113493 |
| FLNB | filamin B, beta | -0.110829 |
| TMSB10 | thymosin beta 10 | -0.110151 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.105895 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.105633 |
| ITGA6 | integrin, alpha 6 | -0.0875552 |
| ONECUT3 | one cut homeobox 3 | -0.0866358 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0864886 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0842317 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0820425 |
| ASPH | aspartate beta-hydroxylase | -0.0729261 |
| VCL | vinculin | -0.0685458 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0668901 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0668144 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0657196 |
| RNF43 | ring finger protein 43 | -0.065702 |
| FAT1 | FAT atypical cadherin 1 | -0.0633085 |
| NDRG1 | N-myc downstream regulated 1 | -0.0620577 |
| CADPS | Ca++-dependent secretion activator | -0.0605033 |
| H1-0 | H1.0 linker histone | -0.0592071 |
| MED13L | mediator complex subunit 13-like | -0.0572532 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0570053 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.056337 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0562419 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0553555 |
| KRT8 | keratin 8, type II | -0.0539776 |
| GPHN | gephyrin | -0.053604 |
| FERMT1 | fermitin family member 1 | -0.0531533 |
| RPL35A | ribosomal protein L35a | -0.051955 |
| LAMA4 | laminin, alpha 4 | -0.0515779 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0500012 |
| TPM4 | tropomyosin 4 | -0.0498461 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0484857 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0483108 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0478316 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0477968 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0473074 |
| ITGB4 | integrin, beta 4 | -0.0469784 |
| RBM39 | RNA binding motif protein 39 | -0.0464909 |
| PRSS3 | protease, serine, 3 | -0.046266 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0462306 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0461203 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.046026 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0460063 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0451731 |
| RPS24 | ribosomal protein S24 | -0.0449861 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0445307 |
| EREG | epiregulin | -0.0444556 |
| EHBP1 | EH domain binding protein 1 | -0.0443501 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0443213 |
| KIF5B | kinesin family member 5B | -0.0426052 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0416244 |
| CALB1 | calbindin 1, 28kDa | -0.0410877 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0408233 |
| NFIA | nuclear factor I/A | -0.040489 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0401088 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0399718 |
| ACTG1 | actin gamma 1 | -0.0398349 |
| RREB1 | ras responsive element binding protein 1 | -0.0394955 |
| MSI2 | musashi RNA-binding protein 2 | -0.0386761 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0382984 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0380703 |
| GOLGA4 | golgin A4 | -0.0380287 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0378139 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0377158 |
| PCDHB16 | protocadherin beta 16 | -0.0376304 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0375264 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0372806 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | -0.0367573 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0363818 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0363656 |
| SMYD3 | SET and MYND domain containing 3 | -0.0362596 |
| RPLP1 | ribosomal protein, large, P1 | -0.0362412 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.035616 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.035398 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0352462 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0351316 |
| IER3 | immediate early response 3 | -0.035106 |
| WDR45B | WD repeat domain 45B | -0.0349555 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0346866 |
| RNF217 | ring finger protein 217 | -0.0346036 |
| VMP1 | vacuole membrane protein 1 | -0.0342017 |
| FAM13A | family with sequence similarity 13, member A | -0.0341841 |
| SBF2 | SET binding factor 2 | -0.0337761 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0337002 |
| NF1 | neurofibromin 1 | -0.0336022 |
| FOXO1 | forkhead box O1 | -0.0334964 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0331617 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0331296 |
| HMGA1 | high mobility group AT-hook 1 | -0.0329013 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0327275 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0325429 |
| SH3D19 | SH3 domain containing 19 | -0.0324897 |
| S100P | S100 calcium binding protein P | -0.0324402 |
