| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elimusertib hydrochloride perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elimusertib hydrochloride_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0898893 |
| LOC105378220 | macrophage receptor MARCO-like | 0.079326 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0549646 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0526794 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.041547 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0344672 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0338834 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0332147 |
| GOLGA4 | golgin A4 | 0.0309838 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0304589 |
| RPL3 | ribosomal protein L3 | 0.0281548 |
| CANX | calnexin | 0.0273429 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0266318 |
| RPS4X | ribosomal protein S4, X-linked | 0.0261051 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0260947 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0256841 |
| HLA-E | major histocompatibility complex, class I, E | 0.0253774 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0250736 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0249621 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0244173 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0240432 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0223391 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0221412 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0219112 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0205783 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.02052 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0204595 |
| ATF4 | activating transcription factor 4 | 0.0199998 |
| OPTN | optineurin | 0.019493 |
| PCBP2 | poly(rC) binding protein 2 | 0.0193803 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0192698 |
| TMF1 | TATA element modulatory factor 1 | 0.018851 |
| RPL7 | ribosomal protein L7 | 0.0186142 |
| VEGFA | vascular endothelial growth factor A | 0.0180815 |
| TXNIP | thioredoxin interacting protein | 0.0179461 |
| ARRDC3 | arrestin domain containing 3 | 0.0178075 |
| PDZD8 | PDZ domain containing 8 | 0.0176504 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0175019 |
| NDRG1 | N-myc downstream regulated 1 | 0.0164517 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0164448 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0161773 |
| SRI | sorcin | 0.016165 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0161528 |
| PGK1 | phosphoglycerate kinase 1 | 0.0161376 |
| RPL4 | ribosomal protein L4 | 0.016053 |
| CEP350 | centrosomal protein 350kDa | 0.0157459 |
| CALR | calreticulin | 0.0155689 |
| EFNA1 | ephrin-A1 | 0.0152231 |
| TBC1D15 | TBC1 domain family, member 15 | 0.015204 |
| RPS18 | ribosomal protein S18 | 0.0151497 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.014998 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0147775 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0143581 |
| MACROD2 | MACRO domain containing 2 | 0.0143267 |
| KLHL24 | kelch-like family member 24 | 0.0143184 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0142865 |
| PHF3 | PHD finger protein 3 | 0.0142092 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0141345 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0140372 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 0.0140234 |
| BRD2 | bromodomain containing 2 | 0.0139427 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0139403 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0139127 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0137809 |
| MLEC | malectin | 0.0136599 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0134808 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0134414 |
| ATF3 | activating transcription factor 3 | 0.013439 |
| FBXO32 | F-box protein 32 | 0.0134223 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0134107 |
| YME1L1 | YME1-like 1 ATPase | 0.013357 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0133405 |
| ZNF292 | zinc finger protein 292 | 0.0133256 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.0131806 |
| HYOU1 | hypoxia up-regulated 1 | 0.0131535 |
| LDHA | lactate dehydrogenase A | 0.0131039 |
| SUCO | SUN domain containing ossification factor | 0.0129312 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0127703 |
| UBC | ubiquitin C | 0.0126587 |
| RNF145 | ring finger protein 145 | 0.0126061 |
| RPL14 | ribosomal protein L14 | 0.012505 |
| MEF2C | myocyte enhancer factor 2C | 0.0123805 |
| COPA | coatomer protein complex, subunit alpha | 0.0123768 |
| TXNRD1 | thioredoxin reductase 1 | 0.0122549 |
| KIZ | kizuna centrosomal protein | 0.0122437 |
| UBN2 | ubinuclein 2 | 0.01203 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0120042 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.011936 |
| PCM1 | pericentriolar material 1 | 0.0118966 |
| CREBRF | CREB3 regulatory factor | 0.011833 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0117529 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0117487 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.011743 |
| JUN | jun proto-oncogene | 0.0117026 |
| ADAR | adenosine deaminase, RNA-specific | 0.0116012 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0115654 |
| RPL21 | ribosomal protein L21 | 0.0115074 |
| NRXN3 | neurexin 3 | 0.0114926 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0113217 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0113173 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.21786 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.192623 |
| FLNB | filamin B, beta | -0.158724 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.155756 |
| ANXA2 | annexin A2 | -0.154363 |
| MSI2 | musashi RNA-binding protein 2 | -0.118298 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.111651 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.108667 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.108597 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.104109 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0907756 |
| LMO7 | LIM domain 7 | -0.0847956 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0757304 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0754097 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0710021 |
| ITGA6 | integrin, alpha 6 | -0.0706096 |
| VCL | vinculin | -0.069443 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0674003 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0670792 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.066607 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0662956 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0645855 |
| ACTG1 | actin gamma 1 | -0.0643322 |
| LAMB3 | laminin, beta 3 | -0.060533 |
| CALB1 | calbindin 1, 28kDa | -0.0600056 |
| RPL37A | ribosomal protein L37a | -0.0596817 |
| LAMA4 | laminin, alpha 4 | -0.0586643 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0582822 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0578426 |
| EZR | ezrin | -0.0566461 |
| DENND1A | DENN/MADD domain containing 1A | -0.056614 |
| MYO1E | myosin IE | -0.0562546 |
| FRMD5 | FERM domain containing 5 | -0.0553996 |
| FBXO11 | F-box protein 11 | -0.0553789 |
| DSG3 | desmoglein 3 | -0.0543358 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0529402 |
| ACTN4 | actinin, alpha 4 | -0.0523219 |
| MYO5B | myosin VB | -0.0515876 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0510693 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.049991 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0489156 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0485344 |
| AOPEP | aminopeptidase O (putative) | -0.0478788 |
| SERINC5 | serine incorporator 5 | -0.0477593 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0477563 |
| PRSS3 | protease, serine, 3 | -0.0477475 |
| MCU | mitochondrial calcium uniporter | -0.0472167 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0453755 |
| RPS24 | ribosomal protein S24 | -0.0452372 |
| RPLP2 | ribosomal protein, large, P2 | -0.0444107 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0443246 |
| FOXO1 | forkhead box O1 | -0.0442147 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0439768 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0435855 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0431748 |
| KRT8 | keratin 8, type II | -0.0426243 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0420411 |
| FHIT | fragile histidine triad | -0.0416571 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.041474 |
| RPL35A | ribosomal protein L35a | -0.0413488 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0410415 |
| EGFR | epidermal growth factor receptor | -0.0405977 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.040509 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0398022 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0395518 |
| RBM25 | RNA binding motif protein 25 | -0.0393986 |
| RPS12 | ribosomal protein S12 | -0.039105 |
| RAD51B | RAD51 paralog B | -0.0385991 |
| SH3D19 | SH3 domain containing 19 | -0.0380359 |
| PIK3AP1 | phosphoinositide-3-kinase adaptor protein 1 | -0.0379629 |
| RPS25 | ribosomal protein S25 | -0.037761 |
| TCF12 | transcription factor 12 | -0.0377192 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0375911 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0373965 |
| DSPP | dentin sialophosphoprotein | -0.0373423 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0371095 |
| INTS6 | integrator complex subunit 6 | -0.0368452 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0365004 |
| RREB1 | ras responsive element binding protein 1 | -0.0363178 |
| CTBP2 | C-terminal binding protein 2 | -0.0362615 |
| PALLD | palladin, cytoskeletal associated protein | -0.0360916 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.036039 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0358669 |
| COBL | cordon-bleu WH2 repeat protein | -0.0357872 |
| SPON1 | spondin 1, extracellular matrix protein | -0.0357763 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.035591 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0353236 |
| RCOR1 | REST corepressor 1 | -0.0352223 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0351448 |
| NPSR1 | neuropeptide S receptor 1 | -0.0351113 |
| RPL26 | ribosomal protein L26 | -0.0346982 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0346777 |
| JMJD1C | jumonji domain containing 1C | -0.0345104 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0344413 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0342305 |
| TC2N | tandem C2 domains, nuclear | -0.0341239 |
| CUX1 | cut-like homeobox 1 | -0.0337103 |
| RPL31 | ribosomal protein L31 | -0.0332749 |
| SVIL | supervillin | -0.0332496 |
| MTAP | methylthioadenosine phosphorylase | -0.0332124 |
