| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elimusertib hydrochloride perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elimusertib hydrochloride_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A2 | collagen, type V, alpha 2 | 0.148117 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.104018 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0957514 |
| MAP7 | microtubule-associated protein 7 | 0.0571224 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0566498 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0564386 |
| PDE10A | phosphodiesterase 10A | 0.0542591 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0524831 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0521114 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0479154 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0461452 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.046082 |
| DST | dystonin | 0.0460141 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0454824 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0450821 |
| OLFML2A | olfactomedin-like 2A | 0.0449651 |
| PALLD | palladin, cytoskeletal associated protein | 0.044445 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0421546 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0416106 |
| XYLT1 | xylosyltransferase I | 0.0413638 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0392114 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0385101 |
| PCDH15 | protocadherin-related 15 | 0.0379977 |
| FLNA | filamin A, alpha | 0.0363796 |
| SMAD2 | SMAD family member 2 | 0.0352648 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0349521 |
| NFX1 | nuclear transcription factor, X-box binding 1 | 0.0348329 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0347868 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0343382 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0337422 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.033236 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0323677 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0307089 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0303056 |
| DNER | delta/notch-like EGF repeat containing | 0.029629 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0284114 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0280777 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0275614 |
| ATXN1 | ataxin 1 | 0.0275199 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0273256 |
| OXSR1 | oxidative stress responsive 1 | 0.0272285 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.0272213 |
| KRT19 | keratin 19, type I | 0.026965 |
| MYOF | myoferlin | 0.0265565 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0264414 |
| ZFHX3 | zinc finger homeobox 3 | 0.026351 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0259807 |
| ABLIM1 | actin binding LIM protein 1 | 0.025918 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0252734 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0247198 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0244246 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.024201 |
| L1CAM | L1 cell adhesion molecule | 0.024068 |
| KYNU | kynureninase | 0.0240445 |
| AUTS2 | autism susceptibility candidate 2 | 0.0237955 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0237573 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0236427 |
| CHL1 | cell adhesion molecule L1-like | 0.0232438 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0229655 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0225561 |
| CHSY3 | chondroitin sulfate synthase 3 | 0.0216671 |
| INTS6 | integrator complex subunit 6 | 0.0214814 |
| EFNA1 | ephrin-A1 | 0.0213557 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0210789 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0210656 |
| PRR5L | proline rich 5 like | 0.0201228 |
| FRY | furry homolog (Drosophila) | 0.0199248 |
| PRELID2 | PRELI domain containing 2 | 0.0197975 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0197809 |
| LSAMP | limbic system-associated membrane protein | 0.0194893 |
| TBXT | T-box transcription factor T | 0.0191404 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0189646 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | 0.0186731 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0185412 |
| RHOB | ras homolog family member B | 0.018314 |
| RHOA | ras homolog family member A | 0.0180916 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0180476 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 0.0178058 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0176255 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | 0.0173055 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0172505 |
| CLU | clusterin | 0.0170221 |
| NTN4 | netrin 4 | 0.0170026 |
| NRXN3 | neurexin 3 | 0.0169929 |
| MYO10 | myosin X | 0.0168796 |
| EPHA5 | EPH receptor A5 | 0.0166966 |
| NBEAL1 | neurobeachin-like 1 | 0.0162219 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0161858 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0161361 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0159459 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0156829 |
| HDAC4 | histone deacetylase 4 | 0.0156076 |
| EZR | ezrin | 0.0155589 |
| IRS2 | insulin receptor substrate 2 | 0.0155222 |
| EGFR | epidermal growth factor receptor | 0.015389 |
| TENM2 | teneurin transmembrane protein 2 | 0.0152223 |
| DISP1 | dispatched homolog 1 (Drosophila) | 0.0151459 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0150615 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0149352 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0149189 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EFNA5 | ephrin-A5 | -0.255268 |
| GDA | guanine deaminase | -0.148541 |
| FTL | ferritin, light polypeptide | -0.13671 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.131729 |
| NRCAM | neuronal cell adhesion molecule | -0.11561 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.110668 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.097706 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0952577 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0917763 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0912295 |
| TXNRD1 | thioredoxin reductase 1 | -0.0868074 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0864764 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0780205 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0777614 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0751209 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0748095 |
| RPL37A | ribosomal protein L37a | -0.073024 |
| CDH13 | cadherin 13 | -0.0711196 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0707256 |
| TMSB10 | thymosin beta 10 | -0.0691228 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0687832 |
| RPS24 | ribosomal protein S24 | -0.068292 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0653663 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0626907 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0619639 |
| PCBP3 | poly(rC) binding protein 3 | -0.0606096 |
| GRAMD1B | GRAM domain containing 1B | -0.0602663 |
| RPS6 | ribosomal protein S6 | -0.0598759 |
| RPL26 | ribosomal protein L26 | -0.0593308 |
| PTMA | prothymosin, alpha | -0.0585223 |
| RPS12 | ribosomal protein S12 | -0.0577934 |
| RPL35A | ribosomal protein L35a | -0.0574062 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0570217 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0555739 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0551244 |
| RPLP1 | ribosomal protein, large, P1 | -0.0548678 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0516275 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0495798 |
| RTN4 | reticulon 4 | -0.0495587 |
| RPL31 | ribosomal protein L31 | -0.0491973 |
| TNPO1 | transportin 1 | -0.0490975 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0486043 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0474735 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0454915 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0449356 |
| RPS27A | ribosomal protein S27a | -0.044152 |
| RPS19 | ribosomal protein S19 | -0.0440314 |
| RPS3 | ribosomal protein S3 | -0.0436029 |
| CTSC | cathepsin C | -0.0431138 |
| RPL12 | ribosomal protein L12 | -0.04271 |
| RPLP2 | ribosomal protein, large, P2 | -0.0424843 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0423967 |
| RPL23 | ribosomal protein L23 | -0.0423312 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0419921 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0418677 |
| RPS29 | ribosomal protein S29 | -0.0410721 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0402917 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0399523 |
| RTN1 | reticulon 1 | -0.0399238 |
| STC1 | stanniocalcin 1 | -0.039779 |
| RPL9 | ribosomal protein L9 | -0.0392342 |
| SMYD3 | SET and MYND domain containing 3 | -0.0390012 |
| RPL37 | ribosomal protein L37 | -0.03863 |
| GLIS3 | GLIS family zinc finger 3 | -0.0372401 |
| RPS8 | ribosomal protein S8 | -0.0371968 |
| RPL7A | ribosomal protein L7a | -0.0368296 |
| RPS25 | ribosomal protein S25 | -0.036602 |
| ASPH | aspartate beta-hydroxylase | -0.0363238 |
| RPL36 | ribosomal protein L36 | -0.035567 |
| RPL11 | ribosomal protein L11 | -0.035411 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0342914 |
| RBM39 | RNA binding motif protein 39 | -0.0338509 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0337999 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0332814 |
| RPL19 | ribosomal protein L19 | -0.0326005 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0324844 |
| RPL36A | ribosomal protein L36a | -0.0324753 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0324684 |
| BMERB1 | bMERB domain containing 1 | -0.032263 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0322472 |
| MCL1 | myeloid cell leukemia 1 | -0.032203 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0315708 |
| ENAH | enabled homolog (Drosophila) | -0.0315617 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.031283 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0312544 |
| COL4A6 | collagen, type IV, alpha 6 | -0.0311383 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0307669 |
| RPS14 | ribosomal protein S14 | -0.0306768 |
| GOLGA4 | golgin A4 | -0.0306381 |
| RPL34 | ribosomal protein L34 | -0.0305928 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0305782 |
| RPL13A | ribosomal protein L13a | -0.0305764 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0300358 |
| RACK1 | receptor for activated C kinase 1 | -0.0299606 |
| RPS21 | ribosomal protein S21 | -0.0296638 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0294105 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0291349 |
| SLC38A2 | solute carrier family 38, member 2 | -0.028934 |
| RPLP0 | ribosomal protein, large, P0 | -0.0287335 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0287168 |
