| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elimusertib hydrochloride perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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110 genes differentially expressed following the Elimusertib hydrochloride_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.276248 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.173909 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.137626 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.134786 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.126191 |
| SBF2 | SET binding factor 2 | 0.123009 |
| EGFR | epidermal growth factor receptor | 0.122881 |
| TSC22D2 | TSC22 domain family, member 2 | 0.119965 |
| FN1 | fibronectin 1 | 0.116043 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.114652 |
| FNDC3B | fibronectin type III domain containing 3B | 0.110274 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.10186 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0995102 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0952575 |
| HMGB2 | high mobility group box 2 | 0.0949451 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.094576 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0931349 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0874124 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0868755 |
| CALR | calreticulin | 0.0867189 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0850437 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0825585 |
| RAD21 | RAD21 homolog (S. pombe) | 0.079522 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0766645 |
| TMEM123 | transmembrane protein 123 | 0.0751487 |
| HDLBP | high density lipoprotein binding protein | 0.0725088 |
| COL1A1 | collagen, type I, alpha 1 | 0.0683426 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0657237 |
| VIM | vimentin | 0.0648999 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0619222 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0586837 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0540679 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0504153 |
| DST | dystonin | 0.0494434 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0319872 |
| RPL31 | ribosomal protein L31 | 0.0311575 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0256615 |
| NDRG1 | N-myc downstream regulated 1 | 0.0250008 |
| RPL7 | ribosomal protein L7 | 0.0237845 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0233614 |
| EFNA5 | ephrin-A5 | 0.0202209 |
| RPLP1 | ribosomal protein, large, P1 | 0.0184417 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0146539 |
| RPS10 | ribosomal protein S10 | 0.0122034 |
| RBM39 | RNA binding motif protein 39 | 0.0088511 |
| RPL11 | ribosomal protein L11 | 0.00669088 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.00644627 |
| RBM25 | RNA binding motif protein 25 | 0.00307715 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.00160939 |
| PGK1 | phosphoglycerate kinase 1 | 8.65462E-5 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.215843 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.21438 |
| MT2A | metallothionein 2A | -0.165155 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.155104 |
| RPS19 | ribosomal protein S19 | -0.131844 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.120766 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.111522 |
| IGF2 | insulin-like growth factor 2 | -0.0996944 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0972516 |
| CDH13 | cadherin 13 | -0.0945947 |
| RPL37A | ribosomal protein L37a | -0.0938274 |
| RPS8 | ribosomal protein S8 | -0.0912695 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0908385 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0852837 |
| NAV2 | neuron navigator 2 | -0.0819267 |
| MED13 | mediator complex subunit 13 | -0.0794899 |
| PTMA | prothymosin, alpha | -0.0776046 |
| RPL35A | ribosomal protein L35a | -0.0759385 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0744239 |
| RPL34 | ribosomal protein L34 | -0.0671988 |
| HMGA2 | high mobility group AT-hook 2 | -0.0660414 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0633463 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0631286 |
| SMYD3 | SET and MYND domain containing 3 | -0.0629773 |
| RPL26 | ribosomal protein L26 | -0.0606244 |
| RPL23 | ribosomal protein L23 | -0.0605123 |
| RPS25 | ribosomal protein S25 | -0.0558199 |
| COL5A1 | collagen, type V, alpha 1 | -0.0526333 |
| VCL | vinculin | -0.0520429 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0516397 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0503212 |
| B2M | beta-2-microglobulin | -0.0492936 |
| GOLGA4 | golgin A4 | -0.0470253 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0466281 |
| RPS6 | ribosomal protein S6 | -0.0452192 |
| MCL1 | myeloid cell leukemia 1 | -0.0426435 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0413088 |
| TMSB10 | thymosin beta 10 | -0.0408806 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0401383 |
| STC1 | stanniocalcin 1 | -0.0375316 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0362661 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0361082 |
| ASPH | aspartate beta-hydroxylase | -0.0358567 |
| LMO7 | LIM domain 7 | -0.034009 |
| RPL13A | ribosomal protein L13a | -0.0339626 |
| FTL | ferritin, light polypeptide | -0.0267841 |
| RPLP2 | ribosomal protein, large, P2 | -0.0260118 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0238268 |
| JMJD1C | jumonji domain containing 1C | -0.0230433 |
| PDE10A | phosphodiesterase 10A | -0.0179579 |
| LDHA | lactate dehydrogenase A | -0.017949 |
| RPS3 | ribosomal protein S3 | -0.0160823 |
| RPS12 | ribosomal protein S12 | -0.0139809 |
| MYO1E | myosin IE | -0.00942055 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.00898926 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.00767367 |
| PRRC2C | proline-rich coiled-coil 2C | -0.00514636 |
| ZNF292 | zinc finger protein 292 | -0.00343992 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00314718 |
| ERBIN | erbb2 interacting protein | -0.00193467 |
