| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elimusertib hydrochloride perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Elimusertib hydrochloride_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | 0.12808 |
| NTM | neurotrimin | 0.0876273 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0827917 |
| COL5A2 | collagen, type V, alpha 2 | 0.0754199 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0697104 |
| COL3A1 | collagen, type III, alpha 1 | 0.0672636 |
| DOCK5 | dedicator of cytokinesis 5 | 0.055612 |
| LPIN2 | lipin 2 | 0.0552821 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0533404 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.049391 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0466175 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0454959 |
| VIM | vimentin | 0.0452734 |
| FOXG1 | forkhead box G1 | 0.0439099 |
| LDHA | lactate dehydrogenase A | 0.0416429 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0406872 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0400725 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0380874 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0360574 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0354929 |
| BRD2 | bromodomain containing 2 | 0.0354813 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0352133 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0350295 |
| CALR | calreticulin | 0.0341255 |
| PCDH18 | protocadherin 18 | 0.0341161 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0340887 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0329528 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0323601 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0321478 |
| SFTPA2 | surfactant protein A2 | 0.0314889 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 0.031025 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0309281 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.030787 |
| AFAP1 | actin filament associated protein 1 | 0.0306858 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0304967 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0297225 |
| JUN | jun proto-oncogene | 0.0283547 |
| NXN | nucleoredoxin | 0.0277125 |
| CECR2 | cat eye syndrome chromosome region, candidate 2 | 0.027287 |
| LMO7 | LIM domain 7 | 0.027228 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0261556 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0260799 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0259386 |
| ERBIN | erbb2 interacting protein | 0.0255073 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0252881 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0249484 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0248953 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 0.0238351 |
| ATXN2 | ataxin 2 | 0.0233895 |
| KLHL24 | kelch-like family member 24 | 0.0233466 |
| RSF1 | remodeling and spacing factor 1 | 0.0232513 |
| ARRDC3 | arrestin domain containing 3 | 0.0230457 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0225281 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0224862 |
| GPC4 | glypican 4 | 0.022393 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0221957 |
| TBL1X | transducin (beta)-like 1X-linked | 0.022055 |
| UPP1 | uridine phosphorylase 1 | 0.0220214 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.021837 |
| RCOR1 | REST corepressor 1 | 0.0218241 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0216508 |
| OAZ1 | ornithine decarboxylase antizyme 1 | 0.0215874 |
| CEP350 | centrosomal protein 350kDa | 0.0215645 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0213783 |
| MYO10 | myosin X | 0.0213488 |
| ANO6 | anoctamin 6 | 0.0210858 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0206802 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0206625 |
| ADM | adrenomedullin | 0.0206516 |
| EGFR | epidermal growth factor receptor | 0.0206144 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0206014 |
| PCDH7 | protocadherin 7 | 0.0205697 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0202995 |
| NFIA | nuclear factor I/A | 0.0202963 |
| FAT1 | FAT atypical cadherin 1 | 0.0201657 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0201176 |
| PPL | periplakin | 0.0201107 |
| VEGFA | vascular endothelial growth factor A | 0.0196638 |
| FGF13 | fibroblast growth factor 13 | 0.0196337 |
| WWC2 | WW and C2 domain containing 2 | 0.0195564 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0195097 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0193842 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0193578 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.019251 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.0191081 |
| BBX | bobby sox homolog (Drosophila) | 0.0186945 |
| TSPAN12 | tetraspanin 12 | 0.0185895 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0185293 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0185205 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0182918 |
| SMAD6 | SMAD family member 6 | 0.018175 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0180713 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0180625 |
| USP34 | ubiquitin specific peptidase 34 | 0.0180358 |
| NCOA1 | nuclear receptor coactivator 1 | 0.0177656 |
| HYOU1 | hypoxia up-regulated 1 | 0.0174745 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0173162 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0172824 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0172769 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 0.0170646 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.152041 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.114501 |
| PEG10 | paternally expressed 10 | -0.0883075 |
| MKI67 | marker of proliferation Ki-67 | -0.0822584 |
| TMSB10 | thymosin beta 10 | -0.0796647 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0791752 |
| CENPF | centromere protein F, 350/400kDa | -0.0780166 |
| PTMA | prothymosin, alpha | -0.0730503 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0722871 |
| ZNF292 | zinc finger protein 292 | -0.0678086 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0676557 |
| TENM2 | teneurin transmembrane protein 2 | -0.0632961 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0624799 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0623072 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0608788 |
| RPS12 | ribosomal protein S12 | -0.0585838 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0565005 |
| CENPE | centromere protein E, 312kDa | -0.0553656 |
| EMP1 | epithelial membrane protein 1 | -0.0519685 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0514224 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0508334 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0495737 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0491259 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0476141 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0475573 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0472498 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0459141 |
| RASAL2 | RAS protein activator like 2 | -0.0457764 |
| SYT1 | synaptotagmin I | -0.0438664 |
| GPC3 | glypican 3 | -0.043749 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0431217 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0430582 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0429998 |
| PFN1 | profilin 1 | -0.0423946 |
| TPX2 | TPX2, microtubule-associated | -0.0421415 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0409985 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0406449 |
| PHIP | pleckstrin homology domain interacting protein | -0.0405812 |
| TEX11 | testis expressed 11 | -0.0397143 |
| RPL37A | ribosomal protein L37a | -0.0395814 |
| MATR3 | matrin 3 | -0.0394949 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.039157 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0388638 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0386452 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0377207 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0359851 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0357793 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0357368 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0356307 |
| ITGAV | integrin, alpha V | -0.0347791 |
| CDC73 | cell division cycle 73 | -0.0343654 |
| DEK | DEK proto-oncogene | -0.034188 |
| CAVIN1 | caveolae associated protein 1 | -0.0340807 |
| RBM39 | RNA binding motif protein 39 | -0.0339949 |
| GNAS | GNAS complex locus | -0.0336791 |
| POTEF | POTE ankyrin domain family, member F | -0.033678 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0330263 |
| FAM168B | family with sequence similarity 168, member B | -0.0329551 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | -0.0326828 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0325213 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0324973 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0319104 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0316892 |
| SRP54 | signal recognition particle 54kDa | -0.0316244 |
| SPAG9 | sperm associated antigen 9 | -0.0313653 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0312705 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0312563 |
| RPL35A | ribosomal protein L35a | -0.0310597 |
| LYST | lysosomal trafficking regulator | -0.0309749 |
| WDR43 | WD repeat domain 43 | -0.0308519 |
| FAM171B | family with sequence similarity 171, member B | -0.0307256 |
| CDC27 | cell division cycle 27 | -0.0303744 |
| KIF4A | kinesin family member 4A | -0.0303054 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0301772 |
| RPS24 | ribosomal protein S24 | -0.0301522 |
| NCKAP1 | NCK-associated protein 1 | -0.0300793 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0300599 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0298806 |
| NOP58 | NOP58 ribonucleoprotein | -0.0297345 |
| CPA6 | carboxypeptidase A6 | -0.0294446 |
| SGO2 | shugoshin 2 | -0.0294001 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0293705 |
| QKI | QKI, KH domain containing, RNA binding | -0.0291897 |
| RPS16 | ribosomal protein S16 | -0.0290551 |
| FIGN | fidgetin | -0.0289879 |
| FBXO11 | F-box protein 11 | -0.0289783 |
| METAP2 | methionyl aminopeptidase 2 | -0.0289572 |
| RPL31 | ribosomal protein L31 | -0.0289431 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0289267 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.0288558 |
| ACTG1 | actin gamma 1 | -0.0287054 |
| RAD51B | RAD51 paralog B | -0.0286945 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0284213 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.028411 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0282126 |
| AHNAK | AHNAK nucleoprotein | -0.0282085 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0278391 |
| RHEB | Ras homolog enriched in brain | -0.0274709 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0273905 |
| ABI2 | abl-interactor 2 | -0.0273264 |
