| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elimusertib hydrochloride perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Elimusertib hydrochloride_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.103419 |
| RNF213 | ring finger protein 213 | 0.102032 |
| INTS6 | integrator complex subunit 6 | 0.0871081 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0789172 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0752013 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0656529 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0610931 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0595024 |
| LMO7 | LIM domain 7 | 0.0586944 |
| MYO1E | myosin IE | 0.0584591 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0569621 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0567555 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0550738 |
| MX1 | MX dynamin-like GTPase 1 | 0.0540589 |
| VEGFA | vascular endothelial growth factor A | 0.0535469 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0530223 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0515242 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0509503 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0500302 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0475791 |
| C3 | complement component 3 | 0.0465901 |
| DSPP | dentin sialophosphoprotein | 0.0461373 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0460904 |
| SP100 | SP100 nuclear antigen | 0.0458856 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0452642 |
| KRT19 | keratin 19, type I | 0.0450874 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0440725 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0440669 |
| MX2 | MX dynamin-like GTPase 2 | 0.0420602 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0419833 |
| FAM107B | family with sequence similarity 107, member B | 0.0417833 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0393239 |
| G0S2 | G0/G1 switch 2 | 0.0390882 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0389942 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0386894 |
| KRT18 | keratin 18, type I | 0.0375104 |
| PLSCR1 | phospholipid scramblase 1 | 0.0370059 |
| RIGI | RNA sensor RIG-I | 0.0367052 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0365687 |
| CANX | calnexin | 0.0362983 |
| FN1 | fibronectin 1 | 0.0360767 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.034973 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0344303 |
| FLNA | filamin A, alpha | 0.0343694 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0339341 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0338228 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0332302 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0328454 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.032565 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0323421 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0322722 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0322127 |
| SVIL | supervillin | 0.0313605 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0312165 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0310528 |
| SIK3 | SIK family kinase 3 | 0.0310292 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0308794 |
| BRD2 | bromodomain containing 2 | 0.0308318 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0307588 |
| GOLGB1 | golgin B1 | 0.0305163 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0305095 |
| HDAC9 | histone deacetylase 9 | 0.0303927 |
| TLE4 | transducin-like enhancer of split 4 | 0.0300623 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.029916 |
| TGFB2 | transforming growth factor, beta 2 | 0.0296502 |
| IFI44L | interferon-induced protein 44-like | 0.0296347 |
| MUC16 | mucin 16, cell surface associated | 0.029563 |
| TJP1 | tight junction protein 1 | 0.0294904 |
| WWC1 | WW and C2 domain containing 1 | 0.0292444 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0292182 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0289101 |
| PSEN1 | presenilin 1 | 0.0285469 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0284804 |
| PLEC | plectin | 0.0284505 |
| ASS1 | argininosuccinate synthase 1 | 0.0283635 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0282435 |
| SEPTIN9 | septin 9 | 0.0282045 |
| H2AC6 | H2A clustered histone 6 | 0.0274347 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | 0.0272778 |
| CLDN1 | claudin 1 | 0.0271331 |
| CFB | complement factor B | 0.027128 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0270435 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.027019 |
| SYT14 | synaptotagmin XIV | 0.0270087 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0266474 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.026134 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.02569 |
| KYNU | kynureninase | 0.0249699 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0248897 |
| STC2 | stanniocalcin 2 | 0.0246393 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0245611 |
| ERBIN | erbb2 interacting protein | 0.0240662 |
| CTBP2 | C-terminal binding protein 2 | 0.0238036 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | 0.0230667 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0228583 |
| SQSTM1 | sequestosome 1 | 0.022675 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0226355 |
| FMNL2 | formin-like 2 | 0.0224073 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0222133 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0220729 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.290093 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.11438 |
| FAM3C | family with sequence similarity 3, member C | -0.104691 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.101682 |
| ANXA2 | annexin A2 | -0.0882636 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0850151 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0796318 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0787163 |
| LAMA4 | laminin, alpha 4 | -0.0730119 |
| TSC22D2 | TSC22 domain family, member 2 | -0.071933 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0710311 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0700953 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0687378 |
| EMP1 | epithelial membrane protein 1 | -0.0657994 |
| RUNX1 | runt-related transcription factor 1 | -0.0656528 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0654172 |
| ANLN | anillin, actin binding protein | -0.064495 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0616442 |
| ECT2 | epithelial cell transforming 2 | -0.0601089 |
| NDRG1 | N-myc downstream regulated 1 | -0.0600191 |
| AHNAK | AHNAK nucleoprotein | -0.0595868 |
| RPL35A | ribosomal protein L35a | -0.059121 |
| DIAPH3 | diaphanous-related formin 3 | -0.058272 |
| MKI67 | marker of proliferation Ki-67 | -0.0578265 |
| HMGA1 | high mobility group AT-hook 1 | -0.0567999 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0554474 |
| TMSB10 | thymosin beta 10 | -0.0553167 |
| DSG2 | desmoglein 2 | -0.0549477 |
| TMEM123 | transmembrane protein 123 | -0.0544265 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0542546 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0540437 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0531899 |
| RTN4 | reticulon 4 | -0.052915 |
| RLF | rearranged L-myc fusion | -0.0488308 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0472849 |
| LDHA | lactate dehydrogenase A | -0.0472824 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0472364 |
| CDCP1 | CUB domain containing protein 1 | -0.0463618 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0457451 |
| RBM39 | RNA binding motif protein 39 | -0.0453117 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0446176 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0440162 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0423126 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0412652 |
| DEK | DEK proto-oncogene | -0.0411199 |
| EGR1 | early growth response 1 | -0.0406937 |
| WDR45B | WD repeat domain 45B | -0.040396 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -0.0401405 |
| PTMA | prothymosin, alpha | -0.0395357 |
| RPS24 | ribosomal protein S24 | -0.0393674 |
| SMYD3 | SET and MYND domain containing 3 | -0.0392703 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0390319 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.038992 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0389243 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0388998 |
| KRT8 | keratin 8, type II | -0.0388814 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0383585 |
| NF1 | neurofibromin 1 | -0.0383052 |
| TXNRD1 | thioredoxin reductase 1 | -0.0382391 |
| TOP1 | topoisomerase (DNA) I | -0.0381697 |
| OGA | O-GlcNAcase | -0.0377021 |
| GOLGA4 | golgin A4 | -0.0376972 |
| FOSL1 | FOS-like antigen 1 | -0.0375653 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0366122 |
| RPS25 | ribosomal protein S25 | -0.0360511 |
| RPS19 | ribosomal protein S19 | -0.0360016 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0356298 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0355931 |
| CENPF | centromere protein F, 350/400kDa | -0.0353911 |
| EHF | ets homologous factor | -0.0352288 |
| ASPH | aspartate beta-hydroxylase | -0.0349249 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0347283 |
| PTK2 | protein tyrosine kinase 2 | -0.0347111 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.034531 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0341501 |
| RPS21 | ribosomal protein S21 | -0.034136 |
| ATP11B | ATPase, class VI, type 11B | -0.0339748 |
| RASA2 | RAS p21 protein activator 2 | -0.0338979 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0335956 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0333792 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0333152 |
| RPL37A | ribosomal protein L37a | -0.0329933 |
| EPCAM | epithelial cell adhesion molecule | -0.032417 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0322994 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0321966 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0319494 |
| S100A6 | S100 calcium binding protein A6 | -0.0319347 |
| PGK1 | phosphoglycerate kinase 1 | -0.0318313 |
| AFAP1 | actin filament associated protein 1 | -0.0317941 |
| ITGA6 | integrin, alpha 6 | -0.0317882 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0316053 |
| CD44 | CD44 molecule (Indian blood group) | -0.0314992 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0314589 |
| NEK7 | NIMA-related kinase 7 | -0.0311811 |
| TFG | TRK-fused gene | -0.0307872 |
| KIF5B | kinesin family member 5B | -0.0307649 |
| SBF2 | SET binding factor 2 | -0.0305617 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0303943 |
| OSMR | oncostatin M receptor | -0.0303631 |
| HLA-C | major histocompatibility complex, class I, C | -0.030286 |
