| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elimusertib hydrochloride perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elimusertib hydrochloride_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD6 | FERM domain containing 6 | 0.148832 |
| HDAC9 | histone deacetylase 9 | 0.10329 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0753516 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0660737 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0612102 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0607027 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0560368 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0488336 |
| FLNA | filamin A, alpha | 0.0467854 |
| SP100 | SP100 nuclear antigen | 0.0444962 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0394221 |
| CALD1 | caldesmon 1 | 0.0391893 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0386744 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.038016 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0371747 |
| RAD51B | RAD51 paralog B | 0.0358581 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0335049 |
| FNIP1 | folliculin interacting protein 1 | 0.0316921 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0311049 |
| HMGA2 | high mobility group AT-hook 2 | 0.0300336 |
| CANX | calnexin | 0.0293294 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.028955 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0286615 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0286548 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0282755 |
| INTS6 | integrator complex subunit 6 | 0.0280575 |
| RNF213 | ring finger protein 213 | 0.0276911 |
| SMAD3 | SMAD family member 3 | 0.0270233 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0263772 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0263387 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0260581 |
| CMIP | c-Maf inducing protein | 0.0259341 |
| MCL1 | myeloid cell leukemia 1 | 0.0256086 |
| RASAL2 | RAS protein activator like 2 | 0.0242332 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0230326 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0219401 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0218752 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.021664 |
| SQSTM1 | sequestosome 1 | 0.0214788 |
| GOLGB1 | golgin B1 | 0.0210038 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0209127 |
| ADAR | adenosine deaminase, RNA-specific | 0.0209065 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0209033 |
| RPS4X | ribosomal protein S4, X-linked | 0.0206059 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0204003 |
| TRIM14 | tripartite motif containing 14 | 0.0200638 |
| SQLE | squalene epoxidase | 0.0199142 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.019788 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0191773 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0189514 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0186497 |
| UTRN | utrophin | 0.0185857 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.018565 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0185463 |
| SCFD1 | sec1 family domain containing 1 | 0.0183505 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0183454 |
| UBAP2 | ubiquitin associated protein 2 | 0.0183054 |
| BPTF | bromodomain PHD finger transcription factor | 0.0182334 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0182079 |
| PRELID2 | PRELI domain containing 2 | 0.0182078 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0181861 |
| FAM120A | family with sequence similarity 120A | 0.0179982 |
| CUX1 | cut-like homeobox 1 | 0.0178822 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0178571 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0176629 |
| HYOU1 | hypoxia up-regulated 1 | 0.0175991 |
| CEP250 | centrosomal protein 250kDa | 0.0175177 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0172658 |
| RPL3 | ribosomal protein L3 | 0.0171543 |
| ATF4 | activating transcription factor 4 | 0.0169453 |
| ANK2 | ankyrin 2, neuronal | 0.0167721 |
| ANO6 | anoctamin 6 | 0.0166941 |
| CEP350 | centrosomal protein 350kDa | 0.0164133 |
| UBN2 | ubinuclein 2 | 0.0159038 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0158825 |
| ZNF146 | zinc finger protein 146 | 0.0155471 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.01544 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0154238 |
| GOLGA2 | golgin A2 | 0.015305 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.015292 |
| AEBP2 | AE binding protein 2 | 0.0148943 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0147666 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0147554 |
| NRDC | nardilysin convertase | 0.0147493 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0146728 |
| PHF3 | PHD finger protein 3 | 0.0146617 |
| GSE1 | Gse1 coiled-coil protein | 0.0146584 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0146093 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0145086 |
| BRD2 | bromodomain containing 2 | 0.0144622 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0143619 |
| NCOR2 | nuclear receptor corepressor 2 | 0.014306 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0142972 |
| GTPBP2 | GTP binding protein 2 | 0.0142591 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0141572 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0140572 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0139981 |
| EXOC4 | exocyst complex component 4 | 0.0138932 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.0138783 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0137938 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAV3 | neuron navigator 3 | -0.171217 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.14936 |
| FTL | ferritin, light polypeptide | -0.107279 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.105163 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.09388 |
| STC1 | stanniocalcin 1 | -0.0911195 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0867725 |
| MT2A | metallothionein 2A | -0.0783935 |
| RPS6 | ribosomal protein S6 | -0.0783254 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0761396 |
| TXNRD1 | thioredoxin reductase 1 | -0.0755423 |
| S100A2 | S100 calcium binding protein A2 | -0.073928 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0724976 |
| ZNF438 | zinc finger protein 438 | -0.0709028 |
| RPLP1 | ribosomal protein, large, P1 | -0.0656726 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0656684 |
| LAMB3 | laminin, beta 3 | -0.065042 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0640007 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0613688 |
| RPL37A | ribosomal protein L37a | -0.0596839 |
| RPLP2 | ribosomal protein, large, P2 | -0.0586801 |
| ACTG1 | actin gamma 1 | -0.0547591 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0542421 |
| RPL35A | ribosomal protein L35a | -0.052917 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0527398 |
| RPL12 | ribosomal protein L12 | -0.0527369 |
| PTK2 | protein tyrosine kinase 2 | -0.0512956 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0511789 |
| RPS12 | ribosomal protein S12 | -0.0509897 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0497207 |
| RASA2 | RAS p21 protein activator 2 | -0.0495623 |
| HMGA1 | high mobility group AT-hook 1 | -0.0489143 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0486251 |
| RPS24 | ribosomal protein S24 | -0.0474169 |
| USP3 | ubiquitin specific peptidase 3 | -0.0472725 |
| RPL11 | ribosomal protein L11 | -0.0455748 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0455239 |
| RPS19 | ribosomal protein S19 | -0.0444669 |
| FRMD4A | FERM domain containing 4A | -0.0440467 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0427545 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0423758 |
| RPL36 | ribosomal protein L36 | -0.0415503 |
| RTN4 | reticulon 4 | -0.0399725 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.039819 |
| RPS29 | ribosomal protein S29 | -0.0394545 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.039298 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.039169 |
| RPL30 | ribosomal protein L30 | -0.0389585 |
| RPL9 | ribosomal protein L9 | -0.0389018 |
| RPL26 | ribosomal protein L26 | -0.0386793 |
| RPL7A | ribosomal protein L7a | -0.0376018 |
| RBM39 | RNA binding motif protein 39 | -0.0373992 |
| RPS21 | ribosomal protein S21 | -0.035692 |
| RPS3 | ribosomal protein S3 | -0.0355599 |
| OLA1 | Obg-like ATPase 1 | -0.0351128 |
| ZNF292 | zinc finger protein 292 | -0.0345437 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0344991 |
| NUP58 | nucleoporin 58 | -0.0344016 |
| RPL35 | ribosomal protein L35 | -0.0343653 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0342861 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0342068 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0341941 |
| RPL23 | ribosomal protein L23 | -0.034129 |
| NF1 | neurofibromin 1 | -0.0336181 |
| WDR45B | WD repeat domain 45B | -0.0333642 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0331537 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0331433 |
| ANXA5 | annexin A5 | -0.0331321 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0328585 |
| TEX10 | testis expressed 10 | -0.0328271 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0326018 |
| RLF | rearranged L-myc fusion | -0.0323769 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0323037 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0322842 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.031824 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0318033 |
| SRPK2 | SRSF protein kinase 2 | -0.0317268 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0316492 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0314471 |
| RPS27A | ribosomal protein S27a | -0.0313916 |
| RPL34 | ribosomal protein L34 | -0.0312808 |
| TMEM156 | transmembrane protein 156 | -0.0311881 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0306788 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0306688 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0302856 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0302164 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0300047 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0298795 |
| STK4 | serine/threonine kinase 4 | -0.0298391 |
| RPL13A | ribosomal protein L13a | -0.0296768 |
| RBM25 | RNA binding motif protein 25 | -0.0295046 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0295002 |
| TPD52 | tumor protein D52 | -0.0294635 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0294185 |
| RPS8 | ribosomal protein S8 | -0.0292974 |
| PFN1 | profilin 1 | -0.0289724 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0287731 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0286171 |
| CDK17 | cyclin-dependent kinase 17 | -0.0284989 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0283283 |
