| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elimusertib hydrochloride perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Elimusertib hydrochloride_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HDAC9 | histone deacetylase 9 | 0.12198 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0946447 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0916961 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0746565 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0741259 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0704525 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0642217 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0609162 |
| ZNF608 | zinc finger protein 608 | 0.0461966 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0460488 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0395018 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0378229 |
| JUN | jun proto-oncogene | 0.0349276 |
| RHOA | ras homolog family member A | 0.0338467 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0328596 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0313251 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0303088 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0296353 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.029222 |
| RPL3 | ribosomal protein L3 | 0.029117 |
| YTHDC1 | YTH domain containing 1 | 0.0254249 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0249696 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0244274 |
| ANXA1 | annexin A1 | 0.0241444 |
| APP | amyloid beta (A4) precursor protein | 0.0232889 |
| PDGFC | platelet derived growth factor C | 0.0232788 |
| YAP1 | Yes-associated protein 1 | 0.0231922 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0225125 |
| DAPK3 | death-associated protein kinase 3 | 0.0224754 |
| VIM | vimentin | 0.022114 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0216477 |
| DUSP16 | dual specificity phosphatase 16 | 0.0215265 |
| CEP250 | centrosomal protein 250kDa | 0.0214999 |
| EZR | ezrin | 0.0213881 |
| YME1L1 | YME1-like 1 ATPase | 0.0213614 |
| SEPTIN11 | septin 11 | 0.0212539 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0211911 |
| PCBP2 | poly(rC) binding protein 2 | 0.020398 |
| RPS4X | ribosomal protein S4, X-linked | 0.020259 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0196642 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0196641 |
| KIF1B | kinesin family member 1B | 0.0192409 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0190208 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0189586 |
| VEGFA | vascular endothelial growth factor A | 0.0187484 |
| TUFT1 | tuftelin 1 | 0.018529 |
| FN1 | fibronectin 1 | 0.0185047 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0179839 |
| TXNRD1 | thioredoxin reductase 1 | 0.0179549 |
| PRRC2C | proline-rich coiled-coil 2C | 0.017808 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0176545 |
| FLNA | filamin A, alpha | 0.0176452 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0176309 |
| MACROD2 | MACRO domain containing 2 | 0.0176004 |
| PLPP3 | phospholipid phosphatase 3 | 0.0174763 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0174643 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.017279 |
| OGA | O-GlcNAcase | 0.017193 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0171702 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.0170064 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0169973 |
| RPL14 | ribosomal protein L14 | 0.0169903 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide | 0.0169516 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0169423 |
| PLCE1 | phospholipase C, epsilon 1 | 0.0168881 |
| AMOTL2 | angiomotin like 2 | 0.0167149 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0166326 |
| CREBRF | CREB3 regulatory factor | 0.0165683 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0165103 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0163722 |
| DIAPH1 | diaphanous-related formin 1 | 0.0163025 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.0162316 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0162175 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.016148 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0160863 |
| RPL7 | ribosomal protein L7 | 0.0158976 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0158003 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0157999 |
| PLXNA1 | plexin A1 | 0.0157682 |
| MCL1 | myeloid cell leukemia 1 | 0.0156385 |
| TRERF1 | transcriptional regulating factor 1 | 0.0155471 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0154817 |
| KLF6 | Kruppel-like factor 6 | 0.0148016 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0147805 |
| SMAD3 | SMAD family member 3 | 0.0147661 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0147572 |
| CLU | clusterin | 0.0147484 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0146575 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0144888 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0144875 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0143811 |
| FAT1 | FAT atypical cadherin 1 | 0.01438 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0142513 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0142021 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0141823 |
| GATA6 | GATA binding protein 6 | 0.0141713 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.014158 |
| RIOK3 | RIO kinase 3 | 0.0140741 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0140644 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0139302 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.21738 |
| PTMA | prothymosin, alpha | -0.189819 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.165017 |
| VCL | vinculin | -0.129719 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.121483 |
| BMP10 | bone morphogenetic protein 10 | -0.115448 |
| PKM | pyruvate kinase, muscle | -0.11183 |
| NBEA | neurobeachin | -0.0982463 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0930918 |
| GLI3 | GLI family zinc finger 3 | -0.092921 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0926233 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0813437 |
| FOXP1 | forkhead box P1 | -0.0764146 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.07592 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0756863 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0746605 |
| ECT2 | epithelial cell transforming 2 | -0.0731682 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0670156 |
| CCND1 | cyclin D1 | -0.0631474 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0617434 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0611661 |
| RPL35A | ribosomal protein L35a | -0.0607255 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0599142 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0597689 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0595448 |
| FLNB | filamin B, beta | -0.0593824 |
| MKI67 | marker of proliferation Ki-67 | -0.0578318 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0576231 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0571334 |
| BMP2K | BMP2 inducible kinase | -0.0559748 |
| AHNAK | AHNAK nucleoprotein | -0.053781 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0537773 |
| ACTG1 | actin gamma 1 | -0.0534487 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0532643 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0512834 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0507345 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0501472 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0499253 |
| NFIA | nuclear factor I/A | -0.0487995 |
| NAV2 | neuron navigator 2 | -0.04843 |
| PRELID2 | PRELI domain containing 2 | -0.0481834 |
| LOXL3 | lysyl oxidase-like 3 | -0.047276 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0471453 |
| RPS6 | ribosomal protein S6 | -0.0464724 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0453717 |
| HJURP | Holliday junction recognition protein | -0.0448576 |
| S100A6 | S100 calcium binding protein A6 | -0.0427476 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0425098 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0419508 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0416129 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0415619 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0407035 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0406717 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0401662 |
| GPHN | gephyrin | -0.0398251 |
| ENO1 | enolase 1, (alpha) | -0.039249 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0386867 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0386224 |
| CENPF | centromere protein F, 350/400kDa | -0.0380599 |
| NEBL | nebulette | -0.037925 |
| RPL31 | ribosomal protein L31 | -0.0368074 |
| RPS24 | ribosomal protein S24 | -0.036575 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0362976 |
| RPL34 | ribosomal protein L34 | -0.0362461 |
| PYGB | phosphorylase, glycogen; brain | -0.0353171 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0350818 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0349543 |
| PFN1 | profilin 1 | -0.0349276 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0346409 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0344065 |
| SMYD3 | SET and MYND domain containing 3 | -0.0332085 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0322227 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0321587 |
| TMSB4X | thymosin beta 4, X-linked | -0.0317235 |
| DENND1A | DENN/MADD domain containing 1A | -0.031486 |
| FHIT | fragile histidine triad | -0.0313559 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0304261 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0303486 |
| RPL5 | ribosomal protein L5 | -0.0303162 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | -0.0303041 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0300522 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0298356 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0296003 |
| RPLP2 | ribosomal protein, large, P2 | -0.0295974 |
| MYO5C | myosin VC | -0.0294809 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0294658 |
| NF1 | neurofibromin 1 | -0.0293737 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0292518 |
| RPLP1 | ribosomal protein, large, P1 | -0.0291975 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0288684 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0287657 |
| RPL9 | ribosomal protein L9 | -0.0280906 |
| USP34 | ubiquitin specific peptidase 34 | -0.0279775 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0279011 |
| ITGA10 | integrin, alpha 10 | -0.027788 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0276177 |
| TPX2 | TPX2, microtubule-associated | -0.0275354 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0271989 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0267836 |
| CENPE | centromere protein E, 312kDa | -0.0264426 |
