| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elimusertib hydrochloride perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Elimusertib hydrochloride_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.172659 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.163628 |
| HDAC9 | histone deacetylase 9 | 0.100657 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0884596 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0780035 |
| RNF213 | ring finger protein 213 | 0.0737901 |
| FLNA | filamin A, alpha | 0.0726448 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0572857 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0522809 |
| LDHA | lactate dehydrogenase A | 0.0510196 |
| VEGFA | vascular endothelial growth factor A | 0.0491095 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0490084 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.048674 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0464595 |
| HLA-E | major histocompatibility complex, class I, E | 0.0447255 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0445208 |
| MX1 | MX dynamin-like GTPase 1 | 0.0439082 |
| C3 | complement component 3 | 0.0425877 |
| SMAD3 | SMAD family member 3 | 0.0415115 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.0414124 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0380239 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0379801 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0378506 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0378127 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0371113 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0358207 |
| RIGI | RNA sensor RIG-I | 0.0357895 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.034948 |
| CEP250 | centrosomal protein 250kDa | 0.0337903 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0321505 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0317368 |
| KYNU | kynureninase | 0.0312535 |
| OPTN | optineurin | 0.03032 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | 0.0294415 |
| SP100 | SP100 nuclear antigen | 0.02782 |
| CFB | complement factor B | 0.0276485 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0275571 |
| RPS4X | ribosomal protein S4, X-linked | 0.0264381 |
| FN1 | fibronectin 1 | 0.0254665 |
| PLIN2 | perilipin 2 | 0.0254545 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0248026 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0245198 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0245106 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0229964 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0228447 |
| BRD2 | bromodomain containing 2 | 0.022296 |
| SCGB1D1 | secretoglobin, family 1D, member 1 | 0.0215305 |
| ATXN1 | ataxin 1 | 0.0213522 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0208877 |
| INTS6 | integrator complex subunit 6 | 0.0205724 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0204303 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0200954 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0198304 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0198083 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0194836 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.0193975 |
| BICC1 | BicC family RNA binding protein 1 | 0.0193765 |
| SEPTIN9 | septin 9 | 0.0193445 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0191944 |
| TRIM22 | tripartite motif containing 22 | 0.0188552 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0184167 |
| APOL1 | apolipoprotein L, 1 | 0.0183553 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0181934 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0180122 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0179858 |
| SQSTM1 | sequestosome 1 | 0.0179128 |
| CANX | calnexin | 0.0178648 |
| STC2 | stanniocalcin 2 | 0.0176209 |
| TLE4 | transducin-like enhancer of split 4 | 0.0175333 |
| PLEC | plectin | 0.0175326 |
| ZNF608 | zinc finger protein 608 | 0.0174323 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0173881 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0170104 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0169878 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0169116 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0165097 |
| PLSCR1 | phospholipid scramblase 1 | 0.0163175 |
| ATF4 | activating transcription factor 4 | 0.0160382 |
| GOLGB1 | golgin B1 | 0.0160304 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0160175 |
| GPR176 | G protein-coupled receptor 176 | 0.0158844 |
| SAMHD1 | SAM domain and HD domain 1 | 0.0158655 |
| ARRDC3 | arrestin domain containing 3 | 0.0156034 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0155657 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0155628 |
| RPL3 | ribosomal protein L3 | 0.0154261 |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 | 0.0153348 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.015298 |
| RPS18 | ribosomal protein S18 | 0.0152195 |
| FLNB | filamin B, beta | 0.0150961 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0150923 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0150617 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0149223 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0148122 |
| RASEF | RAS and EF-hand domain containing | 0.0147289 |
| DSPP | dentin sialophosphoprotein | 0.0145775 |
| TGM2 | transglutaminase 2 | 0.0145031 |
| IFI44L | interferon-induced protein 44-like | 0.01446 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.014449 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.0142769 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.170684 |
| IER3 | immediate early response 3 | -0.138381 |
| CD44 | CD44 molecule (Indian blood group) | -0.116615 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.113476 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.11304 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0974775 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0964571 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0927593 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0908566 |
| FTL | ferritin, light polypeptide | -0.0797346 |
| GLIS3 | GLIS family zinc finger 3 | -0.078903 |
| HLA-B | major histocompatibility complex, class I, B | -0.0757302 |
| TMSB10 | thymosin beta 10 | -0.0749267 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0710623 |
| RPS6 | ribosomal protein S6 | -0.0682948 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0679597 |
| FRMD4A | FERM domain containing 4A | -0.0678722 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0678607 |
| EGR1 | early growth response 1 | -0.0650026 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0605932 |
| CDH13 | cadherin 13 | -0.0604117 |
| RPS24 | ribosomal protein S24 | -0.0598907 |
| GOLGA4 | golgin A4 | -0.0593676 |
| ZNF292 | zinc finger protein 292 | -0.0584304 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0578287 |
| PTMA | prothymosin, alpha | -0.0564318 |
| HMGA2 | high mobility group AT-hook 2 | -0.0554548 |
| RPL35A | ribosomal protein L35a | -0.0541494 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0539621 |
| PGK1 | phosphoglycerate kinase 1 | -0.0539588 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0538171 |
| STC1 | stanniocalcin 1 | -0.0536467 |
| ATP13A3 | ATPase type 13A3 | -0.0527118 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0526329 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.052631 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0523215 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.052138 |
| RBM39 | RNA binding motif protein 39 | -0.050351 |
| GNAS | GNAS complex locus | -0.0501406 |
| VCAN | versican | -0.050133 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0498881 |
| RTN4 | reticulon 4 | -0.049826 |
| PDE10A | phosphodiesterase 10A | -0.0491676 |
| MT2A | metallothionein 2A | -0.0485218 |
| NDRG1 | N-myc downstream regulated 1 | -0.0477978 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0466828 |
| COL1A1 | collagen, type I, alpha 1 | -0.0465662 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0447591 |
| HMGA1 | high mobility group AT-hook 1 | -0.0442534 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0420081 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0419127 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.040894 |
| ACTG1 | actin gamma 1 | -0.0407651 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0405651 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0402372 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0401267 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0397908 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0397502 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0393954 |
| RPS21 | ribosomal protein S21 | -0.0393876 |
| RAI14 | retinoic acid induced 14 | -0.0391013 |
| SNX9 | sorting nexin 9 | -0.0390011 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0380579 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0379363 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0379118 |
| ERBIN | erbb2 interacting protein | -0.0377883 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0372103 |
| QKI | QKI, KH domain containing, RNA binding | -0.0362086 |
| RPS8 | ribosomal protein S8 | -0.0353251 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0352606 |
| OGA | O-GlcNAcase | -0.0350526 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0346098 |
| FBXO11 | F-box protein 11 | -0.0345338 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0342106 |
| NAV1 | neuron navigator 1 | -0.0340958 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0339617 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0336541 |
| SEPTIN7 | septin 7 | -0.033543 |
| RPLP0 | ribosomal protein, large, P0 | -0.0334854 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0333802 |
| DEK | DEK proto-oncogene | -0.0329658 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0328857 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0328191 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0327628 |
| SPAG9 | sperm associated antigen 9 | -0.0327399 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0324382 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0323447 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0322923 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0322881 |
| RPL32 | ribosomal protein L32 | -0.0320701 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.032023 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0313596 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0308835 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0305197 |
| WDR45B | WD repeat domain 45B | -0.030477 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0303866 |
| ANXA2 | annexin A2 | -0.02993 |
| CLMP | CXADR-like membrane protein | -0.029857 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.029631 |
| THOC2 | THO complex 2 | -0.0293824 |
