| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elimusertib hydrochloride perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elimusertib hydrochloride_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RAD51B | RAD51 paralog B | 0.0727384 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0710427 |
| ATXN1 | ataxin 1 | 0.053319 |
| EGFR | epidermal growth factor receptor | 0.0465199 |
| AXIN2 | axin 2 | 0.0425454 |
| FAT1 | FAT atypical cadherin 1 | 0.0383676 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0357368 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0340649 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.033681 |
| SMAD3 | SMAD family member 3 | 0.032855 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0319362 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0319058 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0313009 |
| TNS3 | tensin 3 | 0.0303138 |
| SEPTIN9 | septin 9 | 0.0277251 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0269609 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0263813 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0247956 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0241432 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0236638 |
| RUNX2 | runt-related transcription factor 2 | 0.0235006 |
| VCL | vinculin | 0.0234047 |
| CANX | calnexin | 0.0233954 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0232503 |
| FLNA | filamin A, alpha | 0.022272 |
| KIAA1217 | KIAA1217 | 0.0220456 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0218687 |
| RPS4X | ribosomal protein S4, X-linked | 0.0216025 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0210962 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0206117 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0203848 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0203665 |
| GPR15 | G protein-coupled receptor 15 | 0.0201913 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0195285 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0194528 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0193501 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0189743 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0188697 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0183244 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0181533 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0179761 |
| FNIP1 | folliculin interacting protein 1 | 0.0177576 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0176764 |
| PRELID2 | PRELI domain containing 2 | 0.0175265 |
| HSPA8 | heat shock 70kDa protein 8 | 0.017386 |
| GOLGB1 | golgin B1 | 0.017364 |
| KIZ | kizuna centrosomal protein | 0.017057 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0163928 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0163753 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0163387 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | 0.0162416 |
| PHF3 | PHD finger protein 3 | 0.0158313 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.015809 |
| EXT1 | exostosin glycosyltransferase 1 | 0.015792 |
| EXOC6B | exocyst complex component 6B | 0.0153544 |
| EXOC4 | exocyst complex component 4 | 0.015259 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0147855 |
| FSTL4 | follistatin-like 4 | 0.0147809 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0143953 |
| MYOF | myoferlin | 0.0142966 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0141799 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0141105 |
| MACROD2 | MACRO domain containing 2 | 0.0140979 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0140877 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0140728 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0140261 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.0138812 |
| CDK13 | cyclin-dependent kinase 13 | 0.0137913 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0134474 |
| ZNRF3 | zinc and ring finger 3 | 0.01344 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0133349 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0133045 |
| FOXN3 | forkhead box N3 | 0.0132873 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0132636 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0130435 |
| TOM1L2 | target of myb1-like 2 (chicken) | 0.0130317 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0129392 |
| TMF1 | TATA element modulatory factor 1 | 0.01289 |
| NEBL | nebulette | 0.0128579 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0127045 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0126849 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0126548 |
| EVA1C | eva-1 homolog C (C. elegans) | 0.012429 |
| AEBP2 | AE binding protein 2 | 0.0124197 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0123426 |
| UBN2 | ubinuclein 2 | 0.0123359 |
| FAAH2 | fatty acid amide hydrolase 2 | 0.0122969 |
| SP100 | SP100 nuclear antigen | 0.0122702 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | 0.0122594 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0122082 |
| FLOT1 | flotillin 1 | 0.0122005 |
| RNF213 | ring finger protein 213 | 0.0121876 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0119497 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0117957 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0117522 |
| USO1 | USO1 vesicle transport factor | 0.0116539 |
| H1-2 | H1.2 linker histone, cluster member | 0.0116377 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.0115398 |
| WWOX | WW domain containing oxidoreductase | 0.0115064 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.011499 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.230082 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.178713 |
| TMSB10 | thymosin beta 10 | -0.156593 |
| AREG | amphiregulin | -0.155374 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.14492 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.133551 |
| IER3 | immediate early response 3 | -0.125353 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.112301 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.106793 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0961938 |
| ANXA2 | annexin A2 | -0.0882627 |
| HMGA2 | high mobility group AT-hook 2 | -0.083362 |
| ACTG1 | actin gamma 1 | -0.0824662 |
| FERMT1 | fermitin family member 1 | -0.0764536 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0746502 |
| RPL35A | ribosomal protein L35a | -0.0743047 |
| NDRG1 | N-myc downstream regulated 1 | -0.0707541 |
| RPS6 | ribosomal protein S6 | -0.0706457 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0695013 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0670602 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0662635 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0660747 |
| LAMB3 | laminin, beta 3 | -0.0657826 |
| RPS24 | ribosomal protein S24 | -0.0600583 |
| RBM25 | RNA binding motif protein 25 | -0.0595356 |
| EZR | ezrin | -0.0589779 |
| TXNRD1 | thioredoxin reductase 1 | -0.0576792 |
| LAMC2 | laminin, gamma 2 | -0.0572843 |
| EGR1 | early growth response 1 | -0.056951 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0567095 |
| HMGA1 | high mobility group AT-hook 1 | -0.052218 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0509931 |
| TOP1 | topoisomerase (DNA) I | -0.0509428 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0507864 |
| ANXA1 | annexin A1 | -0.0507591 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0497043 |
| RCOR1 | REST corepressor 1 | -0.0496542 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0489943 |
| EREG | epiregulin | -0.0484216 |
| S100A6 | S100 calcium binding protein A6 | -0.0479363 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.046551 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0438274 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0436396 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0433137 |
| S100A10 | S100 calcium binding protein A10 | -0.0431445 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0419982 |
| RPL37A | ribosomal protein L37a | -0.0416576 |
| MT2A | metallothionein 2A | -0.0416234 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0415147 |
| SNX9 | sorting nexin 9 | -0.0411141 |
| LMO7 | LIM domain 7 | -0.0407295 |
| FAM3C | family with sequence similarity 3, member C | -0.040607 |
| RPS8 | ribosomal protein S8 | -0.0405255 |
| COG5 | component of oligomeric golgi complex 5 | -0.0402903 |
| RPL5 | ribosomal protein L5 | -0.0400681 |
| ITGA6 | integrin, alpha 6 | -0.0400316 |
| LDHA | lactate dehydrogenase A | -0.0398178 |
| RPL34 | ribosomal protein L34 | -0.0397801 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0394624 |
| PKM | pyruvate kinase, muscle | -0.0393897 |
| RPLP1 | ribosomal protein, large, P1 | -0.0391036 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0388717 |
| RPS27A | ribosomal protein S27a | -0.0383063 |
| UBC | ubiquitin C | -0.037642 |
| FOSL1 | FOS-like antigen 1 | -0.0365218 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0362739 |
| RPS19 | ribosomal protein S19 | -0.0360775 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0354811 |
| RPLP2 | ribosomal protein, large, P2 | -0.0353845 |
| GOLGA4 | golgin A4 | -0.0352917 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0344492 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0342179 |
| RPL26 | ribosomal protein L26 | -0.0335515 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.033325 |
| RPS29 | ribosomal protein S29 | -0.0330217 |
| RREB1 | ras responsive element binding protein 1 | -0.0329278 |
| ENO1 | enolase 1, (alpha) | -0.0328286 |
| FMNL2 | formin-like 2 | -0.0319742 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0316199 |
| RBM39 | RNA binding motif protein 39 | -0.0316098 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0313338 |
| KLK10 | kallikrein-related peptidase 10 | -0.0312598 |
| USP3 | ubiquitin specific peptidase 3 | -0.0311521 |
| AHNAK | AHNAK nucleoprotein | -0.0308391 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.030794 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0305995 |
| MYO5B | myosin VB | -0.0305657 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0299957 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0299436 |
| MT1X | metallothionein 1X | -0.0297047 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0296924 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.029501 |
| RNF145 | ring finger protein 145 | -0.029358 |
| S100A11 | S100 calcium binding protein A11 | -0.0292375 |
| RPL32 | ribosomal protein L32 | -0.0290297 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.0290072 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0289883 |
| RPL36 | ribosomal protein L36 | -0.0288746 |
| NEMF | nuclear export mediator factor | -0.0288329 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0286005 |
