| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elimusertib hydrochloride perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Elimusertib hydrochloride_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.428762 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.263537 |
| TNS3 | tensin 3 | 0.147926 |
| DSPP | dentin sialophosphoprotein | 0.141085 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0922036 |
| AXIN2 | axin 2 | 0.076118 |
| SERINC5 | serine incorporator 5 | 0.0736536 |
| KIZ | kizuna centrosomal protein | 0.0640796 |
| KRT18 | keratin 18, type I | 0.0613182 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.059141 |
| CANX | calnexin | 0.056588 |
| LDHA | lactate dehydrogenase A | 0.0552734 |
| VIM | vimentin | 0.0549316 |
| PCDH9 | protocadherin 9 | 0.0545255 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0444144 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0437262 |
| AHNAK | AHNAK nucleoprotein | 0.0433951 |
| VCL | vinculin | 0.0418463 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0407614 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0407164 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | 0.0406075 |
| SPATA13 | spermatogenesis associated 13 | 0.0404057 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0386724 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0381907 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0373762 |
| SMOC2 | SPARC related modular calcium binding 2 | 0.0371127 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0365651 |
| ZNRF3 | zinc and ring finger 3 | 0.036414 |
| SYK | spleen tyrosine kinase | 0.035143 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0346449 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0344912 |
| PERP | PERP, TP53 apoptosis effector | 0.0337554 |
| EPHB2 | EPH receptor B2 | 0.0314603 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0307873 |
| ARHGAP18 | Rho GTPase activating protein 18 | 0.0298318 |
| ANXA3 | annexin A3 | 0.0292782 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0288197 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0278978 |
| STK38L | serine/threonine kinase 38 like | 0.0274705 |
| WWOX | WW domain containing oxidoreductase | 0.026977 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0261923 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0258705 |
| KREMEN1 | kringle containing transmembrane protein 1 | 0.0252098 |
| PPL | periplakin | 0.0251895 |
| RPS4X | ribosomal protein S4, X-linked | 0.0250459 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0245898 |
| AOPEP | aminopeptidase O (putative) | 0.024394 |
| TOX3 | TOX high mobility group box family member 3 | 0.0242151 |
| CALR | calreticulin | 0.0238623 |
| BMP5 | bone morphogenetic protein 5 | 0.0236616 |
| SEPTIN9 | septin 9 | 0.0235138 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0233504 |
| CDH13 | cadherin 13 | 0.0224808 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0222572 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0220282 |
| FLNA | filamin A, alpha | 0.0219659 |
| RNF213 | ring finger protein 213 | 0.0215195 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0214047 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0211882 |
| CNTNAP2 | contactin associated protein-like 2 | 0.020997 |
| NOTUM | notum pectinacetylesterase homolog (Drosophila) | 0.0208667 |
| RPL4 | ribosomal protein L4 | 0.0207677 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | 0.0207375 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0206826 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.020443 |
| EZR | ezrin | 0.020305 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0202057 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0198816 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0198343 |
| CDK6 | cyclin-dependent kinase 6 | 0.019756 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0197426 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0195949 |
| KRT19 | keratin 19, type I | 0.0192343 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0192164 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.019127 |
| CEP250 | centrosomal protein 250kDa | 0.0189556 |
| GLI3 | GLI family zinc finger 3 | 0.0181824 |
| CMIP | c-Maf inducing protein | 0.0178605 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0178473 |
| RPL14 | ribosomal protein L14 | 0.0177853 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0177835 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0176291 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.017516 |
| CEP112 | centrosomal protein 112kDa | 0.0172954 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.017281 |
| ACTN4 | actinin, alpha 4 | 0.0172754 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0172318 |
| EPCAM | epithelial cell adhesion molecule | 0.0172233 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0169569 |
| GOLGB1 | golgin B1 | 0.0168554 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | 0.0167299 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0167169 |
| CD9 | CD9 molecule | 0.0167016 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0166513 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0166424 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0166276 |
| SH3BGRL2 | SH3 domain binding glutamate-rich protein like 2 | 0.0165998 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0164194 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0163953 |
| UBC | ubiquitin C | 0.0163764 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAV2 | neuron navigator 2 | -0.140548 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0971598 |
| RPL35A | ribosomal protein L35a | -0.0928031 |
| RPS19 | ribosomal protein S19 | -0.077021 |
| TMSB10 | thymosin beta 10 | -0.0722601 |
| RPL37A | ribosomal protein L37a | -0.0694975 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0651168 |
| RPLP2 | ribosomal protein, large, P2 | -0.0646638 |
| EGR1 | early growth response 1 | -0.0633793 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0607922 |
| RPLP1 | ribosomal protein, large, P1 | -0.0604475 |
| RPS6 | ribosomal protein S6 | -0.0586727 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0579966 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0575265 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0541293 |
| DIAPH3 | diaphanous-related formin 3 | -0.0540061 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0538073 |
| RPS3 | ribosomal protein S3 | -0.0534508 |
| MT2A | metallothionein 2A | -0.0519206 |
| RPL26 | ribosomal protein L26 | -0.0509338 |
| RPS12 | ribosomal protein S12 | -0.0496511 |
| RPL31 | ribosomal protein L31 | -0.0479073 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0469956 |
| HMGA1 | high mobility group AT-hook 1 | -0.0465439 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0457094 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0452945 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0444425 |
| ASPH | aspartate beta-hydroxylase | -0.0440105 |
| ITGA6 | integrin, alpha 6 | -0.0432388 |
| RPL11 | ribosomal protein L11 | -0.0420158 |
| RPL36 | ribosomal protein L36 | -0.0418868 |
| RPL28 | ribosomal protein L28 | -0.0418636 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0415161 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0405089 |
| VMP1 | vacuole membrane protein 1 | -0.0404722 |
| TNS4 | tensin 4 | -0.0404018 |
| FTL | ferritin, light polypeptide | -0.0400348 |
| RBM25 | RNA binding motif protein 25 | -0.0387964 |
| ANLN | anillin, actin binding protein | -0.0367575 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0366831 |
| RPS25 | ribosomal protein S25 | -0.0363036 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0360546 |
| RBM39 | RNA binding motif protein 39 | -0.0359863 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0358266 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0354531 |
| POTEF | POTE ankyrin domain family, member F | -0.0352244 |
| ACTG1 | actin gamma 1 | -0.035182 |
| RPL23 | ribosomal protein L23 | -0.0350071 |
| RPS24 | ribosomal protein S24 | -0.0349939 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0349241 |
| RPL9 | ribosomal protein L9 | -0.0349104 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0345387 |
| RPL5 | ribosomal protein L5 | -0.0331828 |
| GPHN | gephyrin | -0.0323489 |
| THOC2 | THO complex 2 | -0.0322922 |
| RPL32 | ribosomal protein L32 | -0.0317298 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0315064 |
| RPS21 | ribosomal protein S21 | -0.0310545 |
| RPS29 | ribosomal protein S29 | -0.030772 |
| FRMD5 | FERM domain containing 5 | -0.0307599 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0306198 |
| FLNB | filamin B, beta | -0.0304889 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0304275 |
| ARF4 | ADP-ribosylation factor 4 | -0.0302302 |
| PFN1 | profilin 1 | -0.0300117 |
| SYT1 | synaptotagmin I | -0.0299771 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0297678 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0294614 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0290965 |
| MORF4L2 | mortality factor 4 like 2 | -0.0288623 |
| NDRG1 | N-myc downstream regulated 1 | -0.0284805 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0275576 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0273094 |
| RPL36A | ribosomal protein L36a | -0.0269219 |
| CBFB | core-binding factor, beta subunit | -0.0265575 |
| NKTR | natural killer cell triggering receptor | -0.026271 |
| EFNB2 | ephrin-B2 | -0.0258285 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0256451 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0255393 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.0254848 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.025476 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0254019 |
| ETV5 | ets variant 5 | -0.0252905 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0252071 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0251603 |
| CCNL1 | cyclin L1 | -0.0250373 |
| RPL37 | ribosomal protein L37 | -0.0250206 |
| RPL35 | ribosomal protein L35 | -0.0249799 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0248549 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.024838 |
| HDAC4 | histone deacetylase 4 | -0.0244645 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.0244541 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.024449 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0239266 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0238737 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0237768 |
| COG5 | component of oligomeric golgi complex 5 | -0.0237293 |
| CENPF | centromere protein F, 350/400kDa | -0.0235679 |
| ECT2 | epithelial cell transforming 2 | -0.0234566 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0233168 |
