Embryonal Carcinoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An embryonal cancer that is a type of germ cell tumour that is located_in the ovaries or located_in the testes. (Human Disease Ontology, DOID_3308)
External Link https://www.disgenet.org/browser/0/1/0/C0206659
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Genes

151 genes associated with the disease Embryonal Carcinoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACTB actin, beta
AFP alpha-fetoprotein
ALPL alkaline phosphatase, liver/bone/kidney
ATRX alpha thalassemia/mental retardation syndrome X-linked
BMP2 bone morphogenetic protein 2
BOC BOC cell adhesion associated, oncogene regulated
BRAF B-Raf proto-oncogene, serine/threonine kinase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CBX3 chromobox homolog 3
CBX7 chromobox homolog 7
CCND2 cyclin D2
CD274 CD274 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK4 cyclin-dependent kinase 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CENPA centromere protein A
CGB chorionic gonadotropin, beta polypeptide
CGB5 chorionic gonadotropin, beta polypeptide 5
CGB8 chorionic gonadotropin, beta polypeptide 8
CHEK2 checkpoint kinase 2
CHGB chromogranin B
CIB1 calcium and integrin binding 1 (calmyrin)
CISH cytokine inducible SH2-containing protein
CKAP4 cytoskeleton-associated protein 4
CKS1B CDC28 protein kinase regulatory subunit 1B
CLSTN1 calsyntenin 1
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen)
CSH2 chorionic somatomammotropin hormone 2
CXCL12 chemokine (C-X-C motif) ligand 12
DAXX death-domain associated protein
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
DES desmin
DLK1 delta-like 1 homolog (Drosophila)
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like
DRD2 dopamine receptor D2
EGFR epidermal growth factor receptor
EMB embigin
ERF Ets2 repressor factor
ETV6 ets variant 6
F9 coagulation factor IX
FAS Fas cell surface death receptor
FGF2 fibroblast growth factor 2 (basic)
FGF4 fibroblast growth factor 4
FGF9 fibroblast growth factor 9
FN1 fibronectin 1
FOXO1 forkhead box O1
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
FXYD5 FXYD domain containing ion transport regulator 5
FZD7 frizzled class receptor 7
GAP43 growth associated protein 43
GDF3 growth differentiation factor 3
GSTP1 glutathione S-transferase pi 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2A2 general transcription factor IIA, 2, 12kDa
HDAC1 histone deacetylase 1
HLA-A major histocompatibility complex, class I, A
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2
HPX hemopexin
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IFNB1 interferon, beta 1, fibroblast
IGF2 insulin-like growth factor 2
IL23A interleukin 23, alpha subunit p19
ITPRID2 ITPR interacting domain containing 2
JAG2 jagged 2
KDM3A lysine (K)-specific demethylase 3A
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF6 Kruppel-like factor 6
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT18 keratin 18, type I
KRT7 keratin 7, type II
LCN2 lipocalin 2
LEFTY2 left-right determination factor 2
LIF leukemia inhibitory factor
MAPK15 mitogen-activated protein kinase 15
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIB1 mindbomb E3 ubiquitin protein ligase 1
MKI67 marker of proliferation Ki-67
MOK MOK protein kinase
MOS v-mos Moloney murine sarcoma viral oncogene homolog
MTTP microsomal triglyceride transfer protein
MYD88 myeloid differentiation primary response 88
MYOZ2 myozenin 2
NANOG Nanog homeobox
NME2 NME/NM23 nucleoside diphosphate kinase 2
NODAL nodal growth differentiation factor
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOTCH1 notch 1
NR5A1 nuclear receptor subfamily 5, group A, member 1
NRIP1 nuclear receptor interacting protein 1
NUCLEOLIN nucleolin multifunctional protein
PCNA proliferating cell nuclear antigen
PHGDH phosphoglycerate dehydrogenase
PLSCR4 phospholipid scramblase 4
PODXL podocalyxin-like
POU5F1 POU class 5 homeobox 1
PRAME preferentially expressed antigen in melanoma
PRDM14 PR domain containing 14
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTCH1 patched 1
PTEN phosphatase and tensin homolog
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RARB retinoic acid receptor, beta
RARG retinoic acid receptor, gamma
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBL2 retinoblastoma-like 2
RCC1 regulator of chromosome condensation 1
REG1A regenerating islet-derived 1 alpha
RPE65 retinal pigment epithelium-specific protein 65kDa
SINHCAF SIN3-HDAC complex associated factor
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLAMF7 SLAM family member 7
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SOX17 SRY (sex determining region Y)-box 17
SOX2 SRY (sex determining region Y)-box 2
SPAG1 sperm associated antigen 1
SPANXA1 sperm protein associated with the nucleus, X-linked, family member A1
SPANXA2 SPANX family, member A2
STK17A serine/threonine kinase 17a
TBP TATA box binding protein
TCF3 transcription factor 3
TDGF1 teratocarcinoma-derived growth factor 1
TDGF1P3 teratocarcinoma-derived growth factor 1 pseudogene 3
TGFB2 transforming growth factor, beta 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TH tyrosine hydroxylase
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8
TP53 tumor protein p53
TP63 tumor protein p63
TPD52 tumor protein D52
TRRAP transformation/transcription domain-associated protein
TSKS testis-specific serine kinase substrate
UBE3B ubiquitin protein ligase E3B
UTF1 undifferentiated embryonic cell transcription factor 1
UVRAG UV radiation resistance associated
VCP valosin containing protein
VIM vimentin
ZFP42 ZFP42 zinc finger protein
ZNF202 zinc finger protein 202
ZNF354A zinc finger protein 354A