Emodin Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A member of the class of hydroxyanthraquinones that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs. (Chemical Entities of Biological Interest Ontology, CHEBI_42223)
External Link http://ctdbase.org/detail.go?type=chem&acc=D004642
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Genes

57 genes/proteins interacting with the chemical Emodin from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACTA2 actin, alpha 2, smooth muscle, aorta
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ATM ATM serine/threonine kinase
BCL2 B-cell CLL/lymphoma 2
BIRC5 baculoviral IAP repeat containing 5
CASP3 caspase 3, apoptosis-related cysteine peptidase
COPS5 COP9 signalosome subunit 5
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
H2AFX H2A histone family, member X
ICAM1 intercellular adhesion molecule 1
IFNA2 interferon, alpha 2
IL13 interleukin 13
IL4 interleukin 4
IL5 interleukin 5
IL6 interleukin 6
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JUND jun D proto-oncogene
MAOB monoamine oxidase B
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MCL1 myeloid cell leukemia 1
MPO myeloperoxidase
MYLK myosin light chain kinase
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS2 nitric oxide synthase 2, inducible
PARP1 poly (ADP-ribose) polymerase 1
PDGFB platelet-derived growth factor beta polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PECAM1 platelet/endothelial cell adhesion molecule 1
PRKCA protein kinase C, alpha
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor
TOP2A topoisomerase (DNA) II alpha 170kDa
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
VEGFA vascular endothelial growth factor A