| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Encorafenib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Encorafenib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.0981538 |
| RNF213 | ring finger protein 213 | 0.0946526 |
| TLE4 | transducin-like enhancer of split 4 | 0.0778727 |
| PRKCA | protein kinase C, alpha | 0.0693632 |
| RIGI | RNA sensor RIG-I | 0.0565304 |
| SYT1 | synaptotagmin I | 0.0536833 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0499233 |
| MEIS2 | Meis homeobox 2 | 0.0495253 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0486588 |
| ENAH | enabled homolog (Drosophila) | 0.0474327 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0459122 |
| MYO6 | myosin VI | 0.0425416 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0424496 |
| THBS1 | thrombospondin 1 | 0.0419968 |
| BPTF | bromodomain PHD finger transcription factor | 0.0400742 |
| FMN1 | formin 1 | 0.0392065 |
| ACTG1 | actin gamma 1 | 0.0371499 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0363631 |
| ANGPT1 | angiopoietin 1 | 0.0362938 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0340053 |
| SYNPO2 | synaptopodin 2 | 0.0311351 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0310182 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0306562 |
| LPIN1 | lipin 1 | 0.0305203 |
| RET | ret proto-oncogene | 0.0299499 |
| FERMT2 | fermitin family member 2 | 0.0298389 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0295632 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0293648 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0283174 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0278561 |
| SP100 | SP100 nuclear antigen | 0.0270139 |
| MED13L | mediator complex subunit 13-like | 0.0268249 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0267127 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0265001 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0264766 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0249835 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0245639 |
| RAD51B | RAD51 paralog B | 0.024455 |
| CLTC | clathrin, heavy chain (Hc) | 0.0241208 |
| RALYL | RALY RNA binding protein-like | 0.0240126 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0231884 |
| CYTH1 | cytohesin 1 | 0.0227427 |
| PLPP1 | phospholipid phosphatase 1 | 0.0222616 |
| TRIM25 | tripartite motif containing 25 | 0.0222268 |
| EGR1 | early growth response 1 | 0.0220986 |
| EXOC4 | exocyst complex component 4 | 0.0217581 |
| TPM1 | tropomyosin 1 (alpha) | 0.0216978 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.021245 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0211433 |
| ITGA1 | integrin, alpha 1 | 0.0209175 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.0205367 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0204225 |
| EP300 | E1A binding protein p300 | 0.0203229 |
| RBM39 | RNA binding motif protein 39 | 0.0202972 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0202857 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0200319 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0200108 |
| PCDH7 | protocadherin 7 | 0.0199242 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0198604 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0198312 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0198304 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0198053 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0197129 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0196251 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.01958 |
| CREBBP | CREB binding protein | 0.0195625 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0192115 |
| FAT4 | FAT atypical cadherin 4 | 0.0192013 |
| MX1 | MX dynamin-like GTPase 1 | 0.0189355 |
| INTS6 | integrator complex subunit 6 | 0.0185544 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0183071 |
| MYO1E | myosin IE | 0.0182188 |
| TRIB2 | tribbles pseudokinase 2 | 0.0182056 |
| CEP350 | centrosomal protein 350kDa | 0.0181729 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0180593 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0178705 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0178217 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | 0.0177328 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0176435 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0175285 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0175244 |
| TENM4 | teneurin transmembrane protein 4 | 0.0175078 |
| TLK2 | tousled-like kinase 2 | 0.0174689 |
| SMYD3 | SET and MYND domain containing 3 | 0.0174323 |
| PHF3 | PHD finger protein 3 | 0.0173201 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0172578 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0172239 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0171439 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0171029 |
| ANK2 | ankyrin 2, neuronal | 0.0170583 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.0168464 |
| FHL2 | four and a half LIM domains 2 | 0.0166895 |
| EXOC6B | exocyst complex component 6B | 0.0161177 |
| JMJD1C | jumonji domain containing 1C | 0.0160911 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0160778 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0160753 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0159824 |
| GPATCH8 | G patch domain containing 8 | 0.0159435 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0159203 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0158049 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.218474 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.156496 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.123536 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0952093 |
| LSAMP | limbic system-associated membrane protein | -0.0698703 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0666007 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0609365 |
| PTMA | prothymosin, alpha | -0.0566429 |
| STC1 | stanniocalcin 1 | -0.055486 |
| MAP1B | microtubule-associated protein 1B | -0.0549621 |
| NRG1 | neuregulin 1 | -0.049747 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0445712 |
| PLAT | plasminogen activator, tissue | -0.0422468 |
| COL1A1 | collagen, type I, alpha 1 | -0.0399393 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0397032 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0369037 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0352756 |
| RPS6 | ribosomal protein S6 | -0.0351818 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0347465 |
| NDRG1 | N-myc downstream regulated 1 | -0.0342597 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0330258 |
| FNDC3B | fibronectin type III domain containing 3B | -0.032915 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0310058 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0307405 |
| DIAPH2 | diaphanous-related formin 2 | -0.0306464 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0288544 |
| IER3 | immediate early response 3 | -0.0287992 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0286993 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0269656 |
| RPL23 | ribosomal protein L23 | -0.0268868 |
| TMSB10 | thymosin beta 10 | -0.0266962 |
| VGF | VGF nerve growth factor inducible | -0.0266889 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0259846 |
| FN1 | fibronectin 1 | -0.0259127 |
| NREP | neuronal regeneration related protein | -0.0257343 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0251195 |
| DNM3 | dynamin 3 | -0.0244316 |
| CRH | corticotropin releasing hormone | -0.0244262 |
| HMGA2 | high mobility group AT-hook 2 | -0.0243381 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0239853 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0238768 |
| S100A9 | S100 calcium binding protein A9 | -0.0231646 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0230541 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0224757 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0217148 |
| RPS24 | ribosomal protein S24 | -0.0215186 |
| RPLP1 | ribosomal protein, large, P1 | -0.0214877 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0214629 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0211319 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0211104 |
| RPL34 | ribosomal protein L34 | -0.020568 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0204535 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0203321 |
| RPL32 | ribosomal protein L32 | -0.0202399 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0201816 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.020134 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0201312 |
| RPS19 | ribosomal protein S19 | -0.0198335 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0197232 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0189684 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0186412 |
| CENPF | centromere protein F, 350/400kDa | -0.0184281 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0184175 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0181706 |
| CDH13 | cadherin 13 | -0.0181586 |
| SCG2 | secretogranin II | -0.017985 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0178763 |
| ZFHX3 | zinc finger homeobox 3 | -0.0178597 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0178514 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0178182 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0177914 |
| FAM162A | family with sequence similarity 162, member A | -0.0177016 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0176361 |
| S100A6 | S100 calcium binding protein A6 | -0.0174733 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0174726 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0171418 |
| PCNX1 | pecanex 1 | -0.0171209 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0171127 |
| KLHL13 | kelch-like family member 13 | -0.0169959 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.016796 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0161375 |
| VIM | vimentin | -0.0160564 |
| VCAN | versican | -0.0159953 |
| SETBP1 | SET binding protein 1 | -0.0159732 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0158492 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0157128 |
| GAB2 | GRB2-associated binding protein 2 | -0.0156992 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | -0.0156272 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0155746 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0154555 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0151114 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0150671 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0150573 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0149677 |
| RPL8 | ribosomal protein L8 | -0.0149618 |
| HMGA1 | high mobility group AT-hook 1 | -0.0148541 |
| RAI14 | retinoic acid induced 14 | -0.0148199 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0147669 |
| RPS14 | ribosomal protein S14 | -0.0147481 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0145552 |
