| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Encorafenib perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Encorafenib_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.254407 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.151437 |
| FN1 | fibronectin 1 | 0.0946294 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0944704 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0870606 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0850714 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0815086 |
| EXT1 | exostosin glycosyltransferase 1 | 0.076193 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0732312 |
| NDRG1 | N-myc downstream regulated 1 | 0.0655294 |
| CDH13 | cadherin 13 | 0.0650794 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0639131 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0629504 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0625835 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.06038 |
| ATXN1 | ataxin 1 | 0.0571938 |
| PGK1 | phosphoglycerate kinase 1 | 0.0569901 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0543021 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.053537 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.052948 |
| CD44 | CD44 molecule (Indian blood group) | 0.0518116 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0509488 |
| DST | dystonin | 0.0507623 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0504739 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0502124 |
| PTK2 | protein tyrosine kinase 2 | 0.050038 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0497783 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0488358 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0484966 |
| COL5A2 | collagen, type V, alpha 2 | 0.0482945 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0480793 |
| VMP1 | vacuole membrane protein 1 | 0.0476206 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0476025 |
| PDE10A | phosphodiesterase 10A | 0.0471171 |
| RPLP1 | ribosomal protein, large, P1 | 0.0468201 |
| YTHDC1 | YTH domain containing 1 | 0.0466599 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0462234 |
| VIM | vimentin | 0.046212 |
| EGFR | epidermal growth factor receptor | 0.0459781 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0455369 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0454764 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0454119 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0444664 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0443712 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0440156 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0435717 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0434718 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0424416 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.042075 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0410928 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0410671 |
| LSAMP | limbic system-associated membrane protein | 0.0402455 |
| KYNU | kynureninase | 0.040238 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0400186 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0398151 |
| MAP7 | microtubule-associated protein 7 | 0.0398065 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0393149 |
| AREG | amphiregulin | 0.0390847 |
| INTS6 | integrator complex subunit 6 | 0.038739 |
| TRIM2 | tripartite motif containing 2 | 0.0379154 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0377559 |
| RPL37 | ribosomal protein L37 | 0.037744 |
| GPC6 | glypican 6 | 0.0376452 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0375226 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0374032 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0372414 |
| RNF145 | ring finger protein 145 | 0.0371013 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0370725 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0365837 |
| WWC1 | WW and C2 domain containing 1 | 0.0364521 |
| NRXN3 | neurexin 3 | 0.0361552 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0361466 |
| CTBP2 | C-terminal binding protein 2 | 0.0361094 |
| CALD1 | caldesmon 1 | 0.0359167 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0353816 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0352419 |
| TNS3 | tensin 3 | 0.0351694 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0350297 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0347303 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0346925 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0346048 |
| HLA-A | major histocompatibility complex, class I, A | 0.0339036 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0337132 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0332988 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0332152 |
| GLIS3 | GLIS family zinc finger 3 | 0.0329264 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0326678 |
| RPL12 | ribosomal protein L12 | 0.0323593 |
| SBF2 | SET binding factor 2 | 0.0321941 |
| LAMC2 | laminin, gamma 2 | 0.0318922 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0318008 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.031629 |
| EGR1 | early growth response 1 | 0.0314229 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0313765 |
| RTN3 | reticulon 3 | 0.0312857 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0311552 |
| METTL15 | methyltransferase like 15 | 0.030762 |
| GLCCI1 | glucocorticoid induced 1 | 0.0307125 |
| KIF2A | kinesin heavy chain member 2A | 0.0306895 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0306833 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPEPPS | aminopeptidase puromycin sensitive | -0.12234 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.118578 |
| AHNAK | AHNAK nucleoprotein | -0.110977 |
| ATOSA | atos homolog A | -0.0994647 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0964411 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0952529 |
| LMO7 | LIM domain 7 | -0.0909497 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0902717 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0863968 |
| ABHD17C | abhydrolase domain containing 17C | -0.0717145 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0678668 |
| TXNIP | thioredoxin interacting protein | -0.0639332 |
| NEBL | nebulette | -0.0623658 |
| ANXA2 | annexin A2 | -0.0614046 |
| PARD3 | par-3 family cell polarity regulator | -0.0610758 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0606128 |
| KIAA1217 | KIAA1217 | -0.0581016 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0573761 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0567158 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0558764 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0557532 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0552496 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0549886 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0524286 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0515646 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.050238 |
| NBEA | neurobeachin | -0.0502068 |
| ENO1 | enolase 1, (alpha) | -0.0464275 |
| NF1 | neurofibromin 1 | -0.0458539 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0452465 |
| USP53 | ubiquitin specific peptidase 53 | -0.0449149 |
| KIAA1671 | KIAA1671 | -0.0445606 |
| OGA | O-GlcNAcase | -0.0443784 |
| ZNF638 | zinc finger protein 638 | -0.0440065 |
| FOXO3 | forkhead box O3 | -0.0427067 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0420225 |
| PERP | PERP, TP53 apoptosis effector | -0.0418055 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0417416 |
| LAMB3 | laminin, beta 3 | -0.0412579 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0412562 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.041182 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0406847 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0403276 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0400096 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0393796 |
| FMN1 | formin 1 | -0.0393473 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0386078 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.038498 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0383059 |
| HOOK3 | hook microtubule-tethering protein 3 | -0.0379396 |
| RIGI | RNA sensor RIG-I | -0.0379048 |
| PLS3 | plastin 3 | -0.0378755 |
| FAM13A | family with sequence similarity 13, member A | -0.0378683 |
| RBM47 | RNA binding motif protein 47 | -0.0377609 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0373159 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0363039 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0362056 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.036141 |
| LNPEP | leucyl/cystinyl aminopeptidase | -0.0361245 |
| CDC42 | cell division cycle 42 | -0.035944 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0353039 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0351173 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0351064 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0349985 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0349339 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0346402 |
| NCOA6 | nuclear receptor coactivator 6 | -0.0346028 |
| MTSS1 | metastasis suppressor 1 | -0.0344808 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | -0.0344369 |
| SQSTM1 | sequestosome 1 | -0.0343864 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0342877 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0341162 |
| FOXO1 | forkhead box O1 | -0.0340846 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0339401 |
| WDR45B | WD repeat domain 45B | -0.0338029 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0336774 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0334999 |
| WASF2 | WAS protein family, member 2 | -0.0334566 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0333506 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0332237 |
| DSG2 | desmoglein 2 | -0.0331195 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0331042 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.032764 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0327164 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.032578 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0325292 |
| SCEL | sciellin | -0.0324969 |
| MYO5C | myosin VC | -0.0324701 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0323567 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0321678 |
| UBAP1 | ubiquitin associated protein 1 | -0.0320598 |
| CDK12 | cyclin-dependent kinase 12 | -0.0319879 |
| GOLGB1 | golgin B1 | -0.0319203 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.0315891 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0315227 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0311984 |
| RBM25 | RNA binding motif protein 25 | -0.031074 |
| CYTH1 | cytohesin 1 | -0.0310215 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | -0.0309465 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0307887 |
