Endocarditis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A heart disease involving non-infectious inflammation of the endocardium (inner layer of the heart).|Inflammation of the inner lining of the heart (ENDOCARDIUM), the continuous membrane lining the four chambers and HEART VALVES. It is often caused by microorganisms including bacteria, viruses, fungi, and rickettsiae. Left untreated, endocarditis can damage heart valves and become life-threatening.|Inflammation of the endocardium. (Experimental Factor Ontology, EFO_0000465)
External Link https://www.disgenet.org/browser/0/1/0/C0014118
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Genes

55 genes associated with the disease Endocarditis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
AMBP alpha-1-microglobulin/bikunin precursor
APC adenomatous polyposis coli
APRT adenine phosphoribosyltransferase
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40
C4A complement component 4A (Rodgers blood group)
CALCA calcitonin-related polypeptide alpha
CALCR calcitonin receptor
CALR calreticulin
CCL3 chemokine (C-C motif) ligand 3
CCR1 chemokine (C-C motif) receptor 1
CHPT1 choline phosphotransferase 1
CS citrate synthase
DHDDS dehydrodolichyl diphosphate synthase
DNASE1 deoxyribonuclease I
ERAP1 endoplasmic reticulum aminopeptidase 1
F5 coagulation factor V (proaccelerin, labile factor)
FAS Fas cell surface death receptor
FBN1 fibrillin 1
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FN1 fibronectin 1
G6PD glucose-6-phosphate dehydrogenase
GP1BA glycoprotein Ib (platelet), alpha polypeptide
HCCS holocytochrome c synthase
HLA-B major histocompatibility complex, class I, B
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IL10 interleukin 10
IL12A interleukin 12A
IL1A interleukin 1, alpha
IL23R interleukin 23 receptor
KLRC4 killer cell lectin-like receptor subfamily C, member 4
MEFV Mediterranean fever
MFAP1 microfibrillar-associated protein 1
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MUC7 mucin 7, secreted
ODC1 ornithine decarboxylase 1
PHF20 PHD finger protein 20
PRAME preferentially expressed antigen in melanoma
PRF1 perforin 1 (pore forming protein)
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SESTD1 SEC14 and spectrin domains 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
SMOX spermine oxidase
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
STAT4 signal transducer and activator of transcription 4
TIMP2 TIMP metallopeptidase inhibitor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNIP1 TNFAIP3 interacting protein 1
UBAC2 UBA domain containing 2
UROD uroporphyrinogen decarboxylase
VWF von Willebrand factor