Endocytosis Gene Set

Dataset KEGG Pathways 2026
Category structural or functional annotations
Type pathway
Description A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. (Gene Ontology, GO_0006897)
External Link https://www.kegg.jp/entry/hsa04144
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Genes

248 proteins participating in the Endocytosis pathway from the KEGG Pathways 2026 dataset.

Symbol Name
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ACTR3C ARP3 actin-related protein 3 homolog C (yeast)
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4
AGAP5 ArfGAP with GTPase domain, ankyrin repeat and PH domain 5
AGAP6 ArfGAP with GTPase domain, ankyrin repeat and PH domain 6
AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9
AMPH amphiphysin
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARF1 ADP-ribosylation factor 1
ARF3 ADP-ribosylation factor 3
ARF4 ADP-ribosylation factor 4
ARF5 ADP-ribosylation factor 5
ARF6 ADP-ribosylation factor 6
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
ARPC4-TTLL3 ARPC4-TTLL3 readthrough
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ARPC5L actin related protein 2/3 complex, subunit 5-like
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BIN1 bridging integrator 1
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2
CAPZA3 capping protein (actin filament) muscle Z-line, alpha 3
CAPZB capping protein (actin filament) muscle Z-line, beta
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CAV3 caveolin 3
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CDC42 cell division cycle 42
CHMP1A charged multivesicular body protein 1A
CHMP1B charged multivesicular body protein 1B
CHMP2A charged multivesicular body protein 2A
CHMP2B charged multivesicular body protein 2B
CHMP4B charged multivesicular body protein 4B
CHMP4C charged multivesicular body protein 4C
CHMP5 charged multivesicular body protein 5
CHMP6 charged multivesicular body protein 6
CHMP7 charged multivesicular body protein 7
CLTA clathrin, light chain A
CLTB clathrin, light chain B
CLTC clathrin, heavy chain (Hc)
CLTCL1 clathrin, heavy chain-like 1
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYTH1 cytohesin 1
CYTH2 cytohesin 2
CYTH3 cytohesin 3
CYTH4 cytohesin 4
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DNM1 dynamin 1
DNM2 dynamin 2
DNM3 dynamin 3
EEA1 early endosome antigen 1
EGFR epidermal growth factor receptor
EHD1 EH-domain containing 1
EHD2 EH-domain containing 2
EHD3 EH-domain containing 3
EHD4 EH-domain containing 4
EPN1 epsin 1
EPN2 epsin 2
EPN3 epsin 3
EPS15 epidermal growth factor receptor pathway substrate 15
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
FBXL15 F-box and leucine-rich repeat protein 15
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FOLR2 folate receptor 2 (fetal)
FOLR3 folate receptor 3 (gamma)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GRK1 G protein-coupled receptor kinase 1
GRK2 G protein-coupled receptor kinase 2
GRK3 G protein-coupled receptor kinase 3
GRK4 G protein-coupled receptor kinase 4
GRK5 G protein-coupled receptor kinase 5
GRK6 G protein-coupled receptor kinase 6
GRK7 G protein-coupled receptor kinase 7
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HSPA1L heat shock 70kDa protein 1-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
IGF1R insulin-like growth factor 1 receptor
IGF2R insulin-like growth factor 2 receptor
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
IQSEC1 IQ motif and Sec7 domain 1
IQSEC2 IQ motif and Sec7 domain 2
IQSEC3 IQ motif and Sec7 domain 3
IST1 increased sodium tolerance 1 homolog (yeast)
ITCH itchy E3 ubiquitin protein ligase
KIF5A kinesin family member 5A
KIF5B kinesin family member 5B
KIF5C kinesin family member 5C
LDLR low density lipoprotein receptor
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LOC124908102 WAS protein family homolog 2-like
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MVB12A multivesicular body subunit 12A
MVB12B multivesicular body subunit 12B
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
PARD3 par-3 family cell polarity regulator
PARD6A par-6 family cell polarity regulator alpha
PARD6B par-6 family cell polarity regulator beta
PARD6G par-6 family cell polarity regulator gamma
PDCD6IP programmed cell death 6 interacting protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PIP5KL1 phosphatidylinositol-4-phosphate 5-kinase-like 1
PLD2 phospholipase D2
PML promyelocytic leukemia
PRKCI protein kinase C, iota
PRKCSH protein kinase C substrate 80K-H
PRKCZ protein kinase C, zeta
PSD2 pleckstrin and Sec7 domain containing 2
PSD3 pleckstrin and Sec7 domain containing 3
PSD4 pleckstrin and Sec7 domain containing 4
PTGES2 prostaglandin E synthase 2
RAB10 RAB10, member RAS oncogene family
RAB11A RAB11A, member RAS oncogene family
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB11FIP2 RAB11 family interacting protein 2 (class I)
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAB11FIP4 RAB11 family interacting protein 4 (class II)
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB22A RAB22A, member RAS oncogene family
RAB31 RAB31, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RAB43 RAB43, member RAS oncogene family
RAB4A RAB4A, member RAS oncogene family
RAB5A RAB5A, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RAB8A RAB8A, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RBSN rabenosyn, RAB effector
RHOA ras homolog family member A
RNF103-CHMP3 RNF103-CHMP3 readthrough
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RUFY1 RUN and FYVE domain containing 1
RUFY2 RUN and FYVE domain containing 2
SH3GL1 SH3-domain GRB2-like 1
SH3GL2 SH3-domain GRB2-like 2
SH3GL3 SH3-domain GRB2-like 3
SH3GLB1 SH3-domain GRB2-like endophilin B1
SH3GLB2 SH3-domain GRB2-like endophilin B2
SH3KBP1 SH3-domain kinase binding protein 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAP1 small ArfGAP 1
SMAP2 small ArfGAP2
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNF8 SNF8, ESCRT-II complex subunit
SNX1 sorting nexin 1
SNX12 sorting nexin 12
SNX2 sorting nexin 2
SNX3 sorting nexin 3
SNX32 sorting nexin 32
SNX4 sorting nexin 4
SNX5 sorting nexin 5
SNX6 sorting nexin 6
SPART spartin
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STAMBP STAM binding protein
TFRC transferrin receptor
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TSG101 tumor susceptibility 101
USP8 ubiquitin specific peptidase 8
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae)
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
VPS26B vacuolar protein sorting 26 homolog B (S. pombe)
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae)
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae)
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae)
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
VPS37D vacuolar protein sorting 37 homolog D (S. cerevisiae)
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
VTA1 vesicle (multivesicular body) trafficking 1
WASHC1 WASH complex subunit 1
WASHC2A WASH complex subunit 2A
WASHC2C WASH complex subunit 2C
WASHC3 WASH complex subunit 3
WASHC4 WASH complex subunit 4
WASHC5 WASH complex subunit 5
WASL Wiskott-Aldrich syndrome-like
WIPF1 WAS/WASL interacting protein family, member 1
WIPF2 WAS/WASL interacting protein family, member 2
WIPF3 WAS/WASL interacting protein family, member 3
WWP1 WW domain containing E3 ubiquitin protein ligase 1
ZFYVE16 zinc finger, FYVE domain containing 16
ZFYVE27 zinc finger, FYVE domain containing 27
ZFYVE9 zinc finger, FYVE domain containing 9