Endogenous Depression Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A mental depression that is characterized by a dysregulation of the endogenous opioid system and not of the monaminergic system. (Human Disease Ontology, DOID_1595)
External Link https://www.disgenet.org/browser/0/1/0/C0011573
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Genes

52 genes associated with the disease Endogenous Depression in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
ADORA2A adenosine A2a receptor
ALB albumin
APP amyloid beta (A4) precursor protein
BDNF brain-derived neurotrophic factor
CADM1 cell adhesion molecule 1
CNR2 cannabinoid receptor 2 (macrophage)
COMT catechol-O-methyltransferase
CREBBP CREB binding protein
CRH corticotropin releasing hormone
CSF3 colony stimulating factor 3 (granulocyte)
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DISC1 disrupted in schizophrenia 1
DIXDC1 DIX domain containing 1
DRD5 dopamine receptor D5
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FTH1 ferritin, heavy polypeptide 1
FTL ferritin, light polypeptide
GHRL ghrelin/obestatin prepropeptide
GLO1 glyoxalase I
GNAS GNAS complex locus
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HAP1 huntingtin-associated protein 1
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IFNA2 interferon, alpha 2
IL6 interleukin 6
KCNK2 potassium channel, two pore domain subfamily K, member 2
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MORC1 MORC family CW-type zinc finger 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NOS1 nitric oxide synthase 1 (neuronal)
NPY neuropeptide Y
NPY1R neuropeptide Y receptor Y1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PDCD2 programmed cell death 2
PDCD6 programmed cell death 6
POMC proopiomelanocortin
PON1 paraoxonase 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RELN reelin
S100A10 S100 calcium binding protein A10
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SNAP25 synaptosomal-associated protein, 25kDa
SOD1 superoxide dismutase 1, soluble
TG thyroglobulin
TPH2 tryptophan hydroxylase 2