Endolysosome Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description An transient hybrid organelle formed by fusion of a late endosome with a lysosome, and in which active degradation takes place. (Gene Ontology, GO_0036019)
External Link http://amigo.geneontology.org/amigo/term/GO:0036019
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Genes

26 proteins localized to the Endolysosome cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 5.0
PRKCD protein kinase C, delta 5.0
RNF167 ring finger protein 167 5.0
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4 5.0
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 5.0
TPCN2 two pore segment channel 2 5.0
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 5.0
TPCN1 two pore segment channel 1 5.0
CTSS cathepsin S 4.0
TLR8 toll-like receptor 8 4.0
TLR7 toll-like receptor 7 4.0
TLR3 toll-like receptor 3 4.0
PCSK9 proprotein convertase subtilisin/kexin type 9 4.0
AP2M1 adaptor-related protein complex 2, mu 1 subunit 4.0
CLTC clathrin, heavy chain (Hc) 4.0
CLTA clathrin, light chain A 4.0
LGMN legumain 4.0
CTSK cathepsin K 4.0
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 4.0
CTSL cathepsin L 4.0
CTSB cathepsin B 4.0
LDLR low density lipoprotein receptor 4.0
AP2A2 adaptor-related protein complex 2, alpha 2 subunit 4.0
AP2A1 adaptor-related protein complex 2, alpha 1 subunit 4.0
AP2B1 adaptor-related protein complex 2, beta 1 subunit 4.0
TLR9 toll-like receptor 9 4.0