Endometrial Adenocarcinoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An endometrial carcinoma that derives_from epithelial cells of glandular origin. (Human Disease Ontology, DOID_2870)
External Link https://www.disgenet.org/browser/0/1/0/C1153706
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Genes

199 genes associated with the disease Endometrial Adenocarcinoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACKR3 atypical chemokine receptor 3
ACTB actin, beta
ACVR2B activin A receptor, type IIB
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
AFP alpha-fetoprotein
AGTR1 angiotensin II receptor, type 1
AKR1C3 aldo-keto reductase family 1, member C3
AKT1 v-akt murine thymoma viral oncogene homolog 1
APC adenomatous polyposis coli
AR androgen receptor
ARID1A AT rich interactive domain 1A (SWI-like)
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
BSG basigin (Ok blood group)
CA12 carbonic anhydrase XII
CA2 carbonic anhydrase II
CA9 carbonic anhydrase IX
CCL20 chemokine (C-C motif) ligand 20
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CCR6 chemokine (C-C motif) receptor 6
CD109 CD109 molecule
CD68 CD68 molecule
CDC42SE2 CDC42 small effector 2
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK4 cyclin-dependent kinase 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CKAP4 cytoskeleton-associated protein 4
CLDN1 claudin 1
CLDN4 claudin 4
CLDN7 claudin 7
COX2
CRABP1 cellular retinoic acid binding protein 1
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSD cathepsin D
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
DAP death-associated protein
DAPK1 death-associated protein kinase 1
DLL1 delta-like 1 (Drosophila)
DUSP6 dual specificity phosphatase 6
EBAG9 estrogen receptor binding site associated, antigen, 9
EDN1 endothelin 1
EFNB2 ephrin-B2
EGFR epidermal growth factor receptor
EIF4E eukaryotic translation initiation factor 4E
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1
EPHA3 EPH receptor A3
EPHB2 EPH receptor B2
EPHB4 EPH receptor B4
EPO erythropoietin
ERBB2 erb-b2 receptor tyrosine kinase 2
ERRFI1 ERBB receptor feedback inhibitor 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FASN fatty acid synthase
FGF2 fibroblast growth factor 2 (basic)
FGF3 fibroblast growth factor 3
FGF7 fibroblast growth factor 7
FGFR2 fibroblast growth factor receptor 2
FKBP4 FK506 binding protein 4, 59kDa
FKBP5 FK506 binding protein 5
FOXC2 forkhead box C2
FOXL2 forkhead box L2
FOXO1 forkhead box O1
FOXR2 forkhead box R2
FST follistatin
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
G6PC glucose-6-phosphatase, catalytic subunit
GH1 growth hormone 1
GHR growth hormone receptor
GPX3 glutathione peroxidase 3
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HK2 hexokinase 2
HMGN5 high mobility group nucleosome binding domain 5
HOXA10 homeobox A10
HOXA11 homeobox A11
HP haptoglobin
HRAS Harvey rat sarcoma viral oncogene homolog
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGFBP1 insulin-like growth factor binding protein 1
IL11 interleukin 11
IL6 interleukin 6
INHA inhibin, alpha
INHBC inhibin, beta C
INSR insulin receptor
INTS2 integrator complex subunit 2
IRF1 interferon regulatory factor 1
ITGB4 integrin, beta 4
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KLF9 Kruppel-like factor 9
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT17 keratin 17, type I
LARP6 La ribonucleoprotein domain family, member 6
LAT linker for activation of T cells
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS9 lectin, galactoside-binding, soluble, 9
LIF leukemia inhibitory factor
LNPEP leucyl/cystinyl aminopeptidase
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LSR lipolysis stimulated lipoprotein receptor
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MME membrane metallo-endopeptidase
MMP12 matrix metallopeptidase 12
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP9 matrix metallopeptidase 9
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MSN moesin
MSTN myostatin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC16 mucin 16, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC6 mucin 6, oligomeric mucus/gel-forming
NDC80 NDC80 kinetochore complex component
NEU1 sialidase 1 (lysosomal sialidase)
NEURL1 neuralized E3 ubiquitin protein ligase 1
NOTCH1 notch 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NTSR1 neurotensin receptor 1 (high affinity)
OLFM4 olfactomedin 4
PAEP progestagen-associated endometrial protein
PARP1 poly (ADP-ribose) polymerase 1
PAX2 paired box 2
PCNA proliferating cell nuclear antigen
PGF placental growth factor
PGR progesterone receptor
PIGR polymeric immunoglobulin receptor
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
POTEF POTE ankyrin domain family, member F
POU5F1 POU class 5 homeobox 1
PPARD peroxisome proliferator-activated receptor delta
PPIB peptidylprolyl isomerase B (cyclophilin B)
PPME1 protein phosphatase methylesterase 1
PRB1 proline-rich protein BstNI subfamily 1
PTEN phosphatase and tensin homolog
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RACGAP1 Rac GTPase activating protein 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBP1 retinol binding protein 1, cellular
RCAN1 regulator of calcineurin 1
RHOC ras homolog family member C
RPE65 retinal pigment epithelium-specific protein 65kDa
RPL36A ribosomal protein L36a
RRM2 ribonucleotide reductase M2
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SHBG sex hormone-binding globulin
SLC12A9 solute carrier family 12, member 9
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC16A4 solute carrier family 16, member 4
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLIT2 slit homolog 2 (Drosophila)
SLIT3 slit homolog 3 (Drosophila)
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SPRY4 sprouty homolog 4 (Drosophila)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STOML2 stomatin (EPB72)-like 2
SYTL2 synaptotagmin-like 2
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
THBS2 thrombospondin 2
THEMIS2 thymocyte selection associated family member 2
TNC tenascin C
TNF tumor necrosis factor
TP53 tumor protein p53
TP63 tumor protein p63
TSG101 tumor susceptibility 101
UCN urocortin
UVRAG UV radiation resistance associated
VEGFA vascular endothelial growth factor A
WIF1 WNT inhibitory factor 1
WNT7A wingless-type MMTV integration site family, member 7A