Endosulfan Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A cyclic sulfite ester that is 1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine 3-oxide substituted by chloro groups at positions 6, 7, 8, 9, 10 and 10. (Chemical Entities of Biological Interest Ontology, CHEBI_4791)
External Link http://ctdbase.org/detail.go?type=chem&acc=D004726
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Genes

82 genes/proteins interacting with the chemical Endosulfan from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACHE acetylcholinesterase (Yt blood group)
ACTA2 actin, alpha 2, smooth muscle, aorta
AKT1 v-akt murine thymoma viral oncogene homolog 1
AR androgen receptor
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CAT catalase
CCND1 cyclin D1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
COL1A1 collagen, type I, alpha 1
CR2 complement component (3d/Epstein Barr virus) receptor 2
CREB1 cAMP responsive element binding protein 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
G6PD glucose-6-phosphate dehydrogenase
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1
GGT1 gamma-glutamyltransferase 1
GH1 growth hormone 1
GJA1 gap junction protein, alpha 1, 43kDa
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GPX1 glutathione peroxidase 1
GSK3B glycogen synthase kinase 3 beta
GSR glutathione reductase
HOXA1 homeobox A1
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPB1 heat shock 27kDa protein 1
IL1B interleukin 1, beta
IL6 interleukin 6
JUN jun proto-oncogene
LEF1 lymphoid enhancer-binding factor 1
LHB luteinizing hormone beta polypeptide
LIF leukemia inhibitory factor
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR1I3 nuclear receptor subfamily 1, group I, member 3
PGR progesterone receptor
PLAT plasminogen activator, tissue
PRL prolactin
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SI sucrase-isomaltase (alpha-glucosidase)
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SORD sorbitol dehydrogenase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TNF tumor necrosis factor
TSHB thyroid stimulating hormone, beta
VIM vimentin