Endotoxemia Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D019446
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Genes

102 genes/proteins associated with the disease Endotoxemia from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
SOD2 superoxide dismutase 2, mitochondrial 2.88009
ALOX5 arachidonate 5-lipoxygenase 2.88009
OTC ornithine carbamoyltransferase 2.88009
HSPA9 heat shock 70kDa protein 9 (mortalin) 2.88009
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 2.88009
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 2.88009
HSPD1 heat shock 60kDa protein 1 (chaperonin) 2.88009
NOS2 nitric oxide synthase 2, inducible 2.88009
IL6 interleukin 6 1.88293
TNF tumor necrosis factor 1.88209
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.88109
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.78168
IL1B interleukin 1, beta 1.75973
ICAM1 intercellular adhesion molecule 1 1.75102
SELE selectin E 1.66878
CXCL10 chemokine (C-X-C motif) ligand 10 1.66511
MPO myeloperoxidase 1.63698
NOS3 nitric oxide synthase 3 (endothelial cell) 1.61667
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.59802
IFNG interferon, gamma 1.55451
CCL3 chemokine (C-C motif) ligand 3 1.54159
CXCL8 chemokine (C-X-C motif) ligand 8 1.52338
TIMP1 TIMP metallopeptidase inhibitor 1 1.48864
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.47889
STAT1 signal transducer and activator of transcription 1, 91kDa 1.46383
VCAM1 vascular cell adhesion molecule 1 1.45883
CCL2 chemokine (C-C motif) ligand 2 1.42562
TGFB1 transforming growth factor, beta 1 1.40815
VEGFA vascular endothelial growth factor A 1.38043
MAPK3 mitogen-activated protein kinase 3 1.3759
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.37303
NOS1 nitric oxide synthase 1 (neuronal) 1.37189
CXCL2 chemokine (C-X-C motif) ligand 2 1.36961
CAT catalase 1.36848
MAPK1 mitogen-activated protein kinase 1 1.36763
HMGB1 high mobility group box 1 1.34694
IL10 interleukin 10 1.34372
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.33966
TLR4 toll-like receptor 4 1.33494
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.32637
NFE2L2 nuclear factor, erythroid 2-like 2 1.32369
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.31178
MMP9 matrix metallopeptidase 9 1.3103
HSPA1A heat shock 70kDa protein 1A 1.30604
PPARG peroxisome proliferator-activated receptor gamma 1.29875
IRS1 insulin receptor substrate 1 1.29256
IL12B interleukin 12B 1.27533
NCF1 neutrophil cytosolic factor 1 1.27378
IL4 interleukin 4 1.27224
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.27101
HMOX1 heme oxygenase 1 1.26298
FABP4 fatty acid binding protein 4, adipocyte 1.2509
LEP leptin 1.24118
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.22853
SOD1 superoxide dismutase 1, soluble 1.22758
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.2208
GSTT1 glutathione S-transferase theta 1 1.21206
FOS FBJ murine osteosarcoma viral oncogene homolog 1.20848
PLAT plasminogen activator, tissue 1.19639
BAD BCL2-associated agonist of cell death 1.19542
ALB albumin 1.18554
NQO1 NAD(P)H dehydrogenase, quinone 1 1.17728
EDN1 endothelin 1 1.16933
FASN fatty acid synthase 1.16567
HSPB1 heat shock 27kDa protein 1 1.16368
IGF1 insulin-like growth factor 1 (somatomedin C) 1.16302
CD40 CD40 molecule, TNF receptor superfamily member 5 1.16001
PRKCB protein kinase C, beta 1.15661
PPARA peroxisome proliferator-activated receptor alpha 1.15458
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.15391
CYBB cytochrome b-245, beta polypeptide 1.14885
CHUK conserved helix-loop-helix ubiquitous kinase 1.14713
JUN jun proto-oncogene 1.14336
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.13415
MAPK14 mitogen-activated protein kinase 14 1.13245
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.12838
IL1RN interleukin 1 receptor antagonist 1.12838
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.11673
LBP lipopolysaccharide binding protein 1.10562
MMP3 matrix metallopeptidase 3 1.09576
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.09436
PECAM1 platelet/endothelial cell adhesion molecule 1 1.08655
IGFBP3 insulin-like growth factor binding protein 3 1.07128
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.06552
LDLR low density lipoprotein receptor 1.06515
FSHB follicle stimulating hormone, beta polypeptide 1.05535
MMP1 matrix metallopeptidase 1 1.04978
CD36 CD36 molecule (thrombospondin receptor) 1.04611
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.04574
IL18 interleukin 18 1.04389
HNF4A hepatocyte nuclear factor 4, alpha 1.04276
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.04163
XDH xanthine dehydrogenase 1.03604
CLU clusterin 1.03567
TFRC transferrin receptor 1.03122
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.02933
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.02373
ADIPOQ adiponectin, C1Q and collagen domain containing 1.02262
STAR steroidogenic acute regulatory protein 1.02077
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.01814
DDIT3 DNA-damage-inducible transcript 3 1.01776
TH tyrosine hydroxylase 1.01324