| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entecavir (monohydrate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Entecavir (monohydrate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.312601 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.166817 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.164367 |
| PODXL | podocalyxin-like | 0.1332 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.116098 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.106676 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0999644 |
| SLC39A11 | solute carrier family 39, member 11 | 0.080499 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0769311 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.075348 |
| CDH13 | cadherin 13 | 0.0634874 |
| EGFR | epidermal growth factor receptor | 0.0626309 |
| COL5A1 | collagen, type V, alpha 1 | 0.0613423 |
| ATP13A3 | ATPase type 13A3 | 0.0606887 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0561987 |
| LOX | lysyl oxidase | 0.0553324 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0543658 |
| LDHA | lactate dehydrogenase A | 0.0540947 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.053966 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0536926 |
| FLNB | filamin B, beta | 0.0517072 |
| MSN | moesin | 0.0499217 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0491316 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0484771 |
| NAV2 | neuron navigator 2 | 0.0476663 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0462063 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0458759 |
| RUNX1 | runt-related transcription factor 1 | 0.0444547 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0435641 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0430704 |
| SEPTIN9 | septin 9 | 0.0428352 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0423213 |
| POTEF | POTE ankyrin domain family, member F | 0.0421643 |
| PRELID2 | PRELI domain containing 2 | 0.0414661 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0409097 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0399392 |
| HDAC9 | histone deacetylase 9 | 0.0388526 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0378178 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0350303 |
| AUTS2 | autism susceptibility candidate 2 | 0.0346969 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0346589 |
| CD109 | CD109 molecule | 0.0345993 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0345599 |
| C1D | C1D nuclear receptor corepressor | 0.0342832 |
| TLE4 | transducin-like enhancer of split 4 | 0.0341352 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0337638 |
| NBAS | neuroblastoma amplified sequence | 0.0332066 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0330072 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0328542 |
| DST | dystonin | 0.0328083 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0325409 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0322564 |
| YEATS2 | YEATS domain containing 2 | 0.0319603 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0315802 |
| TAOK1 | TAO kinase 1 | 0.0314512 |
| NDRG1 | N-myc downstream regulated 1 | 0.0311489 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0309561 |
| GOLGA4 | golgin A4 | 0.0308831 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.030872 |
| EFNA5 | ephrin-A5 | 0.0305294 |
| SMYD3 | SET and MYND domain containing 3 | 0.0304584 |
| RHOA | ras homolog family member A | 0.0295582 |
| USP34 | ubiquitin specific peptidase 34 | 0.0291744 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0289727 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0284513 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0284371 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0284054 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0281066 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0281051 |
| PCBP2 | poly(rC) binding protein 2 | 0.0280189 |
| CEP170 | centrosomal protein 170kDa | 0.0280144 |
| BCL2L1 | BCL2-like 1 | 0.0279272 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0279101 |
| TPM3 | tropomyosin 3 | 0.0279021 |
| PLAT | plasminogen activator, tissue | 0.0273809 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0273705 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0272884 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0271789 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0271262 |
| PKM | pyruvate kinase, muscle | 0.0269621 |
| SP3 | Sp3 transcription factor | 0.0267272 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0265699 |
| ZNF148 | zinc finger protein 148 | 0.0265316 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0262271 |
| JMJD1C | jumonji domain containing 1C | 0.0262227 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0262207 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0262183 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0260401 |
| COPA | coatomer protein complex, subunit alpha | 0.0256088 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0251818 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0249589 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0249506 |
| FNIP1 | folliculin interacting protein 1 | 0.0248248 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0247335 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.024243 |
| MED13 | mediator complex subunit 13 | 0.0241921 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0240314 |
| RNF144A | ring finger protein 144A | 0.0239906 |
| PFKP | phosphofructokinase, platelet | 0.023966 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.0239086 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.229271 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.22026 |
| MT2A | metallothionein 2A | -0.179563 |
| VIM | vimentin | -0.154577 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.11216 |
| HLA-B | major histocompatibility complex, class I, B | -0.0850812 |
| CSTB | cystatin B (stefin B) | -0.0740359 |
| PTMA | prothymosin, alpha | -0.0710438 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.068257 |
| FTL | ferritin, light polypeptide | -0.0609135 |
| S100A10 | S100 calcium binding protein A10 | -0.0585497 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0510162 |
| B2M | beta-2-microglobulin | -0.0490911 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0468226 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.046223 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0433609 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0399999 |
| MT1X | metallothionein 1X | -0.0384444 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0376757 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0368877 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.036796 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0367822 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0356376 |
| IER3 | immediate early response 3 | -0.0350469 |
| UBC | ubiquitin C | -0.0348253 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0338374 |
| MEIS2 | Meis homeobox 2 | -0.0327525 |
| GNAS | GNAS complex locus | -0.0325615 |
| HLA-C | major histocompatibility complex, class I, C | -0.0311981 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0309044 |
| S100A6 | S100 calcium binding protein A6 | -0.0308567 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0307238 |
| MX2 | MX dynamin-like GTPase 2 | -0.030492 |
| CD44 | CD44 molecule (Indian blood group) | -0.0298171 |
| COL3A1 | collagen, type III, alpha 1 | -0.0289475 |
| RPL36 | ribosomal protein L36 | -0.0289308 |
| SLC38A1 | solute carrier family 38, member 1 | -0.027927 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0273931 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0270235 |
| LMNA | lamin A/C | -0.0268434 |
| TMSB4X | thymosin beta 4, X-linked | -0.0268291 |
| CAVIN1 | caveolae associated protein 1 | -0.0266473 |
| FBN1 | fibrillin 1 | -0.0262402 |
| RPLP1 | ribosomal protein, large, P1 | -0.0260969 |
| S100A11 | S100 calcium binding protein A11 | -0.0260373 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0258573 |
| RPL32 | ribosomal protein L32 | -0.0257262 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0256644 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0255505 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0247846 |
| HLA-E | major histocompatibility complex, class I, E | -0.0242363 |
| KLF6 | Kruppel-like factor 6 | -0.0241427 |
| TXNIP | thioredoxin interacting protein | -0.0240447 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0240119 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0238851 |
| S100A9 | S100 calcium binding protein A9 | -0.0235939 |
| AHNAK | AHNAK nucleoprotein | -0.0233732 |
| RPS19 | ribosomal protein S19 | -0.0225887 |
| NPR2 | natriuretic peptide receptor 2 | -0.0222326 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0220956 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0215793 |
| RPL12 | ribosomal protein L12 | -0.0208899 |
| HMGB2 | high mobility group box 2 | -0.0206757 |
| PRSS23 | protease, serine, 23 | -0.0205071 |
| MKI67 | marker of proliferation Ki-67 | -0.0204412 |
| RPL28 | ribosomal protein L28 | -0.0204068 |
| RPL23 | ribosomal protein L23 | -0.0203973 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0203917 |
| FAM162A | family with sequence similarity 162, member A | -0.0202863 |
| TUBB | tubulin, beta class I | -0.0201259 |
| CANX | calnexin | -0.019918 |
| SERF2 | small EDRK-rich factor 2 | -0.0199059 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0197366 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0196932 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0196699 |
| PSMA2 | proteasome (prosome, macropain) subunit, alpha type, 2 | -0.0195018 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.019422 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0193852 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0191805 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0190608 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0189106 |
| HMGB1 | high mobility group box 1 | -0.0188752 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0187326 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0186677 |
| SEC61G | Sec61 gamma subunit | -0.0186611 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0183686 |
| TRIM56 | tripartite motif containing 56 | -0.0182384 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0181072 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0180632 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0180579 |
| RPL19 | ribosomal protein L19 | -0.018037 |
| THBS2 | thrombospondin 2 | -0.0178547 |
| COL1A2 | collagen, type I, alpha 2 | -0.017834 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.0176416 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0176394 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0176081 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0175515 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0174727 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0172089 |
| SON | SON DNA binding protein | -0.0170199 |
