| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entecavir (monohydrate) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Entecavir (monohydrate)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.154354 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.123616 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.095952 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0877634 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.069351 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0681766 |
| CCNL1 | cyclin L1 | 0.06232 |
| RBM39 | RNA binding motif protein 39 | 0.0610376 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0610009 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0584484 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.056893 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0540077 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0538365 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | 0.0521367 |
| TXNRD1 | thioredoxin reductase 1 | 0.050507 |
| RRM2 | ribonucleotide reductase M2 | 0.0501649 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0470472 |
| EDN1 | endothelin 1 | 0.0468975 |
| MGAT4C | MGAT4 family, member C | 0.0450288 |
| PCBP2 | poly(rC) binding protein 2 | 0.0446302 |
| DIAPH3 | diaphanous-related formin 3 | 0.0443974 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0436346 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0427114 |
| SEPTIN7 | septin 7 | 0.0422173 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0421323 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0414593 |
| XPO1 | exportin 1 | 0.0412518 |
| PARD3 | par-3 family cell polarity regulator | 0.0400702 |
| EPHA6 | EPH receptor A6 | 0.0397907 |
| MATR3 | matrin 3 | 0.0397577 |
| ZNF292 | zinc finger protein 292 | 0.039505 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0393589 |
| WDR43 | WD repeat domain 43 | 0.0370833 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0369697 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0361933 |
| ECT2 | epithelial cell transforming 2 | 0.0359031 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0358608 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0352143 |
| VMP1 | vacuole membrane protein 1 | 0.0349892 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0348302 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.034319 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0336925 |
| RPS20 | ribosomal protein S20 | 0.0330856 |
| SYT1 | synaptotagmin I | 0.0328353 |
| MKI67 | marker of proliferation Ki-67 | 0.0328135 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0325171 |
| RPLP0 | ribosomal protein, large, P0 | 0.0323769 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0323546 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0322734 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0322457 |
| PTK2 | protein tyrosine kinase 2 | 0.0317345 |
| HELLS | helicase, lymphoid-specific | 0.0315559 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0315025 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0313579 |
| CBX3 | chromobox homolog 3 | 0.0313017 |
| NDC80 | NDC80 kinetochore complex component | 0.0312597 |
| SETD5 | SET domain containing 5 | 0.0307574 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0307243 |
| ANXA1 | annexin A1 | 0.030218 |
| YEATS2 | YEATS domain containing 2 | 0.0300994 |
| KIF5B | kinesin family member 5B | 0.0299318 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0298572 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0295795 |
| RPS12 | ribosomal protein S12 | 0.0295585 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.029405 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0292877 |
| MED13L | mediator complex subunit 13-like | 0.0292276 |
| YBX3 | Y box binding protein 3 | 0.0292235 |
| THOC1 | THO complex 1 | 0.0292107 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0289409 |
| PNN | pinin, desmosome associated protein | 0.0287189 |
| RPLP1 | ribosomal protein, large, P1 | 0.0285137 |
| CCDC88A | coiled-coil domain containing 88A | 0.0284847 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0284057 |
| RBM25 | RNA binding motif protein 25 | 0.0283839 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0282432 |
| DEK | DEK proto-oncogene | 0.0280791 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0280719 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0280604 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.0280286 |
| CDK19 | cyclin-dependent kinase 19 | 0.0279403 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0278627 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0278173 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0277529 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0273238 |
| RPL27A | ribosomal protein L27a | 0.0270948 |
| THOC2 | THO complex 2 | 0.0268894 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0267288 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0264479 |
| RPS19 | ribosomal protein S19 | 0.026253 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0259962 |
| NEK7 | NIMA-related kinase 7 | 0.0259607 |
| LDHB | lactate dehydrogenase B | 0.0257542 |
| R3HDM1 | R3H domain containing 1 | 0.0255656 |
| IMMT | inner membrane protein, mitochondrial | 0.0253453 |
| CDCA2 | cell division cycle associated 2 | 0.0253255 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0252084 |
| TBK1 | TANK-binding kinase 1 | 0.025157 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0250993 |
| CPOX | coproporphyrinogen oxidase | 0.0250927 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.112205 |
| NLGN1 | neuroligin 1 | -0.0942273 |
| MMP12 | matrix metallopeptidase 12 | -0.0792119 |
| UBC | ubiquitin C | -0.0754195 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0714901 |
| RPS27A | ribosomal protein S27a | -0.0558806 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0481174 |
| ZNF804A | zinc finger protein 804A | -0.0457095 |
| RPL23 | ribosomal protein L23 | -0.0456236 |
| TMSB10 | thymosin beta 10 | -0.0432858 |
| AHNAK | AHNAK nucleoprotein | -0.0413035 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0412023 |
| ENO1 | enolase 1, (alpha) | -0.0403971 |
| DST | dystonin | -0.0369166 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0366523 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0344352 |
| CMIP | c-Maf inducing protein | -0.0325564 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0321301 |
| HMGA2 | high mobility group AT-hook 2 | -0.0317478 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0316117 |
| MYPN | myopalladin | -0.0315718 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0291598 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0284496 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0282311 |
| SETX | senataxin | -0.0273083 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0270699 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0258213 |
| DTNA | dystrobrevin, alpha | -0.0249654 |
| NABP1 | nucleic acid binding protein 1 | -0.024103 |
| ACTG1 | actin gamma 1 | -0.0231754 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0226645 |
| EHBP1 | EH domain binding protein 1 | -0.0226299 |
| VCL | vinculin | -0.0225914 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | -0.0225058 |
| ADIPOR2 | adiponectin receptor 2 | -0.0223543 |
| CALR | calreticulin | -0.0222572 |
| RNF213 | ring finger protein 213 | -0.0207231 |
| EGR1 | early growth response 1 | -0.0204366 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0201869 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0194405 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0189291 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0188677 |
| TGM2 | transglutaminase 2 | -0.0187122 |
| PHF14 | PHD finger protein 14 | -0.018703 |
| INTS6 | integrator complex subunit 6 | -0.0185478 |
| RCOR1 | REST corepressor 1 | -0.0184501 |
| NRXN3 | neurexin 3 | -0.0184489 |
| THRAP3 | thyroid hormone receptor associated protein 3 | -0.0182782 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0181044 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0178557 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0177298 |
| DGUOK | deoxyguanosine kinase | -0.0169261 |
| RPL26 | ribosomal protein L26 | -0.0168819 |
| KSR2 | kinase suppressor of ras 2 | -0.0168228 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0167943 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0166983 |
| AEBP2 | AE binding protein 2 | -0.0164518 |
| RPL11 | ribosomal protein L11 | -0.0164376 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0161584 |
| KIAA0232 | KIAA0232 | -0.0157871 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0154248 |
| RPS3 | ribosomal protein S3 | -0.0154014 |
| NRDC | nardilysin convertase | -0.0153691 |
| DENND5B | DENN/MADD domain containing 5B | -0.0153623 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0153245 |
| CUL4A | cullin 4A | -0.0149432 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0148957 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0148778 |
| CLDN1 | claudin 1 | -0.0147287 |
| RSU1 | Ras suppressor protein 1 | -0.0144486 |
| ACTN4 | actinin, alpha 4 | -0.0144137 |
| MTAP | methylthioadenosine phosphorylase | -0.0141914 |
| EDARADD | EDAR-associated death domain | -0.014173 |
| BCHE | butyrylcholinesterase | -0.0140541 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.0140054 |
| RIMKLB | ribosomal modification protein rimK-like family member B | -0.0139929 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0138654 |
| CDK12 | cyclin-dependent kinase 12 | -0.0137637 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0136582 |
| IP6K1 | inositol hexakisphosphate kinase 1 | -0.0135719 |
| MCL1 | myeloid cell leukemia 1 | -0.0135046 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0134941 |
| AATF | apoptosis antagonizing transcription factor | -0.0134868 |
| INTS4 | integrator complex subunit 4 | -0.013446 |
| FAT1 | FAT atypical cadherin 1 | -0.0134306 |
| ANKRD17 | ankyrin repeat domain 17 | -0.013417 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0133818 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.013356 |
| LATS2 | large tumor suppressor kinase 2 | -0.0133038 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0132226 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0131432 |
| CFAP70 | cilia and flagella associated protein 70 | -0.0130021 |
| KMT2D | lysine (K)-specific methyltransferase 2D | -0.0129705 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0127734 |
| PMM2 | phosphomannomutase 2 | -0.0127715 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0127017 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0126754 |
| ETV6 | ets variant 6 | -0.0125905 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0125584 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0124966 |
