| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entecavir (monohydrate) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Entecavir (monohydrate)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.13631 |
| USP3 | ubiquitin specific peptidase 3 | 0.102102 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0961875 |
| LDHA | lactate dehydrogenase A | 0.0943246 |
| SPAG9 | sperm associated antigen 9 | 0.0888935 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0871813 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0823422 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0774459 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0718965 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0715742 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0682759 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0662531 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0649244 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0644366 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0642383 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0641169 |
| SMAD3 | SMAD family member 3 | 0.0617279 |
| HELZ | helicase with zinc finger | 0.0614834 |
| GOLGA4 | golgin A4 | 0.0586285 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0571107 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0558234 |
| UBC | ubiquitin C | 0.0549593 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0538124 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0535179 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0525681 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0524427 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0501722 |
| NUP58 | nucleoporin 58 | 0.049758 |
| KCTD9 | potassium channel tetramerization domain containing 9 | 0.049404 |
| PCBP2 | poly(rC) binding protein 2 | 0.0481372 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0476437 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0442991 |
| PKM | pyruvate kinase, muscle | 0.0437527 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.042803 |
| TFG | TRK-fused gene | 0.0423084 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0421584 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0417017 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.041627 |
| SETD5 | SET domain containing 5 | 0.0415054 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0413272 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0411895 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0411775 |
| POTEF | POTE ankyrin domain family, member F | 0.0397908 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0393821 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0389794 |
| NDRG1 | N-myc downstream regulated 1 | 0.0388241 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0378705 |
| PTMA | prothymosin, alpha | 0.0378147 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.036439 |
| WDR43 | WD repeat domain 43 | 0.0355857 |
| NBAS | neuroblastoma amplified sequence | 0.0353814 |
| DSTN | destrin (actin depolymerizing factor) | 0.0352181 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0351571 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0344453 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0341962 |
| ZNF292 | zinc finger protein 292 | 0.0341521 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0340042 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0338623 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.033797 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0332623 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0331771 |
| TBK1 | TANK-binding kinase 1 | 0.0330932 |
| PGK1 | phosphoglycerate kinase 1 | 0.0329294 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0319455 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0318788 |
| ATP13A3 | ATPase type 13A3 | 0.0315544 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0314454 |
| CANX | calnexin | 0.0312383 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0309401 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0308016 |
| RBM39 | RNA binding motif protein 39 | 0.0304477 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0304128 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0303825 |
| TKT | transketolase | 0.0303218 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0301124 |
| MCL1 | myeloid cell leukemia 1 | 0.0299154 |
| MORF4L2 | mortality factor 4 like 2 | 0.0295889 |
| EREG | epiregulin | 0.0293192 |
| VIM | vimentin | 0.0292532 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0289256 |
| ECT2 | epithelial cell transforming 2 | 0.0281093 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0280263 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0277377 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0268707 |
| DENND4C | DENN/MADD domain containing 4C | 0.0268564 |
| SEC24A | SEC24 family member A | 0.0267222 |
| NGLY1 | N-glycanase 1 | 0.0266708 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0266516 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0265825 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.026486 |
| AXL | AXL receptor tyrosine kinase | 0.0264485 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0264289 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0260613 |
| SEPTIN7 | septin 7 | 0.0259322 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0258967 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0258783 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0257796 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0257592 |
| TPR | translocated promoter region, nuclear basket protein | 0.0257214 |
| CA12 | carbonic anhydrase XII | 0.0256537 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.199662 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.153996 |
| TMSB10 | thymosin beta 10 | -0.114499 |
| MT1X | metallothionein 1X | -0.0998284 |
| PDE10A | phosphodiesterase 10A | -0.0866252 |
| EGFR | epidermal growth factor receptor | -0.0775264 |
| RPS19 | ribosomal protein S19 | -0.0753732 |
| EFNA5 | ephrin-A5 | -0.0725691 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0654084 |
| VCL | vinculin | -0.062091 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0586299 |
| KYNU | kynureninase | -0.0559295 |
| OSMR | oncostatin M receptor | -0.0533458 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0492893 |
| EHBP1 | EH domain binding protein 1 | -0.0457506 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0454645 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0449299 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0424996 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0385281 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0361652 |
| RPL32 | ribosomal protein L32 | -0.0361463 |
| TNS3 | tensin 3 | -0.0331123 |
| RNF213 | ring finger protein 213 | -0.0326081 |
| RPL23 | ribosomal protein L23 | -0.0319772 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0313344 |
| NRG1 | neuregulin 1 | -0.030557 |
| GLIS3 | GLIS family zinc finger 3 | -0.0303064 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.029689 |
| HMGA2 | high mobility group AT-hook 2 | -0.0296835 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.028997 |
| RAD51B | RAD51 paralog B | -0.0275497 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0268186 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.026588 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | -0.0265223 |
| RRBP1 | ribosome binding protein 1 | -0.0264124 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0263075 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0262806 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0259004 |
| BICC1 | BicC family RNA binding protein 1 | -0.0248978 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0243612 |
| AUTS2 | autism susceptibility candidate 2 | -0.0236822 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0236667 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0233776 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0229263 |
| PRKCA | protein kinase C, alpha | -0.0227129 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0219664 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0218873 |
| EXT1 | exostosin glycosyltransferase 1 | -0.02183 |
| ST6GAL2 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 | -0.0217864 |
| LMO7 | LIM domain 7 | -0.0215667 |
| LAMC2 | laminin, gamma 2 | -0.0212037 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0206087 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0204483 |
| NTN4 | netrin 4 | -0.0203982 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0198068 |
| EGR1 | early growth response 1 | -0.0196411 |
| IGSF11 | immunoglobulin superfamily, member 11 | -0.0194357 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0192819 |
| RPL19 | ribosomal protein L19 | -0.0191949 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0191187 |
| RPL18 | ribosomal protein L18 | -0.0189455 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.018776 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0187713 |
| RIGI | RNA sensor RIG-I | -0.0187401 |
| RPL12 | ribosomal protein L12 | -0.0186929 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0186548 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0182357 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0180034 |
| NINL | ninein-like | -0.0179204 |
| CEP112 | centrosomal protein 112kDa | -0.017877 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0175844 |
| RAI14 | retinoic acid induced 14 | -0.0172942 |
| ZFHX3 | zinc finger homeobox 3 | -0.0172884 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.016962 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0169617 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0168752 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0167444 |
| SMAD2 | SMAD family member 2 | -0.0167186 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0166676 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0166499 |
| PALLD | palladin, cytoskeletal associated protein | -0.0165544 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0160684 |
| GABRB3 | gamma-aminobutyric acid (GABA) A receptor, beta 3 | -0.0160251 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0158609 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0157536 |
| RPLP2 | ribosomal protein, large, P2 | -0.0156788 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0156296 |
| PDE7B | phosphodiesterase 7B | -0.0154343 |
| TPM1 | tropomyosin 1 (alpha) | -0.0153866 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0152827 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0150412 |
| RPS21 | ribosomal protein S21 | -0.0150153 |
| NABP1 | nucleic acid binding protein 1 | -0.0150005 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0149472 |
| RHCG | Rh family, C glycoprotein | -0.0145501 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0145241 |
| RPS8 | ribosomal protein S8 | -0.0144134 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0144095 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0143424 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0143329 |
